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From observation to optimization: behavioral metrics that matter in KPI based home cage monitoring. [PDF]
Talbot SR +4 more
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Corrigendum: Anticancer activity of <i>Pseudomonas aeruginosa</i> derived peptide with iRGD in colon cancer therapy. [PDF]
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Application of the 3Rs principles in the development of pharmaceutical generics
Regulatory Toxicology and Pharmacology, 2021Although the 3Rs are broadly applied in nonclinical testing, a better appreciation of the 3Rs is needed in the field of differentiated or value-added pharmaceutical generics because the minor changes in formulation, dosage form, indication, and application route often do not require additional safety testing.
Abhijit S. Vichare +4 more
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3R Principle in Household Energy Consumption Patterns
2021Energy is an important issue for achieving sustainable development. Sustainable Development Goals emphasize renewable energy sources, green energy technologies, and energy efficiency for sustainable world. In addition, energy consumption patterns can influence energy efficiency as much as green energy policies.
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Application of 3R principles in testing recombinant vaccines
БИОТЕХНОЛОГИЯ: НАУЧНЫЕ ИССЛЕДОВАНИЯ И СВЯЗЬ С ПРОИЗВОДСТВОМThe article discusses the main provisions and principles of the 3R concept, which regulates the main provisions and approaches to working with laboratory animals. The concept itself consists of 3 areas: Replacement of animals in the experiment with other models, reduction of the use of animal objects by optimizing experimental conditions and ...
S.A. Vasiliev +2 more
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Noninvasive Small Rodent Imaging: Significance for the 3R Principles
2011Minimizing potential pain and distress as well as the number of animals in biomedical experimentation and in the drug discovery and development process is not only a moral imperative but also a challenging and evolving area of research. Non-invasive imaging can refine procedures by using alternative readouts which represent early disease state or ...
Nicolau Beckmann, Peter Maier
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The role of organizational culture in compliance with the principles of the 3Rs
Lab Animal, 2010In order for their research to be legitimate, scientists carrying out research using animals must comply with rules and regulations. The 3Rs (replacement, reduction and refinement) are one set of guidelines that help to promote the ethical use of animals for research.
Aurora, Brønstad +1 more
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