Results 171 to 180 of about 3,224 (210)

From observation to optimization: behavioral metrics that matter in KPI based home cage monitoring. [PDF]

open access: yesFront Behav Neurosci
Talbot SR   +4 more
europepmc   +1 more source

Application of the 3Rs principles in the development of pharmaceutical generics

Regulatory Toxicology and Pharmacology, 2021
Although the 3Rs are broadly applied in nonclinical testing, a better appreciation of the 3Rs is needed in the field of differentiated or value-added pharmaceutical generics because the minor changes in formulation, dosage form, indication, and application route often do not require additional safety testing.
Abhijit S. Vichare   +4 more
openaire   +2 more sources

3R Principle in Household Energy Consumption Patterns

2021
Energy is an important issue for achieving sustainable development. Sustainable Development Goals emphasize renewable energy sources, green energy technologies, and energy efficiency for sustainable world. In addition, energy consumption patterns can influence energy efficiency as much as green energy policies.
openaire   +1 more source

Application of 3R principles in testing recombinant vaccines

БИОТЕХНОЛОГИЯ: НАУЧНЫЕ ИССЛЕДОВАНИЯ И СВЯЗЬ С ПРОИЗВОДСТВОМ
The article discusses the main provisions and principles of the 3R concept, which regulates the main provisions and approaches to working with laboratory animals. The concept itself consists of 3 areas: Replacement of animals in the experiment with other models, reduction of the use of animal objects by optimizing experimental conditions and ...
S.A. Vasiliev   +2 more
openaire   +1 more source

Noninvasive Small Rodent Imaging: Significance for the 3R Principles

2011
Minimizing potential pain and distress as well as the number of animals in biomedical experimentation and in the drug discovery and development process is not only a moral imperative but also a challenging and evolving area of research. Non-invasive imaging can refine procedures by using alternative readouts which represent early disease state or ...
Nicolau Beckmann, Peter Maier
openaire   +1 more source

The role of organizational culture in compliance with the principles of the 3Rs

Lab Animal, 2010
In order for their research to be legitimate, scientists carrying out research using animals must comply with rules and regulations. The 3Rs (replacement, reduction and refinement) are one set of guidelines that help to promote the ethical use of animals for research.
Aurora, Brønstad   +1 more
openaire   +2 more sources

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