Results 81 to 90 of about 3,224 (210)
3R principle as minimum ethics in animal experimentation
Revista BioéticaAbstract Non-human animals are routinely used in research, although studies refute the premise that results generated in this way benefit society. Law 11,794/2008 established ethics committees on the use of animals, with the authority to normatively and ethically evaluate teaching and research protocols.
Renata Batista da Silva +1 more
openaire +1 more source
Business Strategy and the Environment, EarlyView.ABSTRACT The global manufacturing sector has increasingly adopted circular economy (CE) practices to address sustainability challenges and improve operational efficiency. This study explores the impact of five CE practices—reduce, reuse, remanufacture, recycle, and recover—on key operational performance dimensions: quality, speed, dependability ...
Jose Arturo Garza‐Reyes +5 more
wiley +1 more source
Toxins, 2020 Botulinum neurotoxins (BoNTs) are potent neurotoxins produced by bacteria, which inhibit neurotransmitter release, specifically in their physiological target known as motor neurons (MNs).
Maren Schenke +3 more
doaj +1 more source
Environmental Toxicology and Chemistry, EarlyView.Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz +9 more
wiley +1 more source
Interdisciplinary Medicine, EarlyView.Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui +12 more
wiley +1 more source
Frontiers in Veterinary Science, 2019 The Principles of the 3Rs apply to animal use in research regardless where the research is conducted. In wildlife research, particularly research on wild birds, 3R implementation lags behind research using laboratory, farm, or pet animals.
Adriaan de Jong
doaj +1 more source
Journal of Periodontology, EarlyView.Abstract Background The pathogenesis and etiology of peri‐implantitis demand a deeper understanding to lead to successful treatment modalities. Animal models of peri‐implantitis pathogenesis offer unique insights but their translational impact requires consideration of implant biomaterials science.
Georgios Kotsakis +15 more
wiley +1 more source
Strategy of Making Hand Washing a Routine Habit: Principles of 5Es and 3Rs
Journal of Nepal Medical Association, 2016 Regular hand washing habit has potential to reduce morbidity and mortality due to diseases and improves child development and reduces absenteeism of children, teachers and workforce. Improving hand washing behavior is more cost effective than improving clean water and sanitation infrastructure.
Nirmal Kandel, Jaya Lamichane
openaire +5 more sources
Polymer Engineering &Science, EarlyView.Crosslinked gelatin‐functionalized PCL scaffolds exhibited enhanced hydrophilicity, structural stability, and porous interactions. In vitro assays demonstrated improved osteoblast adhesion, viability, and proliferation without cytotoxicity, while in vivo evaluation showed no adverse inflammatory response, supporting their potential application in ...
Fernanda Ramírez‐Ruiz +7 more
wiley +1 more source
Sustainable Development, EarlyView.ABSTRACT Using the Theory of Planned Behavior, this study examines the determinants influencing Generation Z in adopting circular practices when traveling as tourists, focusing on 300 respondents from Majorca. Employing a PLS‐SEM framework, the research evaluates the influence of TPB factors on circular economy participation and investigates the impact
Marta Jacob +3 more
wiley +1 more source