Results 91 to 100 of about 13,717 (182)

4-Aminopyridine induced hyperpolarizing oscillations in pediatric human epileptic tissue are network-driven potassium currents that are abolished by activation of KCNQ2-5 (Kv7.2-Kv7.5) channels. [PDF]

Neurobiol Dis
Kushner JK, Hoffman PB, Brzezinski CR, O'Neill BR, Hankinson TC, Wilkinson CC, Handler MH, Hoeffer CA, Alexander AL.   +8 more
europepmc   +1 more source

4-Aminopyridine Induces Nerve Growth Factor to Improve Skin Wound Healing and Tissue Regeneration. [PDF]

Biomedicines, 2022
Jagadeeshaprasad MG, Govindappa PK, Nelson AM, Noble MD, Elfar JC.   +4 more
europepmc   +1 more source

Targeting Voltage-Gated Potassium Channels in Breast Cancer: Mechanistic Insights into 4-Aminopyridine-Induced Cell Death. [PDF]

Int J Mol Sci
Cüce-Aydoğmuş EM, İyiol P, İnhan-Garip GA.   +2 more
europepmc   +1 more source

4-Aminopyridine.

Journal of Synthetic Organic Chemistry, Japan, 1990
openaire   +2 more sources

Voltage gating and 4-aminopyridine inhibition in the Shaker Kv channel revealed by a closed-state model. [PDF]

Biophys J
Pinto-Anwandter BI.
europepmc   +1 more source

Human cerebral spheroids undergo 4-aminopyridine-induced, activity associated changes in cellular composition and microrna expression. [PDF]

Sci Rep, 2022
Parmentier T, James FMK, Hewitson E, Bailey C, Werry N, Sheridan SD, Perlis RH, Perreault ML, Gaitero L, Lalonde J, LaMarre J.   +10 more
europepmc   +1 more source

4-Aminopyridine Promotes BMP2 Expression and Accelerates Tibial Fracture Healing in Mice. [PDF]

J Bone Joint Surg Am
Ellur G, Govindappa PK, Govindappa PK, Subrahmanian S, Romero GF, Gonzales DA, Margolis DS, Elfar JC.   +7 more
europepmc   +1 more source

Optogenetic Low-Frequency Stimulation of Principal Neurons, but Not Parvalbumin-Positive Interneurons, Prevents Generation of Ictal Discharges in Rodent Entorhinal Cortex in an In Vitro 4-Aminopyridine Model. [PDF]

Int J Mol Sci, 2022
Proskurina EY, Chizhov AV, Zaitsev AV.
europepmc   +1 more source

Interneuron-Driven Ictogenesis in the 4-Aminopyridine Model: Depolarization Block and Potassium Accumulation Initiate Seizure-like Activity. [PDF]

Int J Mol Sci
Proskurina EY, Ergina JL, Zaitsev AV.
europepmc   +1 more source

Acute axon damage and demyelination are mitigated by 4-aminopyridine (4-AP) therapy after experimental traumatic brain injury. [PDF]

Acta Neuropathol Commun, 2022
Radomski KL, Zi X, Lischka FW, Noble MD, Galdzicki Z, Armstrong RC.   +5 more
europepmc   +1 more source