Results 81 to 90 of about 21,958 (218)
Synthesis of C-5" and C-6"-modified α-GalCer analogues as iNKT-cell agonists [PDF]
, 2015 Alpha-Galactosyl Ceramide (α-GalCer) is a prototypical synthetic ligand of invariant natural killer T (iNKT) cells. Upon presentation by the MHC class I-like molecule CD1d, this glycolipid stimulates iNKT cells to secrete a vast amount of both pro ...
ASPESLAGH, SANDRINE +5 more
core +1 more source
Movement Disorders in Developmental and Epileptic Encephalopathies
Movement Disorders Clinical Practice, EarlyView.Abstract Background Monogenic developmental and epileptic encephalopathies (DEE) frequently feature co‐occurring movement disorders. Gene discovery has expanded epilepsy‐dyskinesia syndromes (EDS) from classic associations such as stereotypies in Rett syndrome to PRRT2‐related infantile seizures with paroxysmal dyskinesia and crouched gait in SCN1A ...
Shekeeb Mohammad +2 more
wiley +1 more source
In vitro ictogenesis and parahippocampal networks in a rodent model of temporal lobe epilepsy
Neurobiology of Disease, 2010 Temporal lobe epilepsy (TLE) is a chronic epileptic disorder involving the hippocampal formation. Details on the interactions between the hippocampus proper and parahippocampal networks during ictogenesis remain, however, unclear.
G. Panuccio +5 more
doaj +1 more source
Late expression of FosB transcription factor in 4-aminopyridine-induced seizures in the rat cerebral cortex [PDF]
, 2008 In order to deliver services to citizens, public sector agencies of today offer various types of channels for interaction. In this article we aim to develop an understanding of the reciprocal relation between multi‑channel services and work prac tice. By
Bagosi, Andrea +3 more
core +1 more source
The photoswitchable ABAMIs for the future regulation of GWT1 in a spatiotemporal level
Smart Molecules, EarlyView.The GWT1‐targeted azobenzene‐aminopyridine derivatives (ABAMIs), sensitive to the light at wavelengths from 365 to 520 nm, are separately developed as photochromic ligands to regulate bioactivity as well as the GWT1 functions. These molecules are smart tools in photopharmacological studies, giving an innovative method for understanding functional GWT1 ...
Qian Ding +8 more
wiley +1 more source
Frontiers in Cellular Neuroscience, 2020 In the present study, we characterized the effects of bath application of the proconvulsant drug 4-aminopyridine (4-AP) alone or in combination with GABAA and/or GABAB receptor antagonists, in cortical dysplasia (CD type I and CD type IIa/b), tuberous ...
Simon Levinson +9 more
doaj +1 more source
Dispersing blackbirds and starlings from objectionable roost sites [PDF]
, 1980 Frightening devices and other methods of dispersing roosting blackbirds and starlings are described along with the techniques for their proper application.
Mott, Donald F.
core +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Blebbistatin reduces Ca2+ buffering in induced pluripotent stem cell‐derived atrial cardiomyocytes. Blebbistatin, a widely used excitation–contraction uncoupling agent, decreases calcium (Ca2+) buffer affinity (increased buffer dissociation constant), leading to elevated diastolic Ca2+ levels, increased sarcoplasmic reticulum Ca2+
Izzatullo Sobitov +8 more
wiley +1 more source
Fluids and Barriers of the CNSBackground The brain extracellular fluid (ECF), composed of secreted neurotransmitters, metabolites, peptides, and proteins, may reflect brain processes.
Vanda Tukacs +6 more
doaj +1 more source
catena-Poly[[silver(I)-μ-4-aminopyridine] perchlorate]: a 1-D staircase coordination polymer
Acta Crystallographica Section E, 2010 Reaction of 4-aminopyridine with silver(I) perchlorate leads to a one-dimensional coordination polymer, {[Ag(C5H6N2)]ClO4}n, in which the aminopyridine binds through both N atoms.
Peter J. Steel +3 more
doaj +1 more source