Results 71 to 80 of about 7,294,678 (325)
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Factors Contributing to the Retention of Senior 4-H Members: From the Youth Perspective
Journal of Human Sciences and Extension, 2018 Of the almost six million youth reported as 4-H members in 2014, only 610,161 were listed as students in grades 9–12, compared to 1,941,406 in grades 4–8. This great disparity has been a long-held concern of 4-H professionals.
Stacey Ellison, Amy Harder
doaj +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Psychosocial Maturity in 4-H and Non 4-H Youth
, 1981 This study was undertaken to add to the knowledge of the psychosocial effects of the 4-H program upon its members. The objectives were to determine if 4-H involvement is associated with the psychological and social maturation of adolescent members, and to investigate how several variables such as age, urban/rural residence, and S. E. S.
openaire +3 more sources
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Understanding the Effects of Lactose Hydrolysis Modeling on the Main Oligosaccharides in Goat Milk Whey Permeate. [PDF]
, 2019 Enzymatic hydrolysis of lactose is a crucial step to improve the efficiency and selectivity of membrane-based separations toward the recovery of milk oligosaccharides free from simple sugars.
Barile, Daniela +5 more
core +2 more sources
Youth Sparks via 4-H: Relations with Program Quality, Dosage, and Involvement
Journal of Human Sciences and ExtensionUsing a statewide sample of participants in 4-H programs, we tested associations among youth sparks, program quality, program dosage, and four types of involvement (breadth of participation in out-of-school-time beyond 4-H, scope of learning ...
Alexandra Skrocki +3 more
doaj +1 more source
Discover 4-H Clubs: The Essential Resource for 4-H
Journal of Extension, 2016 Obstacles facing new 4-H volunteers include time constraints and difficulty finding project-specific information, resources, and opportunities available for club members. As a solution to these obstacles and an aid for assisting volunteers in becoming confident in delivering information to youth, content experts produced Discover 4-H Clubs, a ...
MacArthur, Stacey +4 more
openaire +2 more sources
Purification tags markedly affect self‐aggregation of CPEB3
FEBS Letters, EarlyView.Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito +6 more
wiley +1 more source