Results 61 to 70 of about 597,947 (275)

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

Infection Control Practices for Vascular Access Management in Hemodialysis: Results From a Nationwide Survey of Japanese National University Hospitals

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Bloodstream infections due to repeated vascular access (VA) puncture and circuit connections remain major concerns in hemodialysis. Therefore, we examined current practices for glove, disinfectant, and personal protective equipment (PPE) use according to VA type in national university hospitals in Japan.
Aiko Yamada, Makoto Harada, Tadahiko Kikugawa, Takeshi Nakata, Koji Hashimoto, Tsuneo Konta, Yuji Kamijo   +6 more
wiley   +1 more source

The Workplace Relevance of the Liberal Arts Political Science BA and How It Might Be Enhanced: Reflections on an Exploratory Survey of the NGO Sector [PDF]

, 2013
Reflecting on a survey of employees of NGOs based in Ontario, Canada, the article considers two questions: How well are our BA programs preparing students for the workplace? Can we enhance workplace relevance without sacrificing our commitment to liberal
Robinson, Andrew M
core   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Proximity to Sports Facilities and Sports Participation for Adolescents in Germany [PDF]

, 2014
Objectives - To assess the relationship between proximity to specific sports facilities and participation in the corresponding sports activities for adolescents in Germany. Methods - A sample of 1,768 adolescents aged 11–17 years old and living in 161
A Sagatun, A Steinmayr, A Woll, Alexander Woll, Andreas Steinmayr, Anne K. Reimers, AVD Roux, B Giles-Corti, B Niclasen, B Swinburn, BM Kurth, BM Kurth, BYM Wong, CG Owen, D Jekauc, D Jekauc, H Hölling, HM Grow, I Janssen, J Brug, JB Moore, JC Spence, K Ball, KK Davison, L Schenk, LE Thornton, LM Powell, Matthias Wagner, MD Hanson, Miriam Reiner, N Owen, NH Brodersen, P Gordon-Larsen, P Kamtsiuris, PC Hallal, R Telama, Reury F. P. Bacurau, RG Prins, RG Prins, RG Prins, RG Prins, S Macintyre, Seraphim Alvanides, SJ Biddle, Steffen Schmidt, T Burgoine, T Lampert, T Pikora, X Yang   +48 more
core   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

The Cowl - v.16 - n.8 - Dec 09, 1953 [PDF]

, 1953
The Cowl - student newspaper of Providence College. Volume 16, Number 8 - Dec 09, 1953, 1951.

core   +1 more source

Exploring the costs and outcomes of sexually transmitted infection (STI) screening interventions targeting men in football club settings: preliminary cost-consequence analysis of the SPORTSMART pilot randomised controlled trial [PDF]

, 2014
Background: The objective of this study was to compare the costs and outcomes of two sexually transmitted infection (STI) screening interventions targeted at men in football club settings in England, including screening promoted by team captains ...
Andrew J Copas, Baraitser, Buhrer-Skinner, Cassell, Catherine H Mercer, Claudia S Estcourt, Curtis, Deogan, Drummond, Fuller, Hengel, Jackie A Cassell, John M Saunders, Lorna J Sutcliffe, Louise J Jackson, Morris, Roberts, Robinson, Saunders, Sebastian S Fuller, Tracy E Roberts, Williamson   +21 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source