Results 71 to 80 of about 597,947 (275)

Procedure for Handling 4-H Accounts: Rights and Responsibilities

EDIS, 2007
4H5.3, a 3-page factsheet by Marilyn N. Norman and Joy C. Jordan, explains accounting procedures for all 4-H clubs regarding record-keeping and handling cash. Published by the UF Department of Family, Youth and Community Sciences, February 2007.
Marilyn N. Norman, Joy C. Jordan
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Moving from information and collaboration to action: report from the 3rd International Dog Health Workshop, Paris in April 2017 [PDF]

, 2017
Background Breed-related health problems in dogs have received increased focus over the last decade. Responsibility for causing and/or solving these problems has been variously directed towards dog breeders and kennel clubs, the veterinary profession ...
A Bartels, AIDAP, AJ Clarke, APGAW, APGAW, APGAW, C Greko, C Mellersh, D O'Neill, DG O'Neill, DG O'Neill, DG O’Neill, FW Nicholas, G Leroy, German Kennel Club (VDH), International Partnership for Dogs (IPFD), J Donner, J Serpell, JE Simmering, JG Scott, JP Scott, JY Kwan, K Arman, L Asher, L Beever, L Farrell, L Lilja-Maula, LM Collins, LM Collins, N Couto, NJ Beausoleil, O Ljungquist, P Bateson, P Sandøe, PC Bartlett, PD McGreevy, PD McGreevy, R Packer, R Proctor, R Ryan, RMA Packer, RMA Packer, RMA Packer, RMA Packer, S Ghirlanda, S Ghirlanda, T Pires dos Santos, The Swedish Kennel Club, VJ Adams, ÅA Hedhammar, ÅA Hedhammar   +50 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Exploring Citizenship Unit III: My Clubs and Groups

EDIS, 2018
The 4-H Citizenship Project offers you the opportunity to help 4-H members relate all of their 4-H projects and experiences to the world around them.
Joy Jordan
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Florida 4-H Shooting Sports Instructor Training & Certification - Volunteer Leader Training Series

EDIS, 2019
A successful county Shooting Sports program is not possible without screened and trained volunteers to lead clubs. Before instructing youth in any Shooting Sports discipline and/or assisting on the range, a volunteer must meet the Florida 4-H youth ...
Julie Pigott Dillard, Heather C Kent, Julia S Kelly   +2 more
doaj   +1 more source

Private Clubs and Employment Discrimination: Does Federal Law Apply? [PDF]

, 1987
This Note examines the general history and function of Title VII and section 1981 of the civil rights law. The author discusses the problems inherent in defining an organization as a private club, for purposes of employment non-discrimination efforts ...
Hilton, Elyse
core   +1 more source

Football fans in training: the development and optimization of an intervention delivered through professional sports clubs to help men lose weight, become more active and adopt healthier eating habits [PDF]

, 2013
<p>Background: The prevalence of obesity in men is rising, but they are less likely than women to engage in existing weight management programmes.
A Bandura, A Chapple, A Pringle, A Pringle, AG Renehan, AJB Brady, Annie S Anderson, C Abraham, C Bye, C Duffin, C Emslie, Cancer Research UK, Cancer Research UK, CF Fitzsimons, Cindy M Gray, CJ Greaves, CM Gray, CM Gray, CM Gray, CM Gray, Counterweight Project Team, CS Carver, Department of Health Physical Activity, Health Improvement and Protection, E Manthou, ER Hirt, European Commission, Eurostat, G Baker, G McCartney, G O’Donovan, Government Office for Science, H Arksey, J Ritchie, J Wardle, Jim Leishman, K Daniel, K Hunt, K Jolly, K Witty, Kate Hunt, Lindsay Dalgarno, M Knowles, MD Young, N Priest, N Priest, NA King, Nanette Mutrie, National Institute for Health and Clinical Excellence, P Craig, P Morgan, PJ Morgan, R Williams, RE Glasgow, S Government, S Kuntsche, S Michie, S Michie, S Robertson, S Thomas, S Wyke, SA Jebb, Sally Wyke, Scottish Government, Scottish Premier League, SIG Network, SL Pagoto, T Calasanti, T Snow, W Hardeman   +68 more
core   +3 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source