Results 111 to 120 of about 5,090,387 (335)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Implementing a Work-Based Learning Approach to 4-H Camp Counseling

open access: yes, 2011
Although camping has been a successful 4-H delivery method, we believed a more intentional approach that viewed camp counseling as a job would allow teen camp counselors to connect skills they were learning with those needed for workforce success ...
T. Ferrari, Nate Arnett
semanticscholar   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Interdisciplinary use of film, video and computer graphics for representing architecture [PDF]

open access: yes, 1985
Thesis (M.S.V.S.)--Massachusetts Institute of Technology, Dept. of Architecture, 1985.MICROFICHE COPY AVAILABLE IN ARCHIVES AND ROTCHIncludes bibliographical references (leaves 68-69).This thesis examines the interdisciplinary application of film, video ...
Mark, Earl
core  

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

4-H Mindfulness Project Annotated Bibliography [PDF]

open access: yes, 2017
Author(s): Iaccopucci, Anne M; Lewis, Kendra M; Soule, Katherine E; Withrow-Clark, Robert | Abstract: The 4-H Healthy Living Initiative is focused on providing learning opportunities that address physical, social, and emotional health; the 4-H Mindfulness Project focuses on increasing youths’ ability to lead a healthy lifestyle and develop the skills ...
Iaccopucci, Anne M   +3 more
openaire   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Florida 4-H Cloverbud Project Report

open access: yesEDIS, 2023
The 4-H Cloverbud Project Summary is intended for youth ages 5–7 to complete at the completion of a 4-H educational project. This 7-page revision was compiled by the Florida 4-H Awards and Recognition Task Force; Geralyn Sachs and Laura Cash, chairs.
Laura Cash   +7 more
openaire   +2 more sources

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