Results 191 to 200 of about 5,090,387 (335)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

4-H and Youth Development: Music Project Guide

open access: green, 2002
Deborah A. Hall   +2 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Artificial Intelligence Search Tools for Evidence Synthesis: Comparative Analysis and Implementation Recommendations. [PDF]

open access: yesCochrane Evid Synth Methods
Featherstone R   +8 more
europepmc   +1 more source

Poultry management : for 4-H poultry projects

open access: green, 1952
E. B. Winner   +4 more
openalex   +1 more source

4-H Crop Projects 4: Soybeans and Corn—Fields of Opportunity

open access: green, 2004
Denise L. Schwab   +2 more
openalex   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Improving healthcare quality in Sudan: situation and factors influencing healthcare professionals' engagement. [PDF]

open access: yesBMC Health Serv Res
Elsharif SAM   +8 more
europepmc   +1 more source

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