Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan +11 more
wiley +1 more source
Building a Sexual and Reproductive Health Module for Implementation in Early Psychosis Programs: A Co-creation Process: Création d'un module sur la santé sexuelle et reproductive à mettre en œuvre dans les programmes d'intervention précoce en cas de psychose : un processus de création conjointe. [PDF]
Barker LC +17 more
europepmc +1 more source
Adhesion‐Driven Removal of Microplastics From Aquatic Systems by Using Microgel Glues
Soft polymeric microgels function as “glues” that aggregate diverse microplastics through multivalent adhesion, promoting their interfacial deposition and co‐precipitation for efficient removal from water. Remarkably, this approach remains effective even for nanoscale plastic particles as small as 50 nm.
Jinmeng Zhang +5 more
wiley +1 more source
Proper Personal Preparation for the 4-H Food Challenge Competition
This publication is a supplement to the Florida 4-H Food Challenge guides. Its purpose is to mimic the current food industry standards regarding proper personal hygiene and food preparation. This guide also includes a helpful checklist.
Jean Marie Arick +11 more
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De Novo assembly and analysis of the transcriptome of the Hyalomma anatolicum genes differentially expressed in normal morphology and disability. [PDF]
Zhang J +7 more
europepmc +1 more source
This study systematically reveals a complex interactive network involving plants, microbes, and insects, elucidating the ecological and molecular mechanisms by which cotton enhances its resistance to aphids through the active recruitment of the beneficial soil bacterium Delftia tsuruhatensis.
Hui Xue +11 more
wiley +1 more source
The Lang Youth Medical Program: a 6-year blueprint for advancing educational attainment and achievement. [PDF]
Ripple M +5 more
europepmc +1 more source
A supramolecular nanocomplex based on phenolic‐modified silk sericin is developed to deliver antioxidant enzymes across the blood–brain barrier and escape lysosomal degradation. This dual‐barrier‐crossing system reduces neuroinflammation and improves cognitive performance in Alzheimer's disease mouse model, offering a promising strategy for protein ...
Doudou Hu +5 more
wiley +1 more source
Editorial: Exploring life skills and positive youth development through sports. [PDF]
Muñoz-Llerena A +3 more
europepmc +1 more source
This study achieves the synergistic integration of self‐powered sensing and edge AI acceleration to establish a real‐time fault diagnosis system. The proposed TENG‐based self‐powered bearing sensor (NSE‐TBS) and FPGA‐accelerated edge AI framework fundamentally break through the inherent limitations of conventional monitoring systems, including complex ...
Kehui Zhu +7 more
wiley +1 more source

