Results 171 to 180 of about 98,427 (296)

CHARACTER EDUCATION AND 4-H YOUTH DEVELOPMENT

open access: yes, 2011
Character education assumes responsibility for influencing and educating youth on morals, values, beliefs and positive character attributes in order to influence them into being positive and contributing members of society.
Mullins, Jessica Lynn
core  

NIR‐II‐Trackable LYTACs Phyto‐Nanotheranostics for Source‐Microenvironment Dual‐Track ROS Regulation in Acute Gouty Arthritis

open access: yesAdvanced Science, EarlyView.
The TPR‐LYTACs nanomaterial offers a dual‐pathway strategy for precise gouty arthritis treatment by targeting and degrading the ROS‐producing enzyme NOX2 inside macrophages while its antioxidant core clears accumulated ROS outside. This “source inhibition and microenvironment scavenging” approach, guided by NIR‐II imaging, effectively controls local ...
Jian Zhang   +15 more
wiley   +1 more source

Leonurine Ameliorates Doxorubicin‐Induced Cardiotoxicity via STING/NF‐κB/NLRP3 Inflammasome Signaling Pathway

open access: yesAdvanced Science, EarlyView.
ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun   +10 more
wiley   +1 more source

Proper Personal Preparation for the 4-H Food Challenge Competition

open access: yesEDIS
This publication is a supplement to the Florida 4-H Food Challenge guides. Its purpose is to mimic the current food industry standards regarding proper personal hygiene and food preparation. This guide also includes a helpful checklist.
Jean Marie Arick   +11 more
doaj  

Forging Hopeful Futures Community-Partnered Violence Prevention Intervention: Protocol for a Comparative Effectiveness Trial. [PDF]

open access: yesJMIR Res Protoc
Culyba AJ   +17 more
europepmc   +1 more source

4-H leader's guide to handling funds in the 4-H youth development program.

open access: yes, 2014
Washington State University Extension 4-H Youth Development Program
core  

Multi‐Stimuli‐Responsive Hydrogen‐Bonded Organic Frameworks Nanocarriers Enable Targeted Fungicide Release and Plant Immune Regulation

open access: yesAdvanced Science, EarlyView.
A fluorinated hydrogen‐bonded organic framework nanocarrier (PFC‐1‐F) loaded with PYR and coated with HACC enables multi‐stimuli‐responsive (enzyme/ROS/pH) release at infection sites. Exhibiting targeted antifungal activity against Sclerotium rolfsii, modulating plant antioxidant defense, and demonstrating favorable biosafety across plant, soil, and ...
Guangming Ma   +6 more
wiley   +1 more source

Post-intensive care sequelae after severe bacterial infections in previously healthy children. [PDF]

open access: yesMol Cell Pediatr
Goretzki SC   +13 more
europepmc   +1 more source

Toward Nano‐Nutritional Medicine: A Remotely Activated Trans‐Vaccenic Acid‐Based Lipid Nanoparticles for Enhancing Immune Checkpoint Blockade Therapy

open access: yesAdvanced Science, EarlyView.
Eutectic mixtures from trans‐vaccenic acid (TVA) and stearic acid, which served as phase‐change material to encapsulate IR780, forming NIR‐responsive nanoparticles. IR780@TVA LNPs induce photothermal therapy and initiate adaptive anti‐tumor immunity.
Kang Liu   +12 more
wiley   +1 more source

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