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Targeting ALDH7A1 with covalent inhibitors reveals new chemical space for prostate cancer therapy. [PDF]
Gallo R +10 more
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Synthesis and Bioactivity Studies of Benzimidazole-Chalcone Hybrids. [PDF]
Makgoathana HD +4 more
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Conversion of N<sub>2</sub> into oxadiazoles promoted by a multinuclear samarium complex. [PDF]
Shi X, Yuan Q, Chen Y, Xi Z, Wei J.
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Foldamer-based K<sup>+</sup> channels with ion selectivity surpassing the KcsA channel. [PDF]
Lin Z +5 more
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An Overview: 1, 3, 4- oxadiazole and its uses
Asian Journal of Research in Chemistry, 2021Heterocyclic compounds show various potent biological activity. Every heterocyclic compound has different structure, different functional group and designed for different biological activities. Oxadiazole is one of those heterocyclic compounds possess various biological activity. The structure is simple contain carbon, nitrogen, oxygen, hydrogen.
Anuja S. Patil., Shrinivas K. Mohite
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[1, 2, 4]-Oxadiazoles: Synthesis and Biological Applications
Mini-Reviews in Medicinal Chemistry, 2014In the present article synthesis and medicinal applications of [1, 2, 4] oxadiazoles are reviewed. The oxadiazoles have a wide range of applications such as Antitussive, Anti-inflammatory, Anaesthetic, Vasodilator, anthelmintic, antiallergic, antiplatelet effects in vitro, antithrombotic properties in vivo, etc.
Rajesh O, Bora +3 more
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2, 5-Dialkyl-1, 3, 4-oxadiazoles
Chemistry of Heterocyclic Compounds, 1970A single stage method has been developed for the preparation of 2, 5-dialky-1, 3, 4-oxadiazoles from aliphatic carboxylic acids, by boiling with hydrazine hydrochloride in phosphoryl chloride. A mechanism for the synthesis is suggested. The oxadiazoles are characterized, and the group refractivity of the 1, 3, 4-oxadiazole ring has been determined.
M. S. Skorobogatova +2 more
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Synthesis of 1, 3, 4-Oxadiazole
Asian Journal of Research in Chemistry, 2017Synthesis of 1, 3, 4-oxadiazole by the reaction of 2-propyl Benzo imidiazol-2-yl carbohydrazide and 1, 3, dihydro iso indo-2-yl acetic acid (Phthalyl Amino Acids) in presence of HCl and phosphoryl chloride. All the newly synthesized compounds were screened antibacterial activity which shows moderate to mild activity, and yield of the synthesized ...
Maqdoom Farooqui, Syed Nazimuddin
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