Results 171 to 180 of about 9,301,702 (224)

Targeting ALDH7A1 with covalent inhibitors reveals new chemical space for prostate cancer therapy. [PDF]

open access: yesJ Enzyme Inhib Med Chem
Gallo R   +10 more
europepmc   +1 more source

Synthesis and Bioactivity Studies of Benzimidazole-Chalcone Hybrids. [PDF]

open access: yesMolecules
Makgoathana HD   +4 more
europepmc   +1 more source

<i>One-pot</i> dearomatizative telescoped addition of <i>C</i>-nucleophiles to fluorinated 1,2,4-oxadiazoles followed by regioselective <i>N</i>-functionalization.

open access: yesOrg Chem Front
Castiglione D   +9 more
europepmc   +1 more source
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An Overview: 1, 3, 4- oxadiazole and its uses

Asian Journal of Research in Chemistry, 2021
Heterocyclic compounds show various potent biological activity. Every heterocyclic compound has different structure, different functional group and designed for different biological activities. Oxadiazole is one of those heterocyclic compounds possess various biological activity. The structure is simple contain carbon, nitrogen, oxygen, hydrogen.
Anuja S. Patil., Shrinivas K. Mohite
openaire   +1 more source

[1, 2, 4]-Oxadiazoles: Synthesis and Biological Applications

Mini-Reviews in Medicinal Chemistry, 2014
In the present article synthesis and medicinal applications of [1, 2, 4] oxadiazoles are reviewed. The oxadiazoles have a wide range of applications such as Antitussive, Anti-inflammatory, Anaesthetic, Vasodilator, anthelmintic, antiallergic, antiplatelet effects in vitro, antithrombotic properties in vivo, etc.
Rajesh O, Bora   +3 more
openaire   +2 more sources

2, 5-Dialkyl-1, 3, 4-oxadiazoles

Chemistry of Heterocyclic Compounds, 1970
A single stage method has been developed for the preparation of 2, 5-dialky-1, 3, 4-oxadiazoles from aliphatic carboxylic acids, by boiling with hydrazine hydrochloride in phosphoryl chloride. A mechanism for the synthesis is suggested. The oxadiazoles are characterized, and the group refractivity of the 1, 3, 4-oxadiazole ring has been determined.
M. S. Skorobogatova   +2 more
openaire   +1 more source

Synthesis of 1, 3, 4-Oxadiazole

Asian Journal of Research in Chemistry, 2017
Synthesis of 1, 3, 4-oxadiazole by the reaction of 2-propyl Benzo imidiazol-2-yl carbohydrazide and 1, 3, dihydro iso indo-2-yl acetic acid (Phthalyl Amino Acids) in presence of HCl and phosphoryl chloride. All the newly synthesized compounds were screened antibacterial activity which shows moderate to mild activity, and yield of the synthesized ...
Maqdoom Farooqui, Syed Nazimuddin
openaire   +1 more source

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