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Antimicrobial Activity of 1,3,4-Oxadiazole Derivatives [PDF]
International Journal of Molecular Sciences, 2021 The worldwide development of antimicrobial resistance forces scientists to search for new compounds to which microbes would be sensitive. Many new structures contain the 1,3,4-oxadiazole ring, which have shown various antimicrobial activity, e.g., antibacterial, antitubercular, antifungal, antiprotozoal and antiviral. In many publications, the activity
Teresa Glomb, Piotr Świątek
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An Understanding of Mechanism-Based Approaches for 1,3,4-Oxadiazole Scaffolds as Cytotoxic Agents and Enzyme Inhibitors [PDF]
Pharmaceuticals, 2023 The world’s health system is plagued by cancer and a worldwide effort is underway to find new drugs to treat cancer. There has been a significant improvement in understanding the pathogenesis of cancer, but it remains one of the leading causes of death ...
Davinder Kumar +6 more
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Synthesis and in vitro antibacterial activity of new oxoethylthio-1,3,4-oxadiazole derivatives
Journal of Saudi Chemical Society, 2014 In the present investigation, a series of 2(4-pyridyl)-5[(aryl/heteroarylamino)-1-oxoethyl]thio-1,3,4-oxadiazole were synthesized using isonicotinohydrazide and substituted aryl/heteroaryl amines using pyridine as solvent.
Jignesh P Raval
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Anti-Cancer Activity of Derivatives of 1,3,4-Oxadiazole
Molecules, 2018 Compounds containing 1,3,4-oxadiazole ring in their structure are characterised by multidirectional biological activity. Their anti-proliferative effects associated with various mechanisms, such as inhibition of growth factors, enzymes, kinases and ...
Teresa Glomb, Piotr Świątek
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Research progress on the synthesis and pharmacology of 1,3,4-oxadiazole and 1,2,4-oxadiazole derivatives: a mini review [PDF]
Journal of Enzyme Inhibition and Medicinal Chemistry, 2022 Wang JJ, Sun W, Jia WD, Bian M, Yu LJ.
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Journal of Applied Pharmaceutical Research, 2022 A class of innovative benzimidazole-1,3,4-Oxadiazole derivatives is a significant heterocyclic molecule for therapeutic development. In heterocyclic chemistry, the novel 1,3,4-Oxadiazole nucleus has a wide range of uses, including antibacterial ...
Shivanand Kolageri +2 more
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Synthesis and characterization of new phthalimides and succinimides substituted with 1,3,4-oxadiazole ring [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2012 A series of new phthalimides and succinimides connected to 1,3,4-oxadiazole moiety were synthesized via multistep synthesis. The first step involved synthesis of six 5- substituted 2- amino-1,3,4-oxadiazoles by oxidative cyclization of substituted ...
Ahlam Marouf Al-Azzawi +1 more
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Synthesis and characterization of 5-aryl-1,3,4-oxadiazole-2(3h)thione derivatives
Journal of Applied Pharmaceutical Research, 2020 1,3,4-oxadiazoles represent a class of heterocyclic five membered compounds it contain two nitrogen and one oxygen of great importance in Pharmaceutical chemistry. This nucleus show four isomeric forms 1,2,4-oxadiazole,1,3,4-oxadiazole, 1,2,5-oxadiazole,
Shailesh Pathak +3 more
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Therapeutic potential of oxadiazole or furadiazole containing compounds
BMC Chemistry, 2020 As we know that, Oxadiazole or furadi azole ring containing derivatives are an important class of heterocyclic compounds. A heterocyclic five-membered ring that possesses two carbons, one oxygen atom, two nitrogen atoms, and two double bonds is known as ...
Ankit Siwach, Prabhakar Kumar Verma
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Acta Crystallographica Section E: Crystallographic Communications, 2023 The title compounds were synthesized by alkylation of 5-[(4-dimethylamino)phenyl]-1,3,4-oxadiazole-2-thiol with benzyl chloride or 2-chloro-6-fluorobenzyl chloride in the presence of potassium carbonate.
Rasul Ya. Okmanov +4 more
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