Investigation on Quantitative Structure-Activity Relationships of 1,3,4 Oxadiazole Derivatives as Potential Telomerase Inhibitors [PDF]
The published manuscript is available at EurekaSelect via http://www.eurekaselect.com/164022/article, DOI : 10.2174/1570163815666180724113208. © 2018 Bentham ScienceA series of 1,3,4-oxadiazole derivatives with significant broad-spectrum anticancer ...
Almerico, Anna Maria +2 more
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N-Phenyl-N-{4-[5-(4-pyridyl)-1,3,4-oxadiazol-2-yl]phenyl}aniline
The title compound, C25H18N4O, is a non-planar bipolar ligand containing triphenylamine and 1,3,4-oxadiazole units. In the molecule, the benzene ring, the 1,3,4-oxadiazole ring, and the pyridine ring are twisted slightly with respect to each other ...
Li-Ping Han, Bin Li, Jie Liu
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Chemotherapy is an important therapeutic approach for the treatment of cancer. Currently, many anticancer drugs are available in the market that plays an important role in cancer treatment, but concerns such as, drug resistance and side effects create an
Swarnagowri Nayak +3 more
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SYNTHESIS,ANTIBACTERIAL ACTIVITY OF 2-AMINO 5-PHENYL -1,3,4- OXADIAZOLE DERIVATIVES
In the present investigation, five derivatives were synthesized as potential antimicrobial agents , The compounds are : 2-amino 5-phenyl - 1,3,4- oxadiazole dithi-ocarbomate, 2-amino 5-( 4-amino- N,N-dimethyl phenyl)- 1,3,4- oxadiazole, 2 ...
Hussain jassem Mohammed
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Two reaction routes for the preparation of aromatic polyoxadiazoles and polytriazoles: Syntheses and properties [PDF]
Two reaction routes for the preparation of aromatic poly-1,3,4-oxadiazoles and poly-1,2,4-triazoles are studied and their influence on the physical properties, i.e., inherent viscosity, glass transition, degradation temperature, and film integrity of the
Boom, J.P. +6 more
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The presence of heterocyclic structures in diverse types of compounds, this is strongly indicative of the profound effect like structure exerts on physiologic activity, and recognition of this is abundantly reflected in efforts to find useful synthetic ...
Dilipkumar Pal +3 more
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Synthesis of some substituted 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles from 2-(2,3-dimethylphenyl amino) benzoic acid [PDF]
In this paper the synthesis of some substituted 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles was achieved. 2-(2,3-dimethyl phenyl amino) benzoic acid was esterified to its ethyl ester by its reaction with absolute ethanol in presence of ...
Khalid Daoud +2 more
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Synthesis and Antimicrobial Screening of Some New Thiazole Substituted 1,3,4-Oxadiazole Derivatives
In the present work, the synthesis and antimicrobial activity of new thiazole substituted 1,3,4-oxadiazole derivatives was achieved. The reaction of different thioamides with ethyl 4-chloro-3-oxobutanoate (4-chloro ethyl acetoacetate) provided ethyl 2-(2-
Siddhant V. Kokate, Sachin V. Patil
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Study on the synthesis of novel 5-substituted 2-[2-(pyridyl)ethenyl]-1,3,4-oxadiazoles and their acid–base interactions [PDF]
: A series of novel 5-substituted 2-[2-(pyridyl)ethenyl]-1,3,4-oxadiazoles were efficiently synthesized by cyclocondensation of the appropriate 3-(pyridyl)acrylohydrazides with triethyl orthoesters in the presence of glacial acetic acid.
Agnieszka Kudelko +2 more
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Synthesis and Characterization of 1,3,4-Oxadiazoles Derived From 9-Fluorenone
In the present work, 9-fluorenone-2-carboxylic acid methyl ester (1) was prepared from 9-fluorenone-2-carboxylic acid and then converted into the acid hydrazide (2).
Baghdad Science Journal
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