Results 1 to 10 of about 1,474 (179)

SYNTHESIS OF SOME 1,3,4- OXADIAZOLES FROM ETHYL IMIDAZO [4,5-B] PYRIDINYL PROPIONATE AS PONTENTIAL ANTIINFLAMMATORY AGENTS

open access: yesZagazig Journal of Pharmaceutical Sciences, 1993
Synthesis of 2- (6-bromo -2- imidazo [4,5-b] pyridinyl) ethyl -5-( substituted) thío 1,3,4 Oxadiazole derivatives is described. The preparation of 1,3,4 - Oxadiazoles was achieved by cyclization of the corresponding acid hydrazide.
Mohamed Ebeid   +4 more
doaj   +1 more source

Synthesis a Number of Heterocyclic Compounds and some of chalcones Derived From Levofloxacin

open access: yesTikrit Journal of Pure Science, 2023
The hydrazide (1) was used as synthone for the following Compound pyridazine-3,6-dione (2) by reaction of hydrazide (1) with maleic  anhydride and Compound phthalazine-1,4-dione (3) by the reaction of  hydrazide (1) with phthalic anhydride.
Ekram Abdullah Basheer   +2 more
doaj   +1 more source

SYNTHESIS OF MONO-SUBSTITUTED AND SIMMETRICALLY 2, 5-DISUBSTITUTED 1, 3, 4-OXADIAZOLES [PDF]

open access: yesChemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2012
In recent years 1,3,4-oxadiazoles have received considerable attention due to their wide range of biological activities and practical importance. They form an important class of fi ve-member heterocyclic compounds with a variety of derivatives.
Z. Ribcovskaia, F. Macaev
doaj  

Synthesis of 1,3,4-Oxadiazole Derivatives from Ethyl-2-Piperidone-3-Carboxylate [PDF]

open access: yesمجلة التربية والعلم, 2012
In the present work, some new 1,3,4- Oxadiazole derivatives have been synthesized from Ethyl-2-Piperidone-3-Carboxylate. The reaction of the ethyl ester with hydrazine hydrate afforded the corresponding hydrazide (I).
M. A. Sheat, O. I. Mohammed
doaj   +1 more source

Synthesis, Characterization and Biological Investigation of Some New Hydroxy – 1,3,4 – Oxadiazole Derivatives [PDF]

open access: yesKirkuk Journal of Science, 2016
study the solid compounds of hydroxy 1,3,4 – oxadiazoles have been synthesized by reaction of acid hydrazides with CS2 in the presence of KOH.
Afraa S. S, Jawdat H. A
doaj   +1 more source

Syntheses, Evaluation and Characterization of Some 1, 3, 4-Oxadiazoles as Antimicrobial Agents

open access: yesE-Journal of Chemistry, 2009
1,3,4-Oxadiazoles show various biological activities and have been synthesized from different compounds. 1,3,4-oxadiazole is popularly known for its antimicrobial, anti-inflammatory, pesticidal and antihypertensive activities etc.
Niti Bhardwaj   +3 more
doaj   +1 more source

Synthesis of some substituted 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles from 2-(2,3-dimethylphenyl amino) benzoic acid [PDF]

open access: yesمجلة التربية والعلم, 2009
In this paper the synthesis of some substituted 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles was achieved. 2-(2,3-dimethyl phenyl amino) benzoic acid was esterified to its ethyl ester by its reaction with absolute ethanol in presence of ...
Khalid Daoud   +2 more
doaj   +1 more source

Arylation Reactions in the Synthesis of Biologically Important 2,5-Diaryl-1,3,4-Oxadiazoles

open access: yesApplied Sciences, 2022
Apart from carbon atoms, some cyclic molecules contain other elements and play an extraordinary role in human life. Among these systems, 1,3,4-oxadiazole derivatives deserve special attention due to their biological properties such as antibacterial ...
Monika Olesiejuk, Agnieszka Kudelko
doaj   +1 more source

Syntheses of Diheterocyclic Compounds Based on 2-Thioacetohydrazide-5,7-dimethyl-1,2,4-triazolo[1,5-a]- pyrimidine

open access: yesMolecules, 2008
The syntheses of some diheterocyclic compounds from 2-thioacetohydrazide- 5,7-dimethyl-1,2,4-triazolo[1,5-a]pyrimidine (1) are described. Compound 1 can be converted into triazoles, 1,3,4-oxadiazoles, and 1,3,4-thiadiazoles.
Guang-Fu Yang   +4 more
doaj   +1 more source

Tyrosinase Inhibitory Activity, 3D QSAR, and Molecular Docking Study of 2,5-Disubstituted-1,3,4-Oxadiazoles

open access: yesJournal of Chemistry, 2013
In continuation with our research program, in search of potent enzyme tyrosinase inhibitor, a series of synthesized 2,5-disubstituted 1,3,4-oxadiazoles have been evaluated for enzyme tyrosinase inhibitory activity.
Ramesh L. Sawant   +2 more
doaj   +1 more source

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