Results 1 to 10 of about 950 (182)

Synthesis of Some substituted (Pyrazolines) Derived From Benzotriazole [PDF]

Kirkuk Journal of Science, 2016
In this paper , a number of heterocyclic compounds with five-memberd pyrazolines were prepared , the ester compound (1) was synthesized from the reaction of benzotriazole with ethyl chloroacetate , the hydrazide (2) was prepared from the reaction of ...
Fariq Salah Ahmed, Ayad S. Hameed, Khalid M. Mohammed   +2 more
doaj   +1 more source

Eco-Friendly Synthesis, Characterization and Biological Evaluation of Some Novel Pyrazolines Containing Thiazole Moiety as Potential Anticancer and Antimicrobial Agents

Molecules, 2018
The one-pot synthesis of a series of pyrazoline derivatives containing the bioactive thiazole ring has been performed through a 1,3-dipolar cycloaddition reaction of N-thiocarbamoylpyrazoline and different hydrazonoyl halides or α-haloketones in the
Mastoura M. Edrees, Sraa Abu- Melha, Amirah M. Saad, Nabila A. Kheder, Sobhi M. Gomha, Zeinab A. Muhammad   +5 more
doaj   +1 more source

Synthesis and Crystal Structures of 4,5-Dihydroimidazo[1,5-b]pyrazol-6-ones

SynOpen, 2020
The synthesis of previously unattainable 2,5-disubstituted 4,5-dihydroimidazo[1,5-b]pyrazol-6-ones has been developed. Electrochemical reductions of readily available 2,2,2-trichloroethylideneacetophenones were followed by reaction with hydrazine ...
Antonio Guirado, María Vera, Bruno Martiz, Francisco Ródenas, José A. Sandoval, Enrique Alarcón, Delia Bautista   +6 more
doaj   +1 more source

Synthesis of a novel series of chalcones and pyrazolines, possessing indole with 4-(2,2,2-trifluroethoxy) pyridine moiety

Orbital: The Electronic Journal of Chemistry, 2012
A new method for the construction of novel fluorine-containing indole ring system has been reported. These indoles were converted into a new series of fluorine-containing indolyl chalcones (1a-g) and pyrazolines (2a-g). All the newly synthesized
Mazahar Farooqui, Nasir Ali Shafakat Ali, Afzal Yosuf Khan   +2 more
doaj   +1 more source

(E)-(1-(4-Ethoxycarbonylphenyl)-5-(3,4-dimethoxyphenyl)-3-(3,4-dimethoxystyryl)-2-pyrazoline: Synthesis, Characterization, DNA-Interaction, and Evaluation of Activity Against Drug-Resistant Cell Lines

Molbank, 2020
(E)-1-(4-Ethoxycarbonylphenyl)-5-(3,4-dimethoxyphenyl)-3-(3,4-dimethoxystyryl)-2-pyrazoline was synthesized via the cyclization reaction between the monocarbonyl curcuminoid (2E,6E)-2,6-bis(3,4-dimethoxybenzylidene)acetone and ethyl hydrazinobenzoate in ...
Dimitris Matiadis, Barbara Mavroidi, Angeliki Panagiotopoulou, Constantinos Methenitis, Maria Pelecanou, Marina Sagnou   +5 more
doaj   +1 more source

Synthesis of New Pyrazolines Derivatives from Coumarine Compounds [PDF]

مجلة التربية والعلم, 1999
The present work includes preparation of series of chalcones and condensation of these chalcones with a series of prepared coumarin hydrazides in acidic medium to afford the new pyrazolines.
W. Gh-Bedewy, O. Salih, A. Ahmad
doaj   +1 more source

Synthesis, biological evaluation and molecular docking of methoxy

Pakistan Journal of Pharmaceutical Sciences, 2022
This research aims to synthesize some N-phenylpyrazoline derivatives with methoxy substituents and study their activity as potent anticancer agents as well as their interaction with the EGFR receptor on cancer cells.
Setiawati, Artania Adnin Tri Suma, Yoeretisa Miggia Stansyah, Endang Astuti Sekip Utara BLS, Yogyakarta, Indonesia   +5 more
doaj   +1 more source

Cytotoxic potential of novel N-formyl pyrazolines derived from vanillin [PDF]

Kragujevac Journal of Science
In the reaction of vanillin and acetone under Claisen-Schmidt conditions, dehydrozingerone, a very attractive biologically active compound, is obtained.
Muškinja Jovana M., Marković Violeta R., Todorović Tamara Lj, Luković Jovan D., Nikolić Ivana S., Mitrović Marina M., Ratković Zoran R.   +6 more
doaj   +1 more source

Pyrazoline derivatives as promising novel antischistosomal agents

Scientific Reports, 2021
Praziquantel is the only available drug to treat schistosomiasis, a parasitic disease that currently infects more than 240 million people globally. Due to increasing concerns about resistance and inadequate efficacy there is a need for new therapeutics ...
Cristiane S. Morais, Ana C. Mengarda, Fábio B. Miguel, Karine B. Enes, Vinícius C. Rodrigues, Maria Cristina C. Espírito-Santo, Abolghasem Siyadatpanah, Polrat Wilairatana, Mara R. C. Couri, Josué de Moraes   +9 more
doaj   +1 more source

Synthesis and in Vitro Antimicrobial Activity of Some Pyrazolyl-1-carboxamide Derivatives

Molecules, 2011
A series of 3,5-disubstituted pyrazole-1-carboxamides were obtained by treatment of chalcones with semicarbazide hydrochloride in dioxane containing sodium acetate/acetic acid as a buffer solution.
Essam Mohamed Sharshira, Nagwa Mohamed Mahrous Hamada   +1 more
doaj   +1 more source