Results 21 to 30 of about 950 (182)

Design, Synthesis, and In Vitro Evaluation of Novel Indolyl DiHydropyrazole Derivatives as Potential Anticancer Agents

open access: yesMolecules, 2021
Indoles derived from both natural sources or artificial synthetic methods have been known to interact with aryl hydrocarbon receptors (AhR), and exhibit anticancer activity.
Katharigatta N. Venugopala   +3 more
doaj   +1 more source

Synthesis of novel pyrazoline based bis (1,2,3-triazole) scaffolds via click chemistry [PDF]

open access: yesJournal of the Serbian Chemical Society, 2017
A series of novel bis(1,2,3-triazoles) derivatives 7a–m were synthesized by the 1,3-dipolar cycloaddition (click-reaction) of 1-methyl-3,5-bis(2- -(prop-2-yn-1-yloxy)phenyl)-4,5-dihydro-1H-pyrazole (5) with various aralkyl azides 6a–m in the presence of ...
Kiran Kothuri   +4 more
doaj   +1 more source

Synthesis

open access: yesBulletin of Faculty of Pharmacy Cairo University, 2013
Driven by the increased demand of pyrazolines exhibiting biological activities like antioxidant, anti-inflammatory, antidepressant, antimicrobial, antitumor, and antitubercular drug activity as a stable fragment in biological moieties, lead us to ...
Akshay Kumar   +2 more
doaj   +1 more source

Synthesis, Characterization and Biological Evaluation of New 3,5-Disubstituted-Pyrazoline Derivatives as Potential Anti-Mycobacterium tuberculosis H37Ra Compounds

open access: yesMolecules, 2021
A total of fourteen pyrazoline derivatives were synthesized through cyclo-condensation reactions by chalcone derivatives with different types of semicarbazide.
Kok Tong Wong   +5 more
doaj   +1 more source

Synthesis, antimicrobial and antitubercular activities of some novel pyrazoline derivatives

open access: yesJournal of Saudi Chemical Society, 2016
In the present study, two new series of pyrazolines (3a–h & 4a–h) were synthesized starting from p-acetamidophenol (paracetamol) and evaluated for their antibacterial, antifungal and antitubercular activities.
Aftab Ahmad   +4 more
doaj   +1 more source

1-[5-(3,5-Dimethoxyphenyl)-3-(2-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]ethanone

open access: yesIUCrData, 2021
In the title compound, C20H22N2O4, two benzene rings bearing methoxy substituents are connected by a central acetylpyrazoline ring: the dihedral angle between the benzene rings is 83.7 (1)°.
Miri Yoo, Dongsoo Koh
doaj   +1 more source

Hybridization of Thiazole and Pyrazoline heterocycles, and the Biological Activities of Their Hybrid Scaffolds [PDF]

open access: yesERU Research Journal
Thiazoles and pyrazolines represent a class of heterocyclic compounds with attractive and considerable interest in medicinal chemistry due to their diverse pharmacological activities.
Mariam Fakhry, Amr Mattar
doaj   +1 more source

Green Synthesis and In Vitro Biological Evaluation of Heteroaryl Chalcones and Pyrazolines of Medicinal Interest

open access: yesJournal of Chemistry, 2013
Pyrazolines are well known and important nitrogen containing 5-membered heterocyclic compounds. In the present investigation, a series of various heteroaryl chalcones and pyrazolines were synthesized by condensing formylquinolines with diverse ketones ...
Vishal Banewar
doaj   +1 more source

Microwave assisted synthesis of substituted 4-chloro-8-methyl-2-(1,3-diphenyl-1H-pyrazol-4-yl)-1,5-dioxa-2H-phenanthren-6-ones and their antimicrobial activity [PDF]

open access: yesJournal of the Serbian Chemical Society, 2017
Due to the potential antimicrobial activity of pyranochromenones and pyrazolines moieties, hybrid compounds containing both, substituted 4-Chloro-8-methyl-2-(1,3-diphenyl- -1H-pyrazol-4-yl)-1,5-dioxa-2H-phenanthren-6-ones (4a-g), have been ...
Ashok Dongamanti   +3 more
doaj   +1 more source

Investigation of Pyrazoline-Based Aromatic Sulfamates as Carbonic Anhydrase Isoforms I, II, IX, and XII Inhibitors

open access: yesMedical Sciences Forum, 2022
Four new series of aromatic sulfamates were synthesized and investigated for the inhibition of four human (h) isoforms of zinc enzyme carbonic anhydrase, hCA I, II, IX, and XII.
Davide Moi
doaj   +1 more source

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