Results 21 to 30 of about 4,154 (224)

Synthesis, antimicrobial and antitubercular activities of some novel pyrazoline derivatives

open access: yesJournal of Saudi Chemical Society, 2016
In the present study, two new series of pyrazolines (3a–h & 4a–h) were synthesized starting from p-acetamidophenol (paracetamol) and evaluated for their antibacterial, antifungal and antitubercular activities.
Aftab Ahmad   +4 more
doaj   +1 more source

1-[5-(3,5-Dimethoxyphenyl)-3-(2-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]ethanone

open access: yesIUCrData, 2021
In the title compound, C20H22N2O4, two benzene rings bearing methoxy substituents are connected by a central acetylpyrazoline ring: the dihedral angle between the benzene rings is 83.7 (1)°.
Miri Yoo, Dongsoo Koh
doaj   +1 more source

Chalcones as versatile synthons for the synthesis of 5- and 6-membered nitrogen heterocylces [PDF]

open access: yes, 2014
Chalcones belong to the flavonoid family which constitutes one of the major classes of naturally occurring oxygen heterocyclic compounds. The alpha,beta-unsaturated carbonyl system of chalcones possesses two electrophilic reactive centers allowing them ...
Albuquerque, Hélio   +3 more
core   +1 more source

Synthesis and tautomerism of spiro-pyrazolines [PDF]

open access: yesTetrahedron Letters, 2014
An experimental study on the synthesis, tautomerism and acid promoted structural changes of spiro-pyrazolines is described. The target was achieved through a [3+2]-dipolar cycloaddition of an alkene with nitrile imines generated in situ and was isolated in high yield.
Sureshbabu, Dadiboyena   +2 more
openaire   +2 more sources

Microwave assisted synthesis of substituted 4-chloro-8-methyl-2-(1,3-diphenyl-1H-pyrazol-4-yl)-1,5-dioxa-2H-phenanthren-6-ones and their antimicrobial activity [PDF]

open access: yesJournal of the Serbian Chemical Society, 2017
Due to the potential antimicrobial activity of pyranochromenones and pyrazolines moieties, hybrid compounds containing both, substituted 4-Chloro-8-methyl-2-(1,3-diphenyl- -1H-pyrazol-4-yl)-1,5-dioxa-2H-phenanthren-6-ones (4a-g), have been ...
Ashok Dongamanti   +3 more
doaj   +1 more source

Green Synthesis and In Vitro Biological Evaluation of Heteroaryl Chalcones and Pyrazolines of Medicinal Interest

open access: yesJournal of Chemistry, 2013
Pyrazolines are well known and important nitrogen containing 5-membered heterocyclic compounds. In the present investigation, a series of various heteroaryl chalcones and pyrazolines were synthesized by condensing formylquinolines with diverse ketones ...
Vishal Banewar
doaj   +1 more source

Investigation of Pyrazoline-Based Aromatic Sulfamates as Carbonic Anhydrase Isoforms I, II, IX, and XII Inhibitors

open access: yesMedical Sciences Forum, 2022
Four new series of aromatic sulfamates were synthesized and investigated for the inhibition of four human (h) isoforms of zinc enzyme carbonic anhydrase, hCA I, II, IX, and XII.
Davide Moi
doaj   +1 more source

Asymmetric 1,3-dipolar cycloadditions of acrylamides [PDF]

open access: yes, 2009
This critical review, which is relevant to researchers in synthetic organic chemistry, focuses on asymmetric 1,3-dipolar cycloadditions with acrylamides.
Kissane, Marie, Maguire, Anita R.
core   +1 more source

Synthesis, spectral characterization and biological evaluation of 1-thiocarbamoyl-3-phenyl-5-hydroxy-5-(-2-pyridyl)-4-pyrazolines via Michael addition

open access: yesJournal of Saudi Chemical Society, 2016
A series of 1-thiocarbamoyl-3-phenyl-5-hydroxy-5-(2-pyridyl)-4-pyrazolines derivatives have been synthesized using sodium acetate as a catalyst. The spectral characterization and structure of 1-thiocarbamoyl-3-phenyl-5-hydroxy-5-(2-pyridyl)-4-pyrazolines
D. Chinnaraja   +3 more
doaj   +1 more source

Synthesis of Non-Racemic Pyrazolines and Pyrazolidines by [3+2] Cycloadditions of Azomethine Imines

open access: yesMolecules, 2017
Asymmetric [3+2] cycloadditions of azomethine imines comprise a useful synthetic tool for the construction of pyrazole derivatives with a variable degree of saturation and up to three stereogenic centers.
Franc Požgan   +4 more
doaj   +1 more source

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