Results 21 to 30 of about 929 (177)

Green Synthesis and In Vitro Biological Evaluation of Heteroaryl Chalcones and Pyrazolines of Medicinal Interest

open access: yesJournal of Chemistry, 2013
Pyrazolines are well known and important nitrogen containing 5-membered heterocyclic compounds. In the present investigation, a series of various heteroaryl chalcones and pyrazolines were synthesized by condensing formylquinolines with diverse ketones ...
Vishal Banewar
doaj   +1 more source

Microwave assisted synthesis of substituted 4-chloro-8-methyl-2-(1,3-diphenyl-1H-pyrazol-4-yl)-1,5-dioxa-2H-phenanthren-6-ones and their antimicrobial activity [PDF]

open access: yesJournal of the Serbian Chemical Society, 2017
Due to the potential antimicrobial activity of pyranochromenones and pyrazolines moieties, hybrid compounds containing both, substituted 4-Chloro-8-methyl-2-(1,3-diphenyl- -1H-pyrazol-4-yl)-1,5-dioxa-2H-phenanthren-6-ones (4a-g), have been ...
Ashok Dongamanti   +3 more
doaj   +1 more source

Investigation of Pyrazoline-Based Aromatic Sulfamates as Carbonic Anhydrase Isoforms I, II, IX, and XII Inhibitors

open access: yesMedical Sciences Forum, 2022
Four new series of aromatic sulfamates were synthesized and investigated for the inhibition of four human (h) isoforms of zinc enzyme carbonic anhydrase, hCA I, II, IX, and XII.
Davide Moi
doaj   +1 more source

Synthesis and tautomerism of spiro-pyrazolines [PDF]

open access: yesTetrahedron Letters, 2014
An experimental study on the synthesis, tautomerism and acid promoted structural changes of spiro-pyrazolines is described. The target was achieved through a [3+2]-dipolar cycloaddition of an alkene with nitrile imines generated in situ and was isolated in high yield.
Sureshbabu, Dadiboyena   +2 more
openaire   +2 more sources

Synthesis, spectral characterization and biological evaluation of 1-thiocarbamoyl-3-phenyl-5-hydroxy-5-(-2-pyridyl)-4-pyrazolines via Michael addition

open access: yesJournal of Saudi Chemical Society, 2016
A series of 1-thiocarbamoyl-3-phenyl-5-hydroxy-5-(2-pyridyl)-4-pyrazolines derivatives have been synthesized using sodium acetate as a catalyst. The spectral characterization and structure of 1-thiocarbamoyl-3-phenyl-5-hydroxy-5-(2-pyridyl)-4-pyrazolines
D. Chinnaraja   +3 more
doaj   +1 more source

Synthesis and Pharmacological Evaluation of Some Phenylpyrazolo Indoquinoxaline Derivatives

open access: yesE-Journal of Chemistry, 2011
Indoloquinoxalin was fused with 2,3 diphenyl quinoxaline by a methylene bridge which was then allowed for acetylation. The acetylated product was made to react with different aromatic aldehydes to give chalcones.
CH. Sridevi, K. Balaji, A. Naidu
doaj   +1 more source

Synthesis of Non-Racemic Pyrazolines and Pyrazolidines by [3+2] Cycloadditions of Azomethine Imines

open access: yesMolecules, 2017
Asymmetric [3+2] cycloadditions of azomethine imines comprise a useful synthetic tool for the construction of pyrazole derivatives with a variable degree of saturation and up to three stereogenic centers.
Franc Požgan   +4 more
doaj   +1 more source

Synthesis, crystal structure and Hirshfeld surface analysis of 4-[3-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-5-yl]-2-methoxyphenol monohydrate

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2019
In the title pyrazoline derivative, C16H16N2O3·H2O, the pyrazoline ring has an envelope conformation with the substituted sp2 C atom on the flap. The pyrazoline ring makes angles of 86.73 (12) and 13.44 (12)° with the trisubstituted and disubstituted ...
Linh Duong Khanh   +5 more
doaj   +1 more source

Design, Synthesis, and Anti-mycobacterial Evaluation of New 3,5-Disubstituted-pyrazole-1-carbothioamides

open access: yesIndonesian Journal of Chemistry, 2022
Two series of new 3,5-disubstituted-pyrazole-1-carbothioamides (4a-f and 5a-e) were designed and synthesized through condensation reaction between chalcones and thiosemicarbazides under alkaline condition via cyclocondensation reaction.
Kok Tong Wong   +6 more
doaj   +1 more source

THE TAUTOMERISM OF PYRAZOLINES (DIHYDROPYRAZOLES) [PDF]

open access: yesJournal of the Chilean Chemical Society, 2015
The exception to the rule that Δ3-pyrazolines are not stable unless both nitrogen atoms are substituted that has been recently published, Tetrahedron Lett. 55, 2208, (2014), has been proved false. By means of GIAO/B3LYP/6-311++G(d,p) calculations, it has been shown that the product is a pyrazole formed by rearrangement.
ALKORTA, I, ELGUERO, J
openaire   +2 more sources

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