Results 1 to 10 of about 10,638 (220)

The geroprotective potential of chalcones. [PDF]

Nat Commun
Abstract Aging is the most important risk factor for multiple pathologies including cardiovascular, neoplastic, metabolic and neurodegenerative diseases. Potential geroprotective strategies involve lifestyle-related, nutritional and pharmacological interventions.
Carmona-Gutierrez D, Zimmermann A, Kroemer G, Madeo F.   +3 more
europepmc   +4 more sources

The solubility and stability of heterocyclic chalcones compared with trans-chalcone [PDF]

Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials, 2020
Heterocyclic chalcones are a recently explored subgroup of chalcones that have sparked interest due to their significant antibacterial and antifungal capabilities. Herein, the structure and solubility of two such compounds, (E)-1-(1H-pyrrol-2-yl)-3-(thiophen-2-yl)prop-2-en-1-one and (E)-3-phenyl-1-(1H-pyrrol-2-yl)prop-2-en-1-one, are assessed.
Stephen G. Sweeting, Charlie L. Hall, Jason Potticary, Natalie E. Pridmore, Stephen D. Warren, Matthew E. Cremeens, Gemma D. D'Ambruoso, Masaomi Matsumoto, Simon R. Hall   +8 more
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Identification and Functional Characterization of Fungal Chalcone Synthase and Chalcone Isomerase

Journal of Natural Products, 2023
By mining fungal genomic information, a noncanonical iterative type I PKS fused with an N-terminal adenylation-thiolation didomain, which catalyzes the formation of naringenin chalcone, was found. Structural prediction and molecular docking analysis indicated that a C-terminal thioesterase domain was involved in the Claisen-type cyclization.
Sho Furumura, Taro Ozaki, Akihiro Sugawara, Yohei Morishita, Kento Tsukada, Tatsuya Ikuta, Asuka Inoue, Teigo Asai   +7 more
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Thermal study of chalcones [PDF]

Journal of Thermal Analysis and Calorimetry, 2018
Chalcones α-β-unsaturated ketones are found in large plant species. Synthesis of chalcones and its three analogues hydroxy group at 2′, 3′ and 4′ positions (2–4) was carried out. The studies of thermal behavior were made by thermogravimetry (TG) and differential scanning calorimetry, both under oxygen and nitrogen purge gases.
Marcelo Kobelnik, Leonardo Miziara Barboza Ferreira, Luis Octavio Regasini, Luiz Antonio Dutra, Vanderlan da Silva Bolzani, Clóvis Augusto Ribeiro   +5 more
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Study of Michael addition on chalcones and or chalcone analogues

Journal of Saudi Chemical Society, 2012
AbstractMichael addition reaction of 1,3-diphenyl-propenone 1a, e, and f with o-amino thiophenol in the presence of indium trichloride gave the benzothiazine derivatives 2a–c. Condensation of the compound 1a, e with o-phenylene diamine in triethylamine gave the benzodiazepine derivatives 3a–b.
Al-Jaber, Nabila A., Bougasim, Amal S.A., Karah, Makarem M.S.   +2 more
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chalcones [PDF]

, 2014
Citation: 'chalcones' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.C00966 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
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Phthalocyanine-chalcone conjugates

Journal of Porphyrins and Phthalocyanines, 2016
A phthalocyanine-chalcone conjugate was previously reported to retain the full photodynamic activity of the phthalocyanine and a slightly lowered antivascular effect of the chalcone. Assuming that it was due to an insufficient release of the chalcone, we described here several grafting modes applied to the preparation of phthalocyanine-chalcone ...
Aribi, Fallia, Vey, Charlene, Topkaya, Derya, Kostakoglu, Sinem Tuncel, Fournier-Dit-Chabert, Jérémie, Büyükekşi, Sebile Işik, Taşkin, Gökçe Canan, Alpugan, Serkan, Albrieux, Florian, Gürek, Ayşe Gül, Cucca, Mélissa, Bennis, Khalil, Atilla, Devrim, Ahsen, Vefa, Ducki, Sylvie, Dumoulin, Fabienne   +15 more
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Synthesis, Antioxidant and Antimicrobial Activities of a Novel Series of Chalcones, Pyrazolic Chalcones, and Allylic Chalcones

Pharmacology & Pharmacy, 2011
A new series of chalcones (4a-c) and allylicchalcones (11a-b) have been prepared by the Claisen-Schmidt condensation. A novel series of pyrazolicchalcones (5a-c) have been synthesized by the reaction of respective chalcones (4a-c) and hydrazine hydrate.
Tan Nhut Doan, Dao Thanh Tran
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Simple chalcones and bis-chalcones ethers as possible pleiotropic agents

Journal of Enzyme Inhibition and Medicinal Chemistry, 2015
The synthesis, the antioxidative properties and the lipoxygenase (LOX) and acetylcholinesterase (AChE) inhibition of a number of 4-hydroxy-chalcones diversely substituted as well as of a series of bis-chalcones ether derivatives are reported. The chalcones derivatives were readily produced using a Claisen-Schmidt condensation in a ultra sound bath in ...
Liargkova, T., Hadjipavlou-Litina, D.J., Koukoulitsa, C., Voulgari, E., Avgoustakis, C.   +4 more
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Chalcones X : Syntheses of Naphthalene Chalcone Analogues

, 1972
Department of Chemistry, H. B. Technological Institute, Kanpur Received 23 October 1971; revised MSS received 27 March 1972 Chalcones X : Syntheses of Naphthalene Chalcone Analogues.
SHYAM SUNDER MISRA, DINKAR
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