Results 21 to 30 of about 25,157 (251)
Journal of Taibah University for Science, 2021 Twelve novel chalcones were synthesized using 2-alkyloxy-naphthaldehydes and Mannich bases of 4-hydroxyacetophenone. The chalcones were characterized using FTIR, 1D and 2D NMR and HRMS spectroscopy.
Ghadah Aljohani +4 more
doaj +1 more source
Design and synthesis of new inhibitors of p53–MDM2 interaction with a chalcone scaffold [PDF]
, 2019 The virtual screening of a library of chalcone derivatives led us to the identification of potential new MDM2 ligands. The chalcones with the best docking scores obeying the Lipinski rule of five were subsequently prepared by base-catalyzed aldol ...
Cidade, Honorina +12 more
core +3 more sources
Advances in the Synthesis of Heteroaromatic Hybrid Chalcones
Molecules, 2023 Chalcones continue to occupy a venerated status as scaffolds for the construction of a variety of heterocyclic molecules with medicinal and industrial properties. Syntheses of hybrid chalcones featuring heteroaromatic components, especially those methods
Ajay Mallia, Joseph Sloop
doaj +1 more source
Angelica keiskei, an emerging medicinal herb with various bioactive constituents and biological activities. [PDF]
, 2017 Angelica keiskei (Miq.) Koidz. (Umbelliferae) has traditionally been used to treat dysuria, dyschezia, and dysgalactia as well as to restore vitality. Recently, the aerial parts of A. keiskei have been consumed as a health food.
Jafari, Mahtab +3 more
core +1 more source
The solubility and stability of heterocyclic chalcones compared with trans-chalcone [PDF]
Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials, 2020 Heterocyclic chalcones are a recently explored subgroup of chalcones that have sparked interest due to their significant antibacterial and antifungal capabilities. Herein, the structure and solubility of two such compounds, (E)-1-(1H-pyrrol-2-yl)-3-(thiophen-2-yl)prop-2-en-1-one and (E)-3-phenyl-1-(1H-pyrrol-2-yl)prop-2-en-1-one, are assessed.
Stephen G. Sweeting +8 more
openaire +4 more sources
Molecules, 2021 Over the past several decades, photopolymerization has become an active research field, and the ongoing efforts to develop new photoinitiating systems are supported by the different applications in which this polymerization technique is involved ...
Nicolas Giacoletto, Frédéric Dumur
doaj +1 more source
Microwave-Assisted Synthesis and Evaluation of Antimicrobial Activity of 3-{3-(s-Aryl and s-Heteroaromatic)acryloyl}-2Hchromen-2-one Derivatives [PDF]
, 2010 The exploration of potential utilization of microwaves as an energy source for heterocyclic synthesis was herein investigated using condensation of 3-acetylcoumarin (1) with aromatic and heteroaromatic aldehydes to afford the corresponding aromatic ...
Ajani +47 more
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Determination of the lipophilicity of 2'-hydroxychalcones by RP HPLC method [PDF]
Hemijska Industrija, 2016 Lipophilicity of twelve synthesized chalcones, whose ring B is a ortho, meta or para monosubstituted with alkyl, oxyalkyl groups or halogens was determined by reverse phase liquid chromatography, using octadecyl-functionalized (RP-18) silica gel
Bašić Jasmina V. +4 more
doaj +1 more source
Novel chalcone-based fluorescent human histamine H 3 receptor ligands as pharmacological tools [PDF]
, 2012 Novel fluorescent chalcone-based ligands at human histamine H(3) receptors (hH(3)R) have been designed, synthesized, and characterized. Compounds described are non-imidazole analogs of ciproxifan with a tetralone motif.
Tomasch, Miriam +3 more
core +1 more source
E-Journal of Chemistry, 2004 Eleven new chalcones have been sysnthesised by condensing 3-bromo-4-(p-tolyl sulphonamido) acetophenone with different aromatic aldehydes using the method or Rohrman et al. The antimicrobial activity of these chalcones has been tested by adopting “paper
Miss Rashmi Jain +2 more
doaj +1 more source