Results 21 to 30 of about 17,130 (245)
Identification and Functional Characterization of Fungal Chalcone Synthase and Chalcone Isomerase
By mining fungal genomic information, a noncanonical iterative type I PKS fused with an N-terminal adenylation-thiolation didomain, which catalyzes the formation of naringenin chalcone, was found. Structural prediction and molecular docking analysis indicated that a C-terminal thioesterase domain was involved in the Claisen-type cyclization.
Sho Furumura +7 more
openaire +2 more sources
Eleven new chalcones have been sysnthesised by condensing 3-bromo-4-(p-tolyl sulphonamido) acetophenone with different aromatic aldehydes using the method or Rohrman et al. The antimicrobial activity of these chalcones has been tested by adopting “paper
Miss Rashmi Jain +2 more
doaj +1 more source
Synthesis, spectral correlation and insect antifeedant activities of some 2-benzimidazole chalcones
Some substituted styryl 2-benzimidazole ketones have been synthesised by fly-ash:H2SO4 catalysed aldol condensation of 2-benzimidazole methyl ketone and various substituted benzaldehydes in microwave oven. The yields of these chalcones are more than 70%.
P. Janaki, K.G. Sekar, G. Thirunarayanan
doaj +1 more source
BIOLOGICAL ACTIVITIES AND NOVEL APPLICATIONS OF CHALCONES [PDF]
This review provides information on the biological activities of chalcones (whether natural or synthetic derivatives) on different organisms, as well as an overview of the functions and possible new applications of these plant secondary metabolites on ...
C. DÍAZ-TIELAS +3 more
doaj +2 more sources
Chalcones to control Alternaria alternata in murcott tangor fruits
Alternaria brown spot (ABS), caused by the fungus Alternaria alternata pathotype tangerine, is one of the main phytosanitary problems for mandarin growers.
Renato Barbosa Camargos +8 more
doaj +3 more sources
Cancer stem cells (CSCs) drive metastasis, relapse and resist conventional apoptosis‐inducing chemotherapies. We report a cobalt(III)‐cyclam complex with pyrene and diflunisal moieties that reduces the viability of breast CSCs at low micromolar concentrations.
Jiaxin Fang +7 more
wiley +2 more sources
Chalcones : Synthesis, structure diversity and pharmacological aspects [PDF]
The diverse pharmacological activities of chalcones, such as antioxidant, antimicrobial, anticancer, and antihepatotoxic, attract many researchers to isolate and elucidate them from nature and to develop efficient synthetic method.
Mustofa, .- +4 more
core +2 more sources
One catalyst for two products: CO acts as a molecular trigger for adaptive alkyne hydrogenation using supported Pd nanoparticles. The catalyst reversibly switches between the formation of alkanes under H2 and Z‐alkenes under H2/CO for 37 structurally diverse alkynes.
Manisha Durai +7 more
wiley +2 more sources
Several biological effects of chalcones have been reported to be associated with their thiol reactivity. In vivo, the reactions can result in the formation of small-molecule or protein thiol adducts.
Fatemeh Kenari +2 more
doaj +1 more source
Molecular docking and dynamics analysis of halogenated imidazole chalcone as anticancer compounds [PDF]
Cancer is one of the three biggest causes of death in the world. The development of new drugs against this disease is a serious study that must be carried out in order to reduce mortality and extend the life span of sufferers.
Winarto Haryadi, Harno Dwi Pranowo
doaj +3 more sources

