Results 11 to 20 of about 15,473 (263)

The solubility and stability of heterocyclic chalcones compared with trans-chalcone [PDF]

open access: yesActa Crystallographica Section B Structural Science, Crystal Engineering and Materials, 2020
Heterocyclic chalcones are a recently explored subgroup of chalcones that have sparked interest due to their significant antibacterial and antifungal capabilities. Herein, the structure and solubility of two such compounds, (E)-1-(1H-pyrrol-2-yl)-3-(thiophen-2-yl)prop-2-en-1-one and (E)-3-phenyl-1-(1H-pyrrol-2-yl)prop-2-en-1-one, are assessed.
Stephen G. Sweeting   +8 more
openaire   +4 more sources

Chalcone Scaffolds, Bioprecursors of Flavonoids: Chemistry, Bioactivities, and Pharmacokinetics

open access: yesMolecules, 2021
Chalcones are secondary metabolites belonging to the flavonoid (C6-C3-C6 system) family that are ubiquitous in edible and medicinal plants, and they are bioprecursors of plant flavonoids.
Mithun Rudrapal   +7 more
doaj   +1 more source

Structural, Vibrational and Electrochemical Analysis and Antibacterial Potential of Isomeric Chalcones Derived from Natural Acetophenone

open access: yesApplied Sciences, 2020
Background: Chalcones are part of a family of small phenolic compounds that are being extensively studied for presenting a diversity of molecular structures and biological activities. In this paper, two chalcones, (E)-1-(2-hydroxy-3,4,6-trimethoxyphenyl)-
Priscila Teixeira da Silva   +15 more
doaj   +1 more source

Chalcones: Synthetic Chemistry Follows Where Nature Leads [PDF]

open access: yes, 2021
Chalcones belong to the flavonoid class of phenolic compounds. They form one of the largest groups of bioactive natural products. The potential anticancer, anti-inflammatory, antimicrobial, antioxidant, and antiparasitic properties of naturally occurring
Jasim, MA   +5 more
core   +2 more sources

Natural Chalcones and Derivatives in Colon Cancer: Pre-Clinical Challenges and the Promise of Chalcone-Based Nanoparticles

open access: yesPharmaceutics, 2023
Colon cancer poses a complex and substantial global health challenge, necessitating innovative therapeutic approaches. Chalcones, a versatile class of compounds with diverse pharmacological properties, have emerged as promising candidates for addressing ...
Soufyane Hba   +9 more
doaj   +1 more source

Synthesis, molecular docking and biochemical analysis of aminoalkylated naphthalene-based chalcones as acetylcholinesterase inhibitors

open access: yesJournal of Taibah University for Science, 2021
Twelve novel chalcones were synthesized using 2-alkyloxy-naphthaldehydes and Mannich bases of 4-hydroxyacetophenone. The chalcones were characterized using FTIR, 1D and 2D NMR and HRMS spectroscopy.
Ghadah Aljohani   +4 more
doaj   +1 more source

Identification and Functional Characterization of Fungal Chalcone Synthase and Chalcone Isomerase

open access: yesJournal of Natural Products, 2023
By mining fungal genomic information, a noncanonical iterative type I PKS fused with an N-terminal adenylation-thiolation didomain, which catalyzes the formation of naringenin chalcone, was found. Structural prediction and molecular docking analysis indicated that a C-terminal thioesterase domain was involved in the Claisen-type cyclization.
Sho Furumura   +7 more
openaire   +2 more sources

Advances in the Synthesis of Heteroaromatic Hybrid Chalcones

open access: yesMolecules, 2023
Chalcones continue to occupy a venerated status as scaffolds for the construction of a variety of heterocyclic molecules with medicinal and industrial properties. Syntheses of hybrid chalcones featuring heteroaromatic components, especially those methods
Ajay Mallia, Joseph Sloop
doaj   +1 more source

Recent Advances in bis-Chalcone-Based Photoinitiators of Polymerization: From Mechanistic Investigations to Applications

open access: yesMolecules, 2021
Over the past several decades, photopolymerization has become an active research field, and the ongoing efforts to develop new photoinitiating systems are supported by the different applications in which this polymerization technique is involved ...
Nicolas Giacoletto, Frédéric Dumur
doaj   +1 more source

Synergy between Experimental and Theoretical Investigations Reveals the Anti‑Corrosion Efficiency of Imine-Chalcones

open access: yes, 2021
The inhibitory action of three imine-chalcones on carbon steel corrosion in HCl was investigated by theoretical and experimental methods. Quantum descriptors were calculated at the conductor-like polarizable continuum model (CPCM)-Becke-3 Parameter-Lee ...
Marcelo A. Neves (6047651)   +5 more
core   +1 more source

Home - About - Disclaimer - Privacy