Results 31 to 40 of about 17,130 (245)

Green Synthesis, Characterization, Photophysical and Electrochemical Properties of Bis-chalcones

open access: yesInternational Journal of Electrochemical Science, 2014
Donor-acceptor conjugated dienes (bis-chalcones) were synthesized via an ultrasonic radiation, accomplished by the reaction between 3-acetyl-2,5-dimethylthiophene/1 (2,5-dimethyl-furan-3-yl)- ethanone and terephthalaldehyde.
Abdullah M. Asiri   +5 more
doaj   +1 more source

A Comprehensive Review of Aminochalcones

open access: yesMolecules, 2020
Chalcones, members of the flavonoid family, display a plethora of interesting biological activities including but not limited to antioxidant, anticancer, antimicrobial, anti-inflammatory, and antiprotozoal activities.
Rimsha Irfan   +3 more
doaj   +1 more source

Synthesis and Pharmacological Evaluation of Some Phenylpyrazolo Indoquinoxaline Derivatives

open access: yesE-Journal of Chemistry, 2011
Indoloquinoxalin was fused with 2,3 diphenyl quinoxaline by a methylene bridge which was then allowed for acetylation. The acetylated product was made to react with different aromatic aldehydes to give chalcones.
CH. Sridevi, K. Balaji, A. Naidu
doaj   +1 more source

Pharmacological Properties of Chalcones: A Review of Preclinical Including Molecular Mechanisms and Clinical Evidence

open access: yesFrontiers in Pharmacology, 2021
Chalcones are among the leading bioactive flavonoids with a therapeutic potential implicated to an array of bioactivities investigated by a series of preclinical and clinical studies.
Bahare Salehi   +22 more
doaj   +1 more source

Pharmacological potential of natural chalcones: a recent studies and future perspective

open access: yesFrontiers in Pharmacology
Chalcones isolated from natural sources are the primary metabolites of numerous biologically intriguing and pharmacologically essential drugs. Chalcones’ pharmacological properties are believed to result from a double bond conjugated to carbonyl ...
Suman Adhikari   +6 more
doaj   +1 more source

Mechanochemical synthesis of indolyl chalcones with antiproliferative activity

open access: yesGreen Chemistry Letters and Reviews, 2022
An efficient eco-friendly one-step mechanochemical synthesis of indole hybrid chalcones via the Claisen–Schmidt condensation of 1-methylindole-3-carboxaldehyde with various substituted acetophenones is described using liquid assisted grinding in a high ...
Zuzana Kudličková   +4 more
doaj   +1 more source

Beta-Amino Phosphine Mn Catalysts for 1,4-Transfer Hydrogenation of Chalcones and Allylic Alcohol Isomerization [PDF]

open access: yes, 2019
Beta-amino phosphines derived from amino-acids are excellent supporting ligands for Mn(I) transfer hydrogenation catalysts. Namely, a variety of ketones and chalcones are efficiently reduced under mild conditions (2-propanol, 3 h, 60 °C).
David, Lacy   +3 more
core   +1 more source

Antiproliferative activity and p53 upregulation effects of chalcones on human breast cancer cells

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2019
Chalcones are valuable structures for drug discovery due to their broad bioactivity spectrum. In this study, we evaluated 20 synthetic chalcones against estrogen-receptor-positive breast cancer cells (MCF-7 line) and triple-negative breast cancer (TNBC ...
Mariana Bastos dos Santos   +10 more
doaj   +1 more source

Study of Michael addition on chalcones and or chalcone analogues

open access: yesJournal of Saudi Chemical Society, 2012
AbstractMichael addition reaction of 1,3-diphenyl-propenone 1a, e, and f with o-amino thiophenol in the presence of indium trichloride gave the benzothiazine derivatives 2a–c. Condensation of the compound 1a, e with o-phenylene diamine in triethylamine gave the benzodiazepine derivatives 3a–b.
Al-Jaber, Nabila A.   +2 more
openaire   +1 more source

Phthalocyanine-chalcone conjugates

open access: yesJournal of Porphyrins and Phthalocyanines, 2016
A phthalocyanine-chalcone conjugate was previously reported to retain the full photodynamic activity of the phthalocyanine and a slightly lowered antivascular effect of the chalcone. Assuming that it was due to an insufficient release of the chalcone, we described here several grafting modes applied to the preparation of phthalocyanine-chalcone ...
Aribi, Fallia   +15 more
openaire   +3 more sources

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