The genes and enzymes of phosphonate metabolism by bacteria, and their distribution in the marine environment [PDF]
Phosphonates are compounds that contain the chemically-stable carbon-phosphorus (C-P) bond. They are widely distributed amongst more primitive life forms including many marine invertebrates and constitute a significant component of the Dissolved Organic
Juan F Villarreal-Chiu +2 more
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Molecular basis for azetidine-2-carboxylic acid biosynthesis [PDF]
Azetidine-2-carboxylic acid (AZE) is a long-known plant metabolite. Recently, AZE synthases have been identified in bacterial natural product pathways involving non-ribosomal peptide synthetases.
Tim J. Klaubert +8 more
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The Effect of Chalcone Isomerase Gene Silencing on Pigment Production Pathway in Petunia hybrida with RNAi Technology [PDF]
Introduction Flower color is one of the most significant characteristics in ornamental plant breeding. New varieties of various plants in relation to their flower color have been obtained by monitoring the expression levels of genes involved or ...
F. Keykha Akhar +3 more
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Intramolecular Benzoin Reaction Catalyzed by Benzaldehyde Lyase from Pseudomonas Fluorescens Biovar I [PDF]
AbstractIntramolecular benzoin reactions catalyzed by benzaldehyde lyase from Pseudomonas fluorescens biovar I (BAL) are reported. The structure of the substrates envisaged for this reaction consists of two benzaldehyde derivatives linked by an alkyl chain.
Karel Hernández +7 more
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Bacterial Conversion of Hydroxylamino Aromatic Compounds by both Lyase and Mutase Enzymes Involves Intramolecular Transfer of Hydroxyl Groups [PDF]
ABSTRACT Hydroxylamino aromatic compounds are converted to either the corresponding aminophenols or protocatechuate during the bacterial degradation of nitroaromatic compounds. The origin of the hydroxyl group of the products could be the substrate itself (intramolecular transfer mechanism) or the solvent water (intermolecular ...
Lloyd J, Nadeau +2 more
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Discovery of unique lanthionine synthetases reveals new mechanistic and evolutionary insights.
Lantibiotic synthetases are remarkable biocatalysts generating conformationally constrained peptides with a variety of biological activities by repeatedly utilizing two simple posttranslational modification reactions: dehydration of Ser/Thr residues and ...
Yuki Goto +5 more
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Developing unnatural functions and optimizing catalytic properties of enzymes are challenging tasks that require extensive engineering and screening of biocatalysts. In this study, we report the first example of enantiocomplementary intramolecular crossed aldehyde-ketone benzoin cyclizations catalyzed by benzaldehyde lyase.
Ling Yu, Zhijun Song
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Benzaldehyde Lyase-catalyzed intramolecular benzoin reactions
Póster presentado en BIOTRANS 2015, celebrado del 26 al 30 de julio de 2015 en Viena (Austria) Intramolecular stereoselective carboligations are important reactions in organic synthetic chemistry essential for the access of natural occurring compounds and analogues.
Hernández Sánchez, Karel +7 more
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The Pyridoxal-5'-Phosphate-Dependent Enzymes of <i>Mycobacterium tuberculosis</i>. [PDF]
Peracchi A, Baker B.
europepmc +1 more source
Improvement of Catalytic Activity and Thermostability of Alginate Lyase VxAly7B-CM via Rational Computational Design Strategies. [PDF]
Ma X +7 more
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