Results 21 to 30 of about 1,068 (106)
The Bahamian octocoral Pseudopterogorgia elisabethae is the source of pseudopterosins, diterpene glycosides with potent anti-inflammatory activity.
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This work describes the design, the synthesis and the biological studies of saccharadic inhibitors of two bacterial phosphoenolpyruvate lyases, KDO8PS and DAH7PS. Their structures are based on an extensive study of recent biochemical and biological data.
Barthes, Nicolas
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MccB‐catalyzed C‐terminal Thioesterification for Protein Bioconjugation
Abstract Protein bioconjugation enables the installation of functional groups, probes, and payloads that cannot be genetically encoded, thereby enabling the study and manipulation of biological systems. An important class of intermediates in protein bioconjugation is C‐terminal protein α‐thioesters, which are kinetically stable yet thermodynamically ...
Di Yang, Amy M. Weeks
wiley +1 more source
Chitosan–Alginate Polyelectrolyte Systems: From Classical Release Models to the D‐PARMO Framework
Classical empirical models fail to predict the dynamic in vivo behavior of chitosan‐alginate nanocarriers. Bridging this translational gap, the novel D‐PARMO framework replaces purely descriptive curve‐fitting with a mechanistically informed operational model.
Parastoo Rekab, Akeem Adeyemi Oladipo
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Liver Fibrosis: Molecular Pathogenesis and Therapeutic Interventions
We systematically summarized the etiologies, diagnostic approaches, and pathogenic mechanisms of liver fibrosis. Also, the therapeutic interventions for liver fibrosis were systematically classified into two main categories: etiological treatment and mechanism‐based antifibrotic therapies.
Jiaorong Qu +8 more
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Chorismat ist ein wichtiger Verzweigungspunkt zwischen Primär- und Sekundärmetabolismus in Bakterien, Pflanzen und Pilzen. Verschiedene Chorismat-umsetzende Enzyme katalysieren die Bildung wichtiger, häufig chiraler oder aromatischer Moleküle, die häufig
Hubrich, Florian
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ABSTRACT Alternative DNA structure‐forming (i.e., non‐B) sequences such as H‐DNA‐forming sequences are enriched at chromosomal translocation hotspots in human cancer genomes, underscoring their role in genomic instability. H‐DNA is particularly susceptible to DNA damage by reactive oxygen species (ROS), a common byproduct from both endogenous ...
Alex W. Klattenhoff +4 more
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Harnessing Free Radical Scavenging Potential of Caffeic Acid as a Nutraceutical—A Review
Caffeic acid has emerged as a promising bioactive molecule with multiple pharmacological properties, including antioxidant, antimicrobial, anti‐inflammatory, organ protective properties and metal‐chelating ability. This review emphasizes the dietary sources, structural characteristic, molecular mechanism underlying health promoting effects of caffeic ...
Pavitra Behra +2 more
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The lacking essential amino acids, low digestibility, bioavailability, bitterness, and presence of anti‐nutritional factors that limit the consumption of plant proteins and their use in food formulations are discussed comprehensively. The findings of recent studies on novel technologies and computer‐based applications used to cope with these challenges
Humeyra Cavdar Dincturk +3 more
wiley +1 more source
A Holistic Characterization of Soy Protein Isolates From Different Breeding Lines
A roadmap illustrating how variability among soybean genotypes translates into structural and compositional differences that govern functionality, off‐flavor development, and protein quality. ABSTRACT Soy protein remains the leading plant protein in the growing alternative protein market.
Samira Feyzi, Baraem P. Ismail
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