Results 31 to 40 of about 1,068 (106)

A Chemiluminescence‐Activated Photodynamic Platform to Penetrate MRSA Biofilms and Counteract H2S‐Mediated Defense

Small Science, Volume 6, Issue 3, March 2026.
A chemiluminescence‐activated photodynamic system is developed to eradicate methicillin‐resistant Staphylococcus aureus (MRSA) biofilms without external light or antibiotics. CO2 generated in situ disrupts biofilms and propels nanocarriers for deep penetration, while hypericin generates reactive oxygen species and suppresses H2S‐mediated defenses. This
WeiYe Ren, WeiYi Cheng, Li He, JingQuan Chen, Liting He, Haorong Li, Guoying Zhou, Yinghui Wei, Ji‐Gang Piao, Dandan Bao   +9 more
wiley   +1 more source

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, Volume 13, Issue 11, 23 February 2026.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

Transient Cyclic Structured Oligonucleotide Designs for Therapeutic Applications

Current Protocols, Volume 6, Issue 2, February 2026.
Abstract Oligonucleotide‐based therapeutics are now widely used in clinical settings. From the late 1980s to the mid‐1990s, efforts to improve therapeutic efficacy focused on imparting drug‐like properties to oligonucleotides, emphasizing nuclease stability and target sequence affinity.
Sudhir Agrawal
wiley   +1 more source

Benzaldehyde Lyase-catalyzed intramolecular benzoin reactions

, 2015
Intramolecular stereoselective carboligations are important reactions in organic synthetic chemistry essential for the access of natural occurring compounds and analogues. Besides the chemical methodologies, a plethora of intramolecular C-C bond forming reactions exists in different metabolic pathways of living organism catalyzed by highly evolved ...
Hernández Sánchez, Karel, Petrillo, Giovanna, Usón, Isabel, Wandtke, Claudia M., Joglar Tamargo, Jesús, Parella, Teodor, Clapés Saborit, Pere, Bujons, Jordi   +7 more
openaire   +1 more source

The Acetyl‐CoA‐NLRX1 Axis Acts as a Key Player in Mitophagy and Drug Resistance

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ping Jin, Biao Hu, Jingwen Jiang, Li Xu
wiley   +1 more source

Untangling the Reaction Mechanism of the Polysaccharide Lyase PL42 Using QM/MM Metadynamics Simulations. [PDF]

J Chem Inf Model
Alonso-Gil S, Kondo T, Fushinobu S, Sánchez-Murcia PA.   +3 more
europepmc   +1 more source

Pyridoxal 5'-Phosphate-Dependent Enzymatic Decarboxylative Annulation. [PDF]

J Am Chem Soc
Chai W, Luo S, Xi W, He X, Zhang T, Zou Y, Hai Y.   +6 more
europepmc   +1 more source

The Pyridoxal-5'-Phosphate-Dependent Enzymes of <i>Mycobacterium tuberculosis</i>. [PDF]

ACS Infect Dis
Peracchi A, Baker B.
europepmc   +1 more source

Improvement of Catalytic Activity and Thermostability of Alginate Lyase VxAly7B-CM via Rational Computational Design Strategies. [PDF]

Mar Drugs
Ma X, Zhu K, Wang K, Liao W, Yang X, Yu W, Wang W, Han F.   +7 more
europepmc   +1 more source

Phosphoproteome-derived peptide libraries for deep specificity profiling of phosphatases and phospholyases. [PDF]

Proc Natl Acad Sci U S A
Radziwon K, Campbell LA, Mazurkiewicz LE, Jalalishvili S, Eppinger I, Parikh A, Weeks AM.   +6 more
europepmc   +1 more source