Diazo Transfer From Nitrous Oxide Employing Phosphorus Ylides
Angewandte Chemie, EarlyView.A phosphorus ylide‐mediated strategy achieves the direct fixation of nitrous oxide (N2O) to access diazo compounds, which after intra‐ or intermolecular trapping, afford N2‐containing organic building blocks. This approach provides an alternative to hazardous diazo‐transfer reagents and establishes N2O fixation as a sustainable methodology.
Jhen‐Kuei Yu +4 more
wiley +2 more sources
Chemical and Pharmaceutical Bulletin, 2013 A new class of mono and bis heterocycles-styrylsulfonylmethyl 1,3,4-oxadiazoles, pyrazolyl/isoxazolyl-1,3,4-oxadiazoles were prepared and studied their antioxidant activity. The compound methyl substituted 2-(p-methylphenylamino-sulfonylmethyl)-5-[Z-(p-methylstyrylsulfonylmethyl)]-1,3,4-oxadiazole displayed slightly higher antioxidant activity than the
Guda, Mallikarjuna Reddy +5 more
openaire +3 more sources
A convenient synthesis of 1,3,4-thiadiazole and 1,3,4-oxadiazole based peptidomimetics employing diacylhydrazines derived from amino acids [PDF]
, 2010 Synthesis of novel orthogonally protected 1,3,4-thiadiazole and 1,3,4-oxadiazole tethered dipeptide mimetics is described. Both the heterocycles are prepared via a set of diacylhydrazines derived from amino acids.
Lamani, R.S. +3 more
core +1 more source
Synthesis of 1,3,4-Oxadiazole Derivatives from Ethyl-2-Piperidone-3-Carboxylate [PDF]
مجلة التربية والعلم, 2012 In the present work, some new 1,3,4- Oxadiazole derivatives have been synthesized from Ethyl-2-Piperidone-3-Carboxylate. The reaction of the ethyl ester with hydrazine hydrate afforded the corresponding hydrazide (I).
M. A. Sheat, O. I. Mohammed
doaj +1 more source
Synthesis of Azoles Condensed with, or Linked to, Nitroxides [PDF]
, 2015 Nitroxides connected to indoles, tetrazoles, or 1,3,4-oxadiazoles were synthesized by conventional and microwave-assisted cyclization reactions. New approaches to pyrrole-, pyrazole-, and triazoleannulated nitroxides are described.
Bognár, Balázs +4 more
core +1 more source
Synthesis, Characterization and Biological Investigation of Some New Hydroxy – 1,3,4 – Oxadiazole Derivatives [PDF]
Kirkuk Journal of Science, 2016 study the solid compounds of hydroxy 1,3,4 – oxadiazoles have been synthesized by reaction of acid hydrazides with CS2 in the presence of KOH.
Afraa S. S, Jawdat H. A
doaj +1 more source
Crystal structure of 5-(adamantan-1-yl)-3-= (4-chloroanilino)methyl-2,3-dihydro-1,3,4-oxadiazole-2-thione, C19H22ClN3OS [PDF]
, 2016 C19H22ClN3OS, orthorhombic, P212121 (no. 19), a = 7.0418(2) Å, b = 10.8802(3) Å, c = 23.5506(6) Å, V = 1804.36(8) Å3, Z = 4, R gt (F) = 0.0413, wR ref (F 2
Al-Alshaikh, M. A. +5 more
core +1 more source
SYNTHESIS OF MONO-SUBSTITUTED AND SIMMETRICALLY 2, 5-DISUBSTITUTED 1, 3, 4-OXADIAZOLES [PDF]
Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2012 In recent years 1,3,4-oxadiazoles have received considerable attention due to their wide range of biological activities and practical importance. They form an important class of fi ve-member heterocyclic compounds with a variety of derivatives.
Z. Ribcovskaia, F. Macaev
doaj
1,2,4- and 1,3,4-Oxadiazoles as Scaffolds in the Development of Antiparasitic Agents
, 2017 In this review, we present the potential use of the heterocyclic oxadiazole rings in the design and synthesis of new drugs to treat parasitic infections.
Paulo Pitasse-Santos +2 more
semanticscholar +1 more source
Journal of Medicinal Chemistry, 2016 Herein, we report the discovery and structure-activity relationships of 5-substituted-2-[(3,5-dinitrobenzyl)sulfanyl]-1,3,4-oxadiazoles and 1,3,4-thiadiazoles as a new class of antituberculosis agents.
Galina Karabanovich +18 more
semanticscholar +1 more source