Results 151 to 160 of about 9,299,574 (208)

Comparative Hydrophobicity, Solubility, and Metabolic Stability of 4(1<i>H</i>)-Pyridones, 4(1<i>H</i>)-Quinolones, and 9(10<i>H</i>)-Acridones. [PDF]

ACS Med Chem Lett
Ren R, Zhong L, Noack C, Kaushik D, Leas DA, Wang X, Dong Y, Charman SA, Vennerstrom JL.   +8 more
europepmc   +1 more source

Iminopyridonato Iridium Complexes: <i>O</i>-Functionalization via C-X Bond Cleavage. [PDF]

Inorg Chem
Moždiak O, Tydlitát J, Růžičková Z, Steffen A, Jambor R.   +4 more
europepmc   +1 more source

Novel Antifungal Pyridine Alkaloids from Endophytic Fungus <i>Penicillium citrinum</i> VDL118. [PDF]

J Fungi (Basel)
Yang M, Hu S, Zhang ZY, Yang FZ, Yang XQ, Xie SD, Zhang YJ, Zhao P, Zhu GL.   +8 more
europepmc   +1 more source

Dipole moment studies of some derivatives of 4-pyridone

Australian Journal of Chemistry, 1972
The dipole moments of 13 derivatives of 4-pyridone were measured. Attempts to obtain a value for 4-pyridone were unsuccessful but a value of 6.O D is compatible with other evidence. Dipole moment and n.m.r, evidence indicated that for N-phenyl-4-pyridone the phenyl group is inductively electron-repelling (in contrast to that reported)1,2 for N ...
BD Batts, AJ Madeley
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Synthesis of 2,3-Dihydro-4-pyridones and 4-Pyridones by the Cyclization Reaction of Ester-Tethered Enaminones

The Journal of Organic Chemistry, 2020
2,3-Dihydro-4-pyridone skeleton is an important building block in organic synthesis because it features several reaction sites with nucleophilic or electrophilic properties. Herein, we disclose a method for its formation by intramolecular cyclization of ester-tethered enaminones, which can easily be synthesized from readily available materials, such as
Milovan Stojanović, Slobodan Bugarski, Marija Baranac-Stojanović   +2 more
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Synthesis, solvatochromic properties and antimicrobial activities of some novel pyridone-based disperse disazo dyes

Journal of Molecular Liquids, 2013
In this study, 5-amino-4-arylazo-3-methyl-1H-pyrazoles (2a-l) were diazotized and coupled with 3-cyano-6-hydroxy-4-methyl-2-pyridone to give pyridone-based disperse disazo dyes (3a-l). The newly synthesized twelve pyridone-based disperse disazo dyes were
Aykut Demirçali, Mustafa Yamaç
exaly   +2 more sources

Synthesis of Multifunctionalized 2,3-Dihydro-4-pyridones and 4-Pyridones via the Reaction of Carbamoylated Enaminones with Aldehydes

The Journal of Organic Chemistry, 2018
The novel and effective diastereoselective synthesis of multifunctionalized dihydropyridones, including CF3-substituted derivatives, has been developed on the basis of the piperidine-promoted domino reaction of carbamoylated enaminones with aldehydes.
Dmitrii L. Obydennov, Asmaa I. El-Tantawy, Vyacheslav Y. Sosnovskikh   +2 more
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Synthesis and antitumour activity of 4-hydroxy-2-pyridone derivatives

European Journal of Medicinal Chemistry, 2000
4-hydroxy-2-pyridone derivatives 2 were prepared by reaction of 3-amino-3-dialkylaminopropenoates with bis(2,4,6-trichlorophenyl)malonate. These compounds were further reacted with a set of aldehydes to give bis(pyridyl)methanes 3 and 4.
Cenzo Congiu, Valentina Onnis
exaly   +2 more sources

Preparation and antiinflammatory activity of 2- and 4-pyridones

Journal of Medicinal Chemistry, 1982
Several N-alkyl- and N-arylacetoacetamides have been self-condensed to form pyridones. N-Alkylacetoacetamides give 2-pyridones, while N-arylacetoacetamides give 4-pyridones. In an attempt to develop nonacidic, nonsteroidal antiinflammatory agents, the pyridones were tested in a carrageenan-induced pedal edema assay in rats.
J B, Pierce, Z S, Ariyan, G S, Ovenden
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ChemInform Abstract: ACYLATION OF 4‐PYRIDONE

Chemischer Informationsdienst, 1980
AbstractBei der Acylierung von 4‐Pyridon (I) mit aliphatischen Carbonsäure‐anhydriden und ‐chloriden oder freien Säuren in Gegenwart von Dicyclohexylcarbodiimid erhält man ausschließlich die N‐Acyl‐4‐pyridone (III).
F. EFFENBERGER, A. O. + MUECK, E. BESSEY
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