Microwave assisted synthesis of 2-pyridone and 2-pyridone based compounds [PDF]
Hemijska Industrija, 2014 2-Pyridones are important heterocyclic compounds that are widely used in medical chemistry, and their various derivatives have significant biological and medical applications.
Mijin Dušan Ž. +3 more
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2-Pyridone: monoclinic polymorph [PDF]
Acta Crystallographica Section E, 2009 The asymmetric unit in the title compound, C5H5NO, comprises two independent but virtually identical molecules of 2-pyridone, and represents a monoclinic polymorph of the previously reported orthorhombic (P212121) form [Penfold (1953). Acta Cryst. 6, 591&
Edward R. T. Tiekink +2 more
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Palladium-Catalyzed β-C(sp3)–H Bond Arylation of Tertiary Aldehydes Facilitated by 2-Pyridone Ligands [PDF]
Molecules2-Pyridone ligand-facilitated palladium-catalyzed direct C–H bond functionalization via the transient directing group strategy has become an attractive topic.
Ziting Xu +4 more
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2-Pyridone natural products as inhibitors of SARS-CoV-2 main protease [PDF]
Chemico-Biological Interactions, 2021 The disease, COVID-19, is caused by the severe acute respiratory coronavirus 2 (SARS-CoV-2) for which there is currently no treatment. The SARS-CoV-2 main protease (Mpro) is an important enzyme for viral replication.
Ian R Pottie
exaly +3 more sources
Acta Crystallographica Section E, 2011 The crystal structure of the title compound, C6H7NO, is stabilized by intermolecular N—H...O hydrogen bonds, resulting in inversion dimers. The structure is further consolidated by weak C—H...O hydrogen bonds.
Shulin Mao, Luo Yanghui, Pan Meiling
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Diversity-oriented functionalization of 2-pyridones and uracils [PDF]
Nature Communications, 2021 Diversity-oriented synthesis of 2-pyridone and uracil derivatives is in urgent need in medicinal chemistry as they are useful pharmacophores. Here the authors show that palladium/norbornene cooperative catalysis enabled dual-functionalization of ...
Yong Shang +8 more
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Bis(μ-1,4-dihydropyridin-4-one-κ2O:O)di-μ-perchlorato-κ4O:O′-bis[aqua(1,4-dihydropyridin-4-one-κO)copper(II)] tetraaquabis(1,4-dihydropyridin-4-one-κO)copper(II) tetrakis(perchlorate) 1,4-dihydropyridin-4-one disolvate [PDF]
IUCrDataThe reaction of copper(II) perchlorate hexahydrate with 4-pyridone and pyrazine in 1-propanol serendipitously yielded crystals of the solvated title double salt, [Cu(C5H5NO)2(H2O)4][Cu2(ClO4)2(C5H5NO)4(H2O)2](ClO4)4·2C5H5NO, as a biproduct.
Mark M. Turnbull +2 more
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New thiazole, thiophene and 2-pyridone compounds incorporating dimethylaniline moiety: synthesis, cytotoxicity, ADME and molecular docking studies [PDF]
BMC ChemistryVarious sets of thiazole, thiophene, and 2-pyridone ring structures containing a dimethylaniline component were synthesized. Substituted thiazoles 2–3 and thiophenes 5–7 were produced by reacting thiocarbamoyl compound 4 with α-halogenated reagents in ...
Heba M. Metwally +3 more
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Pyridone alkaloids from an Antarctic endolichenic Tolypocladium sp. [PDF]
Natural Products and BioprospectingThree new pyridone alkaloids, tolypyrone A (1), tolypyrosides A (2) and B (3), and a new tetramic acid 2′-epitolypoalbin (4), along with ten known compounds, were obtained from Tolypocladium sp.
Shasha Li +7 more
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Synthesis and characterization of Cu and Fe (1:2) metal complexes based on their substituted pyridones acid dyes and their application on wool fabrics [PDF]
Journal of Chemistry Letters, 2022 In this study, the investigation deals with synthesis of acid dyes from 4-amino-1-(4-sulfophenyl)- 3-methyl-5-pyrazolone and their pyridone derivatives and their metal complexes (Cu (II)and Fe (II)).
Olamide Ajani +2 more
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