Results 21 to 30 of about 4,834 (175)

SYNTHESIS AND ANTIHYPERLIPIDEMIC ACTIVITY OF CERTAIN NICOTINIC ACID DERIVATIVES [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 2005
3-Ethoxycarbonyl-4,6-dimethyl-2(1H)-pyridone I was prepared and converted to the corresponding sodium salt II. The latter reacted with certain chloroacetanilides to afford the corresponding ethers III.
Mohamed Abdel-Wahab, Abdel Ghany El-Helby   +1 more
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Ribonucleotide reductase, a novel drug target for gonorrhea

eLife, 2022
Antibiotic-resistant Neisseria gonorrhoeae (Ng) are an emerging public health threat due to increasing numbers of multidrug resistant (MDR) organisms. We identified two novel orally active inhibitors, PTC-847 and PTC-672, that exhibit a narrow spectrum ...
Jana Narasimhan, Suzanne Letinski, Stephen P Jung, Aleksey Gerasyuto, Jiashi Wang, Michael Arnold, Guangming Chen, Jean Hedrick, Melissa Dumble, Kanchana Ravichandran, Talya Levitz, Chang Cui, Catherine L Drennan, JoAnne Stubbe, Gary Karp, Arthur Branstrom   +15 more
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catena-Poly[[[(2-pyridone-κO)silver(I)]-μ-2-pyridone-κ2O:O] hexafluoridophosphate]

Acta Crystallographica Section E, 2010
The asymmetric unit of the polymeric title salt, {[Ag(C5H5NO)2]PF6}n, comprises an AgI cation (located on a twofold axis), two 2-pyridone ligands (with distinct coordination modes), and half a PF6− anion (situated on a centre of inversion). The
Edward R. T. Tiekink, Tyler Miller, Hadi D. Arman   +2 more
doaj   +1 more source

Inductive Production of the Iron-Chelating 2-Pyridones Benefits the Producing Fungus To Compete for Diverse Niches

mBio, 2021
Diverse 2-pyridone alkaloids have been identified with an array of biological and pharmaceutical activities, including the development of drugs. However, the biosynthetic regulation and chemical ecology of 2-pyridones remain largely elusive.
Bo Chen, Yanlei Sun, Shiqin Li, Ying Yin, Chengshu Wang   +4 more
doaj   +1 more source

Synthesis of New Aza-Heterocyclic Based on 2-Pyridone

Chemistry Proceedings
In this work, we present new methods of synthesis of different molecules including a 2-pyridone nucleus. First, we prepared a series of 1H-free 2-pyridones and N-alkyl 2-pyridones from ethyl cyanoacetate, aromatic aldehydes, various acetophenone ...
Ikram Baba-Ahmed, Zahira Kibou, Julio A. Seijas, Noureddine Choukchou-Braham, M. Pilar Vázquez-Tato   +4 more
doaj   +1 more source

Supramolecular Potential of Vanadium β-Diketonate and Picolinate Compounds and The First One-dimensional Oxidovanadium(IV) Complex with β-Diketonate Ligand

Acta Chimica Slovenica, 2014
Three vanadium compounds with β-diketonato or picolinato ligands were prepared and structurally characterized. In compounds [VO(tfpb)2]∞ (1) (tfpb = 4,4,4-trifluoro-1-phenylbutane-1,3-dionate) and [VO(acac)2(2-pyridone)] (2) the coordination of vanadium ...
Tanja Koleša Dobravc, Anton Meden, Franc Perdih   +2 more
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Enzymatic synthesis of vitamin B6 precursor [PDF]

Journal of the Serbian Chemical Society, 2013
3-Cyano-4-ethoxymethyl-6-methyl-2-pyridone is an important precursor in the synthesis of vitamin B6, obtained in the addition reaction between 2-cyanoacetamide and 1-ethoxy-2,4-pentanedione catalyzed by lipase from Candida rugosa ...
Prlainović Nevena Ž., Bezbradica Dejan I., Knežević-Jugović Zorica D., Veličković Dušan V., Mijin Dušan Ž.   +4 more
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Synthesis, structure and solvatochromic properties of 3-cyano-4,6-diphenyl-5-(3- and 4-substituted phenylazo)-2-pyridones [PDF]

Journal of the Serbian Chemical Society, 2010
A series of some new pyridone arylazo dyes was synthesized from the corresponding diazonium salts and 3-cyano-4,6-diphenyl-2-pyridone using the classical reaction for the synthesis of the azo compounds.
NINA TODOROVIĆ, GORDANA S. UŠĆUMLIĆ, NATAŠA V. VALENTIĆ, DUŠAN Ž. MIJIN, ALEKSANDAR D. MARINKOVIĆ, ADEL S. ALIMMARI   +5 more
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rac-2-Methyl-3,4,5,6-tetrahydro-2H-2,6-methano-1,3-benzoxazocin-4-one

Acta Crystallographica Section E, 2010
The title compound, C12H13NO2, represents a conformationally restricted 2-pyridone analogue of 1,4-dihydropyridine-type calcium antagonists and was selected for a crystal structure determination in order to explore some aspects of drug-receptor ...
Viktor Kettmann, Jan Světlík, Lucia Veizerová   +2 more
doaj   +1 more source

Gas-phase Lifetimes of Nucleobase Analogues by Picosecond Pumpionization and Streak Techniques

CHIMIA, 2014
The picosecond (ps) timescale is relevant for the investigation of many molecular dynamical processes such as fluorescence, nonradiative relaxation, intramolecular vibrational relaxation, molecular rotation and intermolecular energy transfer, to
Susan Blaser, Hans-Martin Frey, Cornelia G. Heid, Samuel Leutwyler   +3 more
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