Results 11 to 20 of about 4,834 (175)

Solid-Phase Synthesis of Diverse Macrocycles by Regiospecific 2‑Pyridone Formation: Scope and Applications [PDF]

JACS Au
Skander A. Abboud, Thomas Kodadek
doaj   +2 more sources

Recent advances in chemistry and pharmacological aspects of 2-pyridone scaffolds

Journal of Saudi Chemical Society, 2021
Background: The chemistry and applications of 2-pyridone structures have recently attracted a lot of attention due to their uses as synthetic intermediates and their biological importance.
Mostafa M.K. Amer, Maged A. Aziz, Wesam S. Shehab, Magda H. Abdellattif, Samar M. Mouneir   +4 more
doaj   +1 more source

Azo-hydrazone tautomerism of aryl azo pyridone dyes [PDF]

Hemijska Industrija, 2013
In the last three or four decades disperse dyes derived from pyridones (in particular azo pyridone dyes) have gained in importance, and are widely used in various fields.
Mirković Jelena M., Ušćumlić Gordana S., Marinković Aleksandar D., Mijin Dušan Ž.   +3 more
doaj   +1 more source

CXXXI.—Benzeneazo-2-pyridone [PDF]

J. Chem. Soc., Trans., 1908
n ...
Mills, William Hobson, Widdows, Sibyl T.
openaire   +1 more source

Potential role of PIM1 inhibition in the treatment of SARS-CoV-2 infection

Journal of Genetic Engineering and Biotechnology, 2023
Background SARS-CoV-2 infection involves disturbing multiple molecular pathways related to immunity and cellular functions. PIM1 is a serine/threonine-protein kinase found to be involved in the pathogenesis of several viral infections. One PIM1 substrate,
Magda M. F. Ismail, Rehab R. El-Awady, Amal M. Farrag, Sara H. Mahmoud, Noura M. Abo Shama, Ahmed Mostafa, Mohamed A. Ali, Mohammed H. Rashed, Iman H. Ibrahim   +8 more
doaj   +1 more source

Cyclization of N-acetyl derivative: Novel synthesis – azoles and azines, antimicrobial activities, and computational studies

Heterocyclic Communications, 2022
2-Pyridone is considered as one of the most famous efficient pharmaceutical compounds. Many approaches were discovered to synthesize 2-pyridone. In this present research, chloroacetylation of benzylamine at simple conditions, EtONa/EtCOONa produced N ...
Hamed Eman O., Assy Mohamed G., Ouf Nabil H., Elsayed Doaa A., Abdellattif Magda H.   +4 more
doaj   +1 more source

Continuous flow synthesis of some 6- and 1,6-substituted 3-cyano-4-methyl-2-pyridones [PDF]

Journal of the Serbian Chemical Society, 2019
In this study, six 6- and 1,6-substituted-3-cyano-4-methyl-2-pyridones were synthesized in a continuous flow microreactor system. The syntheses were realized at room temperature and the obtained results were compared to those achieved within classical ...
Tadić Julijana, Mihajlović Marina, Jovanović Mića, Mijin Dušan   +3 more
doaj   +1 more source

The Thermodynamic and Kinetic Properties of 2-Hydroxypyridine/2-Pyridone Tautomerization: A Theoretical and Computational Revisit [PDF]

International Journal of Molecular Sciences, 2016
Rifaat Hilal, Saadullah Aziz, Osman I Osman   +2 more
exaly   +2 more sources

Rhodium(I)-Complexes Catalyzed 1,4-Conjugate Addition of Arylzinc Chlorides to N-Boc-4-pyridone

Molecules, 2017
Rhodium(I)-complexes catalyzed the 1,4-conjugate addition of arylzinc chlorides to N-Boc-4-pyridone in the presence of chlorotrimethylsilane (TMSCl). A combination of [RhCl(C2H4)2]2 and BINAP was determined to be the most effective catalyst to promote ...
Fenghai Guo, Matthew A. McGilvary, Malcolm C. Jeffries, Briana N. Graves, Shekinah A. Graham, Yuelin Wu   +5 more
doaj   +1 more source

Rapidly Diversifying Hydrogen‐Bonded Organic Frameworks With Permanent Porosity

Angewandte Chemie, EarlyView.
This article reviews diversifying hydrogen‐bonded organic frameworks (HOFs) with permanent porosity reported over the past 15 years, based on the molecular structures of their constituent tectons. Furthermore, several distinctive aspects and concepts are described, such as permanent porosity, isostructural (isoreticular) HOFs, and multicomponent mixed ...
Taito Hashimoto, Ichiro Hisaki
wiley   +2 more sources