Results 21 to 30 of about 9,299,574 (208)

Continuous flow synthesis of some 6- and 1,6-substituted 3-cyano-4-methyl-2-pyridones [PDF]

Journal of the Serbian Chemical Society, 2019
In this study, six 6- and 1,6-substituted-3-cyano-4-methyl-2-pyridones were synthesized in a continuous flow microreactor system. The syntheses were realized at room temperature and the obtained results were compared to those achieved within classical ...
Tadić Julijana, Mihajlović Marina, Jovanović Mića, Mijin Dušan   +3 more
doaj   +1 more source

Evidence of Counterion Size Effect on the Stability of Columnar Phase of Ionic Liquid Crystals Based on Pyridinium Salts Derived from N-3,4,5-Tri(alkyloxy)-benzyl-4-pyridones

Crystals, 2022
The synthesis and characterization of novel ionic liquid crystals based on pyridinium salts with Br− and PF6− counterions are described in this work. These pyridinium salts were derived from 4-hydroxypyridine, both by N- and O-alkylation.
Isabela Dumitru, Florentina L. Chiriac, Monica Ilis, Iuliana Pasuk, Doina Manaila-Maximean, Marin Micutz, Teodora Staicu, Viorel Cîrcu   +7 more
doaj   +1 more source

A synthesis of 2,3-dihydro-4-pyridones [PDF]

Arkivoc, 2006
The reaction of 1-alkoxy-1,4-dien-3-ones with primary amines results in the formation of dihydropyridones in good yield.
Michael Harmata, Dong Reyoul Lee
openaire   +2 more sources

Excitation Energy-Dependent Decay Dynamics of the S₁ State of N‑Methyl-2-pyridone

, 2023
The UV-induced decay dynamics of N-methyl-2-pyridone is investigated using a femtosecond time-resolved photoelectron spectroscopy method. Irradiation in the wavelength range of 339.3–258.9 nm prepares N-methyl-2-pyridone molecules with very different ...
Dongyuan Yang (8968340), Benjie Fang (17425269), Baihui Feng (17425266), Zhigang He (544691), Guorong Wu (307379), Xueming Yang (593735)   +5 more
core   +1 more source

Synthesis of 5-Aroyl-2-aryl-3-hydroxypyridin-4(1H)-ones

Molbank, 2023
A two-stage synthesis of 5-aroyl-2-aryl-3-hydroxypyridin-4(1H)-ones (56–66% overall yields) was carried out by refluxing 5-aroyl-3-(benzyloxy)-2-(het)aryl-4H-pyran-4-ones with ammonium acetate in AcOH and subsequent debenzylation.
Elena V. Steparuk, Dmitrii L. Obydennov, Vyacheslav Y. Sosnovskikh   +2 more
doaj   +1 more source

The Construction of Polycyclic Pyridones via Ring-Opening Transformations of 3-hydroxy-3,4-dihydropyrido[2,1-c][1,4]oxazine-1,8-diones

Molecules, 2023
This work describes the synthesis of 3-hydroxy-3,4-dihydropyrido[2,1-c][1,4]oxazine-1,8-diones, their tautomerism, and reactivity towards binucleophiles. These molecules are novel and convenient building-blocks for the direct construction of biologically
Viktoria V. Viktorova, Elena V. Steparuk, Dmitrii L. Obydennov, Vyacheslav Y. Sosnovskikh   +3 more
doaj   +1 more source

Reactions of Trifluorotriacetic Acid Lactone and Hexafluorodehydroacetic Acid with Amines: Synthesis of Trifluoromethylated 4-Pyridones and Aminoenones

Molecules, 2022
Dehydroacetic acid and triacetic acid lactone are known to be versatile substrates for the synthesis of a variety of azaheterocycles. However, their fluorinated analogs were poorly described in the literature.
Vladislav V. Fedin, Sergey A. Usachev, Dmitrii L. Obydennov, Vyacheslav Y. Sosnovskikh   +3 more
doaj   +1 more source

Potential role of PIM1 inhibition in the treatment of SARS-CoV-2 infection

Journal of Genetic Engineering and Biotechnology, 2023
Background SARS-CoV-2 infection involves disturbing multiple molecular pathways related to immunity and cellular functions. PIM1 is a serine/threonine-protein kinase found to be involved in the pathogenesis of several viral infections. One PIM1 substrate,
Magda M. F. Ismail, Rehab R. El-Awady, Amal M. Farrag, Sara H. Mahmoud, Noura M. Abo Shama, Ahmed Mostafa, Mohamed A. Ali, Mohammed H. Rashed, Iman H. Ibrahim   +8 more
doaj   +1 more source

Crystal structure of N-[6-amino-5-(benzo[d]thiazol-2-yl)-3-cyano-4-methylsulfanyl-2-oxo-1,2-dihydropyridin-1-yl]-4-methylbenzenesulfonamide dimethylformamide monosolvate

Acta Crystallographica Section E: Crystallographic Communications, 2017
In the title compound, C21H17N5O3S3·C3H7NO, the toluenesulfonamide ring and the combined ring system involving the pyridone and benzothiazole rings subtend an interplanar angle of 39.86 (4)°.
Rasha A. Azzam, Galal H. Elgemeie, Rasha E. Elsayed, Peter G. Jones   +3 more
doaj   +1 more source

Crystal Chemistry of Zinc Quinaldinate Complexes with Pyridine-Based Ligands

Crystals, 2018
Substitution of methanol in [Zn(quin)2(CH3OH)2] (quin− denotes an anionic form of quinoline-2-carboxylic acid, also known as quinaldinic acid) with pyridine (Py) or its substituted derivatives, 3,5-lutidine (3,5-Lut), nicotinamide (Nia), 3 ...
Barbara Modec
doaj   +1 more source