Results 151 to 160 of about 9,301,767 (216)

An Imidazo[2,1-b][1,3,4]thiadiazole Derivative Inhibits the Virulence Factor α-Hemolysin by Blocking the Pullout of Its Stem Domain. [PDF]

ChemMedChem
Korotkov VS, Lukat P, Di Lucrezia R, Shekhar A, Degenhart C, Diestel R, Bilitewski U, Dinkel K, Blankenfeldt W, Brönstrup M.   +9 more
europepmc   +1 more source

Influence of Available Hydrophobic Interactions in New 2‑(Propylthio)‑<i>N</i>‑(1,3,4-thiadiazol-2-yl)nicotinamide Pharmacophore and Evaluation of Its Therapeutic Potential. [PDF]

ACS Omega
Nachimuthu L, Desikan R.
europepmc   +1 more source

Studies on the Selective Toxicity. VIII. : Biological Activities of 1, 2, 4-Thiadiazole Derivatives

YAKUGAKU ZASSHI, 1968
TERUHISA NOGUCHI, YOSHINOBU HASHIMOTO, TOSHIRO MORI, SABURO KANO, KOOSHIN MIYAZAKI   +4 more
openaire   +2 more sources

Unanticipated Reactivity toward Nucleophilic Attack in the Synthesis of Saccharyl-1,3,4-Thiadiazolyl Conjugates: Structure and Mechanistic Insights. [PDF]

J Org Chem
Guerreiro BEC, Carvalho DF, Coelho JAS, Paixão JA, Frija LMT, Cristiano MLS.   +5 more
europepmc   +1 more source

Design, synthesis and antiproliferative, apoptotic, and immunomodulatory properties of new heteroaryl pyridine-linked 1,2,4-oxadiazoles as prospective dual EGFR/BRAF^V600E inhibitors. [PDF]

RSC Adv
Gomaa HAM, Shaker ME, Alzarea SI, Alatwi E, Mohamed FAM, Abdullah Alzahrani AY, Alyami BA, Bräse S, Rabea SM, Youssif BGM.   +9 more
europepmc   +1 more source

Antimicrobial Activity of 1,3,4-Thiadiazole Derivatives. [PDF]

Pharmaceuticals (Basel)
Górecki S, Kudelko A, Olesiejuk M.
europepmc   +1 more source

Interpretable QSAR, External PubChem Validation, and Coordination-Aware Docking Enable Tiered Prioritization of Carbonic Anhydrase I Inhibitors. [PDF]

Pharmaceuticals (Basel)
Elsayad AM, Elsayad KA.
europepmc   +1 more source

Novel 3‑Heteroaryl Pyrrolidine and Piperidine Compounds as Orexin Receptor Agonists for Treating Sleep Disorders, namely, Narcolepsy and Hypersomnia. [PDF]

ACS Med Chem Lett
Sabnis RW.
europepmc   +1 more source

An exploration of potent antileishmanial agents derived from quinoline-thiazole and thiadiazole hybrids, targeting DHFR-TS and PTR1: design, synthesis, and computational analyses. [PDF]

RSC Med Chem
Rashdan HRM, Bekhit AA, Furlan V, Amagase K, Elshamy AI, Elfar N, Abdo MR, Ibrahim TM, Bren U, Eldehna WM, Sabt A.   +10 more
europepmc   +1 more source

Synthetic Strategies of Fused Triazole Frameworks: A Comprehensive Review. [PDF]

ACS Omega
Tamminana R, Mohammed A.
europepmc   +1 more source