Results 51 to 60 of about 9,301,767 (216)
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2020 Analysis of the literature over the past decade has shown that the chemistry of 1,2,4-triazole and 1,3,4-thiadiazole attracts considerable interest from scientists around the world because of the many valuable properties of compounds of this class ...
A. S. Hotsulia , S. O. Fedotov
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5-(4-Bromo-2-nitrophenyl)-1,3,4-thiadiazol-2-amine
Acta Crystallographica Section E, 2011 The title compound, C8H5BrN4O2S, was synthesized by the reaction of 4-bromo-2-nitrobenzoic acid with thiosemicarbazide. The dihedral angle between the thiadiazole and benzene rings is 40.5 (2)°.
Jian-qiang Zhang +4 more
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Dual‐Module Near‐Infrared Fluorophores Discovery System via Knowledge Transfer
Advanced Science, EarlyView.This study presents a dual‐module deep learning system for the design of near‐infrared (NIR) fluorophores. A large molecular library is generated and analyzed, leading to the suggestions of promising candidates. The effectiveness of the system is further validated through the synthesis, characterization, and in vivo imaging, demonstrating its potential
Yixin Zhu +7 more
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3-[5-(4-Fluorophenyl)-1,3,4-thiadiazol-2-yl]-2-(4-methoxyphenyl)-1,3-thiazolidin-4-one
Acta Crystallographica Section E, 2008 The title compound, C18H14FN3O2S2, was synthesized by the reaction of 5-(4-fluorophenyl)-N-(4-methoxybenzylidene)-1,3,4-thiadiazol-2-amine and mercaptoacetic acid. The thiazolidinone ring adopts a twist conformation.
Li-He Yin +4 more
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Triazolo [3, 4-b] [1, 3, 4] thiadiazoles
, 1982 Chemistry Department, Panjab University, Chandigarh- 160 014 Manuscript received 29 September 1981, accepted 11 March 1982 Triazolo [3, 4-b] [1, 3, 4 ...
H. K. GAKHAR +2 more
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Novel Synthetic Derivatives of Substituted Amino -1, 2, 4-Thiadiazoles
International Journal of Chemical and Physical Sciences, 2012 A novel series of 3-amino-5-substituted amino-1,2,4-thiadiazoles (5a-f) and 3substituted thiocarbamido-5-substituted amino-1,2,4-thiadiazoles (6a-f) have been obtained by the oxidative cyclization of 1-substituted-3-formamidinothiocarbamide 1 (3af) and 1,3-bis(substitutedthioamido)-guanidine 1 (4a-f) with bromine respectively.
M.E. Shelke, J.S. Waghmare
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Synthesis and Study of Some fused Substituted 1,3,4-Thiadiazoles and 1,2,4-Triazoles from 4-Chloro- phenoxy acetic acid and 2,4-dichlorophenoxy acetic acid [PDF]
مجلة التربية والعلم, 2020 In this work the synthesis of some substituted 1,2,4-triazoles and five ring system's reported. 2-(4-Chlorophenoxy) acetic acid (S1) was synthesis from corresponding substituted phenol by its reaction with chloroacetic acid in sodium hydroxide solution ...
Mudhar Othman
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Synthesis and Biological evalution of some substituted 2-dibenzyl amino 1,3,4-oxadiazoles , thiadiazoles and 1,2,4-triazoles [PDF]
مجلة التربية والعلم, 2013 In this paper the synthesis of some substituted 2-dibenzyl 1,3,4-oxadiazole, thiadiazole and 1,2,4-triazoles derived from dibenzyl amine is reported scheme-1.
Khalid Daoud, Shaima Ismmaeel
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Discovery of CRBN‐based molecular glue degraders targeting WIZ transcription factor
Bulletin of the Korean Chemical Society, EarlyView.This work reports the discovery of 9l, a novel cereblon‐based molecular glue degrader which targets the WIZ transcription factor. Compound 9l facilitates WIZ‐CRBN ternary complex formation to degrade WIZ, subsequently inducing γ‐globin expression in HUDEP‐2 cells and highlighting its potential as a sickle cell disease therapy.
Tae‐Jun Kim +8 more
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Molecules, 2023 Palladium-catalyzed direct (het)arylation reactions of strongly electron-withdrawing tricyclic benzo[1,2-d:4,5-d′]bis([1,2,3]thiadiazole) and its 4,8-dibromo derivative were studied; the conditions for the selective formation of mono- and bis-aryl ...
Timofey N. Chmovzh +3 more
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