Results 211 to 220 of about 12,908,442 (282)

Adenine nucleotide translocator and ATP synthase cooperate in mediating the mitochondrial permeability transition

The Journal of Physiology, EarlyView.
Abstract figure legend Both ATP synthase and adenine nucleotide translocator (ANT) play key roles in mediating the permeability transition. The contribution of ANT becomes evident in the presence of atractylate (ATR) at pH 6.5, a condition that prevents ATP synthase channel activity. At pH 7.4, this effect is minimal, suggesting a critical role for ATP
Ludovica Tommasin, Andrea Carrer, Federica Boscolo Nata, Elena Frigo, Federico Fogolari, Giovanna Lippe, Michela Carraro, Paolo Bernardi   +7 more
wiley   +1 more source

Exploring the Antitubercular, Antimicrobial Potency, ADME-T Calculations and Docking Studies of 1,2,4-Triazole-Bearing Benzimidazoles. [PDF]

Chem Biodivers
Shaik KM, Pandurangan K, Bhoomandla S, Mendam K, Ullapu PR.   +4 more
europepmc   +1 more source

Mitochondrial permeability transition in skeletal muscle phenocopies muscle alterations seen in cancer cachexia and other wasting conditions

The Journal of Physiology, EarlyView.
Abstract figure legend Skeletal muscle wasting conditions are characterized by muscle fibre atrophy, mitochondrial respiratory dysfunction, mitochondrial depletion and fragmentation of acetylcholine receptor (AChR) cluster at the neuromuscular junction.
Maya Semel, Cole Lukasiewicz, Sarah Skinner, Mark R. Viggars, Sung Gi Noh, Martin Picard, Abbey‐Gale Mannings, Michael S. Cohen, Dennis W. Wolan, Terence E. Ryan, Russell T. Hepple   +10 more
wiley   +1 more source

Design, Synthesis, and Evaluation of New 1,4-Naphthoquinone-1,2,3-triazoles as Antimalarial Agents. [PDF]

Chem Biodivers
Rezainia L, Sayahi MH, Vernousfaderani EK, Mirfazli SS, Morshedsolouk MH, Dastyafteh N, Nateghpour M, Farivar L, Saeedi M, Hanifian H, Mohebali M, Shafiee SM, Hassanpour G, Mahdavi M.   +13 more
europepmc   +1 more source

Legacy hexaconazole and tricyclazole residues hinder organic transition in paddy rice cultivation

Agricultural &Environmental Letters, Volume 11, Issue 2, December 2026.
Hexaconazole and tricyclazole residues persisted in paddy soil throughout the three consecutive growing seasons after a single foliar application. These findings, combined with potential animal feed risks from contaminated rice straw, indicate that the current 2‐year organic transitional period is insufficient, necessitating extended conversion periods
Suin Cho, Hye‐In Joe, Tae‐Hwa Kim, Jong‐Woo Park, Byeong‐Jin Bae, Byeung‐Kon Shin, Jeong‐In Hwang   +6 more
wiley   +1 more source

Coumarin derivatives as promising anticancer drugs: a comprehensive review from synthesis to anticancer applications. [PDF]

RSC Adv
Suo A, Xu M, Yang M, Marković Z, El-Seedi HR, Guo M.   +5 more
europepmc   +1 more source

Real‐World Survival Outcomes of Venetoclax Combination Therapies in Acute Myeloid Leukemia: Impact of Minimal Residual Disease Status and Antifungal Prophylaxis

Hematological Oncology, Volume 44, Issue 6, November 2026.
ABSTRACT In recent years the addition of the oral BCL2 inhibitor venetoclax to hypomethylating agents (HMAs) has emerged as the standard‐of‐care for patients with acute myeloid leukemia (AML) who are not fit for intensive chemotherapy, significantly improving survival and quality‐of‐life.
Mariarita Sciumè, Alessandro Bosi, Alfredo Marchetti, Fabio Serpenti, Pasquale De Roberto, Sonia Fabris, Francesco Versino, Elena Tagliaferri, Francesco Passamonti, Nicola Stefano Fracchiolla   +9 more
wiley   +1 more source

Multidentate Triazole Coordination Unlocks Color-Tunable Plasmonic Gold Nanoparticle Films to Achieve High Catalytic Performance. [PDF]

Small Methods
Li T, Cao J, Deng Z, Chen Y, Ye Y, Guo Z, Li Y.   +6 more
europepmc   +1 more source

Evaluation of DNA/Chromosome Integrity and Cell Death in Human Metabolically Noncompetent and Competent Cells Exposed to N′‐(3,5‐Difluorobenzylidene)Pyridine‐4‐Carbohydrazide

Journal of Applied Toxicology, Volume 46, Issue 11, Page 4076-4084, November 2026.
ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos, Jéssica Natalia Barbosa de Almeida, Camila Cavalleiro Frias, Wanda Pereira Almeida, Edson Luis Maistro   +4 more
wiley   +1 more source

Pathogenesis and Triazole Resistance in <i>Aspergillus fumigatus</i>: A Narrative Review Across the Host Immune Spectrum and One Health Context. [PDF]

Infect Drug Resist
Chen T, Yao Y, Chen J, Lv H, Nan P.
europepmc   +1 more source