Results 191 to 200 of about 12,908,442 (282)

Evolution of Dermatophytic Fungi: Anthropogenic and Biogenic Environmental Factors

International Journal of Dermatology, EarlyView.
ABSTRACT Climate change presents new challenges to dermatologic care, ranging from anthropogenic factors, such as pollution that select for extremotolerant and potentially antifungal‐resistant fungi, to biogenic factors that can drive zoonotic outbreaks, which have received increased attention since the SARS‐CoV‐2 pandemic.
Aditya K. Gupta, Tong Wang, Richard C. Summerbell   +2 more
wiley   +1 more source

Genetic diversity and antifungal susceptibility among ecological niche populations of Aspergillus flavus in Yaoundé, Cameroon. [PDF]

PLoS One
Kuate MPN, Ramkumar K, Dalmieda J, Nadeem J, Hemmati J, Nkenfou CN, Ndip RN, Xu J.   +7 more
europepmc   +1 more source

Systemic treatment of cutaneous leishmaniasis: A systematic review and meta‐analysis

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This systematic review and meta‐analysis assessed systemic treatments for cutaneous leishmaniasis across 83 studies and 4603 patients. Treatment efficacies of meglumine antimoniate, miltefosine, azoles, pentamidine, and liposomal amphotericin B varied by region and species. Miltefosine showed consistent evidence across multiple settings.
Maximilian Egg, Dennis Wienand, Lucie Harpain, Marie‐Luise Brunner‐Kovarik, Julia Walochnik, Markus Wiesmueller, Amélie Hampel, Tibor Spath, Lukas Trnka, Judit Simon, Alessandra Handisurya   +10 more
wiley   +1 more source

Design and synthesis of 1,3,4-oxadiazole-tethered <i>N</i>-substituted isatin hybrids as SARS-CoV-2 main protease inhibitors: biological evaluation, kinetic investigation, and <i>in silico</i> studies. [PDF]

RSC Adv
Al-Warhi T, Islam Mukim MS, Elsayed ZM, Omar YM, Elimam DM, Shaldam MA, El-Damasy AK, Elbadawi MM, Tawfik HO, Song DG, Eldehna WM.   +10 more
europepmc   +1 more source

Consensus recommendations for Trichophyton indotineae: A modified Delphi study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
A modified Delphi consensus for suspected terbinafine‐resistant T. indotineae: confirm dermatophytes with KOH microscopy/culture and species‐level PCR/ITS sequencing. Itraconazole is recommended as first‐line systemic therapy, with luliconazole 1% cream as a topical adjunct. Posaconazole may be considered if itraconazole fails, while keeping antifungal
Aditya K. Gupta, Mesbah Talukder, Ditte Marie L. Saunte, Roderick James Hay, Michael Arabatzis, Avrom S. Caplan, Eran Galili, Eckart Haneke, Matilde Iorizzo, Riad Kassem, Ananta Khurana, Shari R. Lipner, Anna Lyakhovitsky, Brian W. Morrison, Vincent Piguet, Bianca Maria Piraccini, Carmen Rodríguez‐Cerdeira, Avner Shemer, Michela Starace, Olav Sundnes, Antonella Tosti   +20 more
wiley   +1 more source

Design, synthesis, molecular modelling and biological evaluation of oxiconazole-based 1,2,3-triazoles as dually acting antifungal and antitumor agents. [PDF]

Sci Rep
Ismail AE, Ashmawy MI, Shehat MG, Al-Seqely MA, Badr MH, Rostom SAF.   +5 more
europepmc   +1 more source

CP32, a novel anti‐oomycete cyclic peptide, interferes with cell‐wall deposition in Phytophthora infestans

Journal of Integrative Plant Biology, EarlyView.
The small cyclic peptide CP32 effectively inhibits Phytophthora infestans, the causal agent of potato and tomato late blight. Combined biochemical and phenotypic analyses demonstrate that CP32 disrupts cell wall biosynthesis, a key process in pathogen infection, resulting in a marked reduction of disease symptoms in plants.
Demetrio Marcianò, Stefano Rosa, Elena Marone Fassolo, Chiara Bertaso, Andrea Tagliani, Nina Gauri Capra, Federico Ballabio, Chiara Mizzotti, Giulia Rizzi, Sadia Fida Ullah, Lisa Kappel, Lucia Feni, Luca Tadini, Louise Jane Gourlay, Rosaria Russo, Vincent Bulone, Sabrina Pricl, Sandrine Ongeri, Sara Pellegrino, Carlo Camilloni, Silvia Laura Toffolatti, Vaibhav Srivastava, Paolo Pesaresi, Simona Masiero   +23 more
wiley   +1 more source

Synthesis and Broad-Spectrum Antiviral Evaluation of Novel 1,2,3-Triazole-Quinoline Derivatives Targeting SARS-CoV-2, Influenza, DENV-2, and CHIKV. [PDF]

Viruses
de Carvalho AS, Fintelman-Rodrigues N, de Camargo VTD, Silva-Trujillo L, de Freitas CS, Graciano IA, de Souza AS, de Assis CB, Chaves OA, da Silva FC, Ferreira VF, Souza TML.   +11 more
europepmc   +1 more source

1, 3, 5-Triphenyl-1, 2, 4-triazoleおよび 3, 5-diphenyl-1, 2, 4-triazole

Journal of Synthetic Organic Chemistry, Japan, 1970
openaire   +1 more source

Platelet‐Rich Fibrins as Local Drug‐Delivery Carriers

Journal of Periodontal Research, EarlyView.
Autologous platelet concentrates (APCs), particularly platelet‐rich fibrin (PRF), act as biologically active fibrin scaffolds, capable of entrapping and gradually releasing therapeutic agents in oral and periodontal therapy. The incorporation of bioactive compounds, such as antibiotics, antifungals, vitamins, antidiabetic drugs, and exosomes, enhances ...
Karim M. Fawzy El‐Sayed, Christof E. Dörfer   +1 more
wiley   +1 more source