The key cytochrome P450 gene GmSUR2a enables soybeans to withstand destructive submergence stress. By lowering the level of the plant hormone indole‐3‐acetic acid, this gene improves soybean survival and increases field yield. It offers an important tool for breeding stress‑resilient soybeans, securing food production against extreme weather conditions.
Yangyang Chen +14 more
wiley +1 more source
Azole Resistance in <i>Aspergillus fumigatus</i> From Diverse Environments in Ohio, United States, Is Primarily Driven by TR<sub>34</sub>/L98H and TR<sub>46</sub>/Y121F/T289A Environmental Signatures. [PDF]
Paul RA +5 more
europepmc +1 more source
The small cyclic peptide CP32 effectively inhibits Phytophthora infestans, the causal agent of potato and tomato late blight. Combined biochemical and phenotypic analyses demonstrate that CP32 disrupts cell wall biosynthesis, a key process in pathogen infection, resulting in a marked reduction of disease symptoms in plants.
Demetrio Marcianò +23 more
wiley +1 more source
Synthesis of Novel d-Glucopyranuronamide-Based Nucleos(t)ide Analogs Bearing (Triazolyl)methyl Phosph(on)ate Motifs With Anticancer and Antibacterial Potential. [PDF]
Manuel DM +5 more
europepmc +1 more source
Platelet‐Rich Fibrins as Local Drug‐Delivery Carriers
Autologous platelet concentrates (APCs), particularly platelet‐rich fibrin (PRF), act as biologically active fibrin scaffolds, capable of entrapping and gradually releasing therapeutic agents in oral and periodontal therapy. The incorporation of bioactive compounds, such as antibiotics, antifungals, vitamins, antidiabetic drugs, and exosomes, enhances ...
Karim M. Fawzy El‐Sayed +1 more
wiley +1 more source
Design and Synthesis of Bis-Triazole-Linked Benzenesulfonamides as Selective Carbonic Anhydrase IX/XII Inhibitors with Chemosensitizing Activity. [PDF]
Roshdy E +11 more
europepmc +1 more source
Natural Variation in GmSL20 Improves Seed Size and Quality in Soybean
ABSTRACT Seed size plays an important role in determining crop yield, yet the genetic mechanisms underlying the regulation of this agronomic trait remain incompletely understood in soybean. Here, we perform a genome‐wide association study mapping with seed length variations and identify a major quantitative trait locus (QTL) on chromosome 20, named ...
Yuechuan Luo +12 more
wiley +1 more source
β-Mannosyl Triazoles as Mimics of Galactosyl Galectin-3 and Galectin-9 N-Terminal Domain Inhibitors. [PDF]
Sjövall F, Nilsson UJ.
europepmc +1 more source
Bridging the gap in Alzheimer's therapy: strategic design and SAR evolution of coumarin-based hybrids as potent MTDLs. [PDF]
El-Mokaddem OK +3 more
europepmc +1 more source
Prevalence of Antimicrobial Use in Small Animal Dermatology Referral Practices in the United States
ABSTRACT Background Antimicrobial resistance is a critical global health concern driven by antimicrobial use. Dermatological conditions are common reasons for antimicrobial prescriptions in small animal practice, yet data on prescribing patterns in veterinary dermatology referral settings are lacking. Hypothesis/Objectives To characterise the frequency,
Domenico Santoro +2 more
wiley +1 more source

