The search for new 4-amino-5-methyl-4H-1,2,4-triasole-3-thion derivatives with diuretic activity
Zaporožskij Medicinskij Žurnal, 2018 1,2,4-Triazole derivatives have been widely used in medical practice due to their wide spectrum of biological activities and low toxicity, as they have 1,2,4-triazole cycle in their structure.
T. V. Kravchenko
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Study acute toxicity of 4-(R-amino)-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazole-3-thiol in vivo
Фармацевтичний журнал, 2018 Typically, the system is already known are used as the core for a new substance, which have already proved themselves as potential drugs. So one of these is 1,2,4-triazole ring.
A. A. Safonov
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Arab Journal of Basic and Applied Sciences, 2023 The study investigated the corrosion-inhibitory properties of three synthetic triazole Mannich bases on C1018 carbon steel using various electrochemical techniques.
N. Phadke Swathi +7 more
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Regioselective synthesis, antitumor and antioxidant activities of some 1,2,4-triazole derivatives based on 4-phenyl-5-(quinolin-8-yloxy)methyl-4H-1,2,4-triazole-3-thiol [PDF]
, 2017 Regioselective synthesis of some triazole derivatives 4–18 was achieved from the versatile, readily accessible 4-phenyl-5-(quinolin-8-yloxy)methyl-4H-1,2,4-triazole-3-thiol/thione 3.
M. S. Amine (3610862) +2 more
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Фармацевтичний журнал, 2018 The large interest in the plan of search biologically of active agents is caused by the heterocyclic system of 1,2,4-triazole, due to high biological activity, and by the low indexes of toxicness, that inherent it to the structural analogues.
Т. М. Kaplaushenko +2 more
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Regioselective formation of new 3-S-alkylated-1,2,4-triazole-quinolones [PDF]
, 2021 Regioselective synthesis of quinolone-1,2,4-triazoles was established starting from 4-hydroxyquinol-2-ones. The strategy started by the reaction of ethyl bromoacetate with 4-hydroxyquinoline to give the corresponding ethyl oxoquinolinyl acetates, which ...
Alan B. Brown (11775964) +7 more
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Anticonvulsant activity 2-((5-(3-(4-fluorophenyl)-4-R2-1,2,4-triazole-3-yl)-thio)-1-arylethanone
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2019 The aim of work is to study of the anticonvulsant activity of 2-((5-(3-,4-fluorophenyl)-4-R2-1,2,4-triazole-3-yl)thio)-1-aryletanones, the establishment of some laws between the structure of compounds and their activity. Materials and methods.
O. A. Bihdan
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Triazole-Containing [FeFe] Hydrogenase Mimics: Synthesis and Electrocatalytic Behavior [PDF]
, 2019 Through a Cu-catalyzed Huisgen cycloaddition between terminal alkynes and azides (CuAAC) reaction, azide [(μ-SCH2)2N(4-N3C6H4)Fe2(CO)6] has demonstrated to be a robust and versatile reagent able to incorporate the [(μ-SR)2Fe2(CO)6] fragment on a wide ...
Luis Casarrubios (1483762) +7 more
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Evaluation Of Antioxidant Activity Of 1, 2, 4-Triazole Derivatives With Morpholine Moiety
Hacettepe University Journal of the Faculty of Pharmacy, 2022 The aim of the work was to study the antioxidant activity of 4-R-3- (morpholinomethyl)-4H-1,2,4-triazole-5-thioles and their alkyl derivatives in vitro using the method of non-enzymatic initiation of lipid peroxidation. Among the 45 compounds studied, 8 showed varying degrees of AOA.
SHCHERBYNA, Roman +5 more
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From Mono to Tris-1,2,3-triazole-Stabilized Gold Nanoparticles and Their Compared Catalytic Efficiency in 4‑Nitrophenol Reduction [PDF]
, 2016 Mono-, bis-, and tris-1,2,3-triazole ligands are used for the stabilization of gold nanoparticles (AuNPs), and the catalytic activities of these AuNPs in 4-nitrophenol reduction by NaBH4 in water are compared as well as with polyethylene glycol 2000 (PEG)
Sergio Moya (1353486) +7 more
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