Results 11 to 20 of about 2,478,339 (383)

MicroRNA‐410 serves as a candidate biomarker in hypoxic‐ischemic encephalopathy newborns and provides neuroprotection in oxygen‐glucose deprivation‐injured PC12 and SH‐SY5Y cells

Brain and Behavior, 2021
Background MicroRNA‐410 (miR‐410) has been found to be deregulated in neonatal hypoxic‐ischemic encephalopathy (HIE). However, the clinical significance and biological function of miR‐410 remain largely elusive.
Qinghong Meng, Peipei Yang, Yuanyuan Lu
doaj   +2 more sources

MicroRNA-410-3p modulates chondrocyte apoptosis and inflammation by targeting high mobility group box 1 (HMGB1) in an osteoarthritis mouse model

BMC Musculoskeletal Disorders, 2020
Background Osteoarthritis (OA) is the most prevalent type of arthritis, which commonly involves inflammation in the articular cartilage in OA pathogenesis.
Hong Pan, Huming Dai, Linzhi Wang, Silong Lin, Yuefeng Tao, Yi Zheng, Renyi Jiang, Fan Fang, Yifan Wu   +8 more
doaj   +2 more sources

Trophoblast-derived miR-410-5p induces M2 macrophage polarization and mediates immunotolerance at the fetal-maternal interface by targeting the STAT1 signaling pathway

Journal of Translational Medicine
Background Macrophages phenotypic deviation and immune imbalance play vital roles in pregnancy-associated diseases such as spontaneous miscarriage.
Jing Yang, Longfei Li, Linlin Wang, Ruizhi Chen, Xiaobing Yang, Juanhua Wu, Gang Feng, Jinli Ding, Lianghui Diao, Jiao Chen, Jing Yang   +10 more
doaj   +2 more sources

MiR-410 Acts as a Tumor Suppressor in Estrogen Receptor-Positive Breast Cancer Cells by Directly Targeting ERLIN2 via the ERS Pathway

Cellular Physiology and Biochemistry, 2018
Background/Aims: Endoplasmic reticulum lipid raft-associated 2 (ERLIN2) is reported to be overexpressed in human breast cancer cells and plays an important role in cell proliferation.
Hewen Wu, Junli Li, En’en Guo, Suxia Luo, Guohui Wang   +4 more
doaj   +2 more sources

LINC00680 Promotes the Progression of Non-Small Cell Lung Cancer and Functions as a Sponge of miR-410-3p to Enhance HMGB1 Expression

OncoTargets and Therapy, 2020
Purpose LINC00680 was reported to be involved in various cancers through multiple mechanisms. Therefore, we intended to investigate its role in the progression of non-small cell lung cancer (NSCLC).
Huan Wang, Ling Feng, Zheng Yan, Wei Li, Liu L, Sheng Xie, Ying Zhou, Chao Chen, Dan Cheng   +8 more
openalex   +3 more sources

Detection and Analysis of Corrosion and Contact Resistance Faults of TiN and CrN Coatings on 410 Stainless Steel as Bipolar Plates in PEM Fuel Cells

Italian National Conference on Sensors, 2022
Bipolar Plates (BPPs) are the most crucial component of the Polymer Electrolyte Membrane (PEM) fuel cell system. To improve fuel cell stack performance and lifetime, corrosion resistance and Interfacial Contact Resistance (ICR) enhancement are two ...
M. Forouzanmehr, Kazem Reza Kashyzadeh, A. Borjali, Anastas Ivanov, Mosayeb Jafarnode, T. Gan, Bin Wang, M. Chizari   +7 more
semanticscholar   +1 more source

Extracellular Vesicle-Derived microRNA-410 From Mesenchymal Stem Cells Protects Against Neonatal Hypoxia-Ischemia Brain Damage Through an HDAC1-Dependent EGR2/Bcl2 Axis

Frontiers in Cell and Developmental Biology, 2021
Hypoxia-ischemia brain damage (HIBD) is a neurological disorder occring in neonates, which is exacerbated by neuronal apoptosis. Mesenchymal stem cells (MSCs)-derived extracellular vesicles (EVs) have been proposed as a promising strategy for treating or
Jun Han, Si Yang, Xiaosheng Hao, Bo Zhang, Hongbo Zhang, Cuijuan Xin, Y. Hao   +6 more
semanticscholar   +1 more source

Long non-coding RNA OIP5-AS1 regulates smoke-related chronic obstructive pulmonary disease via targeting micro RNA -410-3p/IL-13

Bioengineered, 2021
This investigation aimed to assess the levels of serum OIP5-AS1 and micro RNA-410-3p (miR-410-3p) in patients with chronic obstructive pulmonary disease (COPD) and their potential molecular mechanism. The levels of OIP5-AS1 and miR-410-3p as well as mRNA
Wenbo Hao, Fei Lin, Hanbing Shi, Zhanjiang Guan, Yunfei Jiang   +4 more
semanticscholar   +1 more source

miR-410 induces both epithelial–mesenchymal transition and radioresistance through activation of the PI3K/mTOR pathway in non-small cell lung cancer

Signal Transduction and Targeted Therapy, 2020
Radiotherapy remains one of the major treatments for non-small cell lung cancer (NSCLC) patients; whereas intrinsic or acquired radioresistance limits its efficacy. Nevertheless, most studies so far have only focused on acquired resistance.
Yue Yuan, H. Liao, Q. Pu, Xixian Ke, Xueting Hu, Yongfang Ma, Xinmei Luo, Q. Jiang, Y. Gong, Min Wu, Lunxu Liu, Wen Zhu   +11 more
semanticscholar   +1 more source

miR-410-3P inhibits adipocyte differentiation by targeting IRS-1 in cancer-associated cachexia patients

Lipids in Health and Disease, 2021
Cancer-associated cachexia (CAC) is a metabolic syndrome characterized by progressive depletion of adipose and muscle tissue that cannot be corrected by conventional nutritional therapy.
Diya Sun, Zuoyou Ding, Lei Shen, Fan Yang, Jun Han, Guohao Wu   +5 more
semanticscholar   +1 more source