Results 81 to 90 of about 23,419 (256)

Validation of two accelerated 4D flow MRI sequences at 3 T: a phantom study

European Radiology Experimental, 2019
Background Four-dimensional (4D) flow magnetic resonance imaging (MRI) sequences with advanced parallel imaging have the potential to reduce scan time with equivalent image quality and accuracy compared with standard two-dimensional (2D) flow MRI.
Sebastian Ebel, Lisa Hübner, Benjamin Köhler, Siegfried Kropf, Bernhard Preim, Bernd Jung, Matthias Grothoff, Matthias Gutberlet   +7 more
doaj   +1 more source

Personalized Network‐Guided Neuromodulation Enhances Human Working Memory

Advanced Science, EarlyView.
A personalized neuromodulation framework combining individualized functional brain network targeting with real‐time neural decoding is introduced. Using concurrent TMS–fMRI, participant‐specific stimulation targets and optimal frequencies are identified. Only optimal‐frequency stimulation improves working memory across sessions.
Ahsan Khan, Hongming Li, Camille Blaine, Julie Grier, Ethan Hammett, Almaris Figueroa‐Gonzalez, Sarai Garcia, Romain Duprat, Justin Reber, Joseph Deluisi, Christos Davatzikos, Theodore D. Satterthwaite, Yong Fan, Desmond J. Oathes   +13 more
wiley   +1 more source

4D flow MRI—Automatic assessment of blood flow in cerebral arteries

Biomedical Physics & Engineering Express, 2018
Objective: With a 10-minute 4D flow MRI scan, the distribution of blood flow to individual arteries throughout the brain can be analyzed.
Tora Dunås, Anders Wåhlin, Laleh Zarrinkoob, Jan Malm, Anders Eklund   +4 more
openaire   +2 more sources

The role of 4D flow MRI in deep vein thrombosis research

Meta-Radiology
Four-dimensional (4D) flow Magnetic Resonance Imaging (MRI) technology has emerged as a valuable tool in angiography, offering unique insights into the hemodynamics and flow patterns. This research aims to explore the role of 4D flow MRI in advancing our
Meizhi Li, Shangjie Wu, Xiao Liang, Chuanqi Gao, Muhua Hu, Zhu Chen, Pei He, Tingting Jia, Li Xiong   +8 more
doaj   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

Advanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon, Mireille Elodie Tsitokana, Ugo Guy Alenda, Yen‐Ling Lian, Clémentine Eva Philibert, Mathieu Oosterlaken, Marta Cimadevila, Gaëlle Dudon, Jessica Monnic, Salomé Roux, Julie Bessié, Séverine Diem, Franck Vandermoere, Laurent Prézeau, Patrick Chames, Julie Kniazeff, Sylvie Claeysen, Anaïs Menny, Jean‐Philippe Pin, Véronique Perrier, Jianfeng Liu, Philippe Rondard   +21 more
wiley   +1 more source

Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma

Hepatology, EarlyView., 2022
Steatotic HCC can be diagnosed by MRI and forms a pro‐tumor immune microenvironment with high expression of PD‐L1, M2 polarization of macrophages and activation of CAFs, which may be a good target for combined immunotherapy. Abstract Background and Aims Immunotherapy has become the standard‐of‐care treatment for hepatocellular carcinoma (HCC), but its ...
Hiroki Murai, Takahiro Kodama, Kazuki Maesaka, Shoichiro Tange, Daisuke Motooka, Yutaka Suzuki, Yasuyuki Shigematsu, Kentaro Inamura, Yoshihiro Mise, Akio Saiura, Yoshihiro Ono, Yu Takahashi, Yota Kawasaki, Satoshi Iino, Shogo Kobayashi, Masashi Idogawa, Takashi Tokino, Tomomi Hashidate‐Yoshida, Hideo Shindou, Masanori Miyazaki, Yasuharu Imai, Satoshi Tanaka, Eiji Mita, Kazuyoshi Ohkawa, Hayato Hikita, Ryotaro Sakamori, Tomohide Tatsumi, Hidetoshi Eguchi, Eiichi Morii, Tetsuo Takehara   +29 more
wiley   +1 more source

Associations between haemodynamics and wall enhancement of intracranial aneurysm

Stroke and Vascular Neurology
Background and purpose Previous studies have reported about inflammation processes (IPs) that play important roles in aneurysm formation and rupture, which could be driven by blood flow.
Peng Liu, Rui Li, Aihua Liu, Xin Tong, Xin Feng, Youxiang Li, Fei Peng, Hao Niu, Miaoqi Zhang, Yunduo Li, Huijun Chen, Baorui Zhang, Guangrong Song   +12 more
doaj   +1 more source

Bioorthogonal Fluorogenic Reporters for Noninvasive Imaging and Urinalysis of Immunotherapeutic Response in Renal Cell Carcinoma

Advanced Science, EarlyView.
This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang, Baoshuai Liang, Liangmin Fu, Weiliang Deng, Yuyan Jiang, Weiping Xu, Jinwei Chen, Ya Zhou, Ke Wu, Jiaguo Huang   +9 more
wiley   +1 more source

Modeling cerebrospinal fluid dynamics across the entire intracranial space through integration of four-dimensional flow and intravoxel incoherent motion magnetic resonance imaging

Fluids and Barriers of the CNS
Background Bidirectional reciprocal motion of cerebrospinal fluid (CSF) was quantified using four-dimensional (4D) flow magnetic resonance imaging (MRI) and intravoxel incoherent motion (IVIM) MRI.
Shigeki Yamada, Tomohiro Otani, Satoshi Ii, Hirotaka Ito, Chifumi Iseki, Motoki Tanikawa, Yoshiyuki Watanabe, Shigeo Wada, Marie Oshima, Mitsuhito Mase   +9 more
doaj   +1 more source

Evaluation of Aortic Diseases Using Four-Dimensional Flow Magnetic Resonance Imaging

Vascular Specialist International
The complex hemodynamic environment within the aortic lumen plays a crucial role in the progression of aortic diseases such as aneurysms and dissections.
Hyun Jung Koo, Hojin Ha, Gyu-Han Lee, Jong En Lee, Sang-hyub Park, Kyoung-jin Park, Joon-Won Kang, Dong Hyun Yang   +7 more
doaj   +1 more source