Results 91 to 100 of about 544,750 (281)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

The 4G/5G PAI-1 polymorphism influences the endothelial response to IL-1 and the modulatory effect of pravastatin [PDF]

, 2006
BACKGROUND: Increased plasminogen activator inhibitor (PAI-1) levels lead to impaired fibrinolytic function associated with higher cardiovascular risk. PAI-1 expression may be regulated by different inflammatory cytokines such as interleukin-1alpha (IL-1)
Belzunce, M. (Miriam), Orbe, J. (Josune), Paramo, J.A. (José Antonio), Rodriguez, J.A. (José Antonio), Roncal, C. (Carmen)   +4 more
core  

Laser‐Induced Graphene from Waste Almond Shells

Advanced Functional Materials, EarlyView.
Almond shells, an abundant agricultural by‐product, are repurposed to create a fully bioderived almond shell/chitosan composite (ASC) degradable in soil. ASC is converted into laser‐induced graphene (LIG) by laser scribing and proposed as a substrate for transient electronics.
Yulia Steksova, Anna Chiara Bressi, Marina Galliani, Attilio Marino, Gianni Ciofani, Eduardo Machado‐Charry, Hilda Gomez Bernal, Alessandra Francini, Luca Sebastiani, Francesco Greco   +9 more
wiley   +1 more source

Study of 4G/5G Mutations Prevalence in Plasminogen Activator Inhibitor-1 (PAI-1) Gene in Iranian Women with Ectopic Pregnancy [PDF]

Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2017
Background: Ectopic pregnancy is a type of pregnancy in which implantation of zygote occurs out of the uterine cavity. One of the most important problems is bleeding. On the other hand, Plasminogen Activator Inhibitor-1(PAI-1) gene is one of the involved
Zahra Sadeghi, Ahmad Ebrahimi, Fateme Davari Tanha, Seyed Yousef Seyedena   +3 more
doaj  

Index realization for automorphisms of free groups

, 2017
For any surface $\Sigma$ of genus $g \geq 1$ and (essentially) any collection of positive integers $i_1, i_2, \ldots, i_\ell$ with $i_1+\cdots +i_\ell = 4g-4$ Masur and Smillie have shown that there exists a pseudo-Anosov homeomorphism $h:\Sigma \to ...
Coulbois, Thierry, Lustig, Martin
core  

Analisis dan penilaian prestasi lengah lepas tangan menggunakan protokol pencetusan sesi (SIP) bagi sistem terintegrasi UMTS-WLAN [PDF]

, 2007
Teknologi rangkaian tanpa vvayar 4G merupakan penggabungan beberapa teknologi rangkaian capaian yang berbeza seperti rangkaian Universal Mobile Telecommunication System (UMTS) dan Rangkaian Kawasan Setempat Tanpa Wayar (WLAN).
Ab. Rahman, Munirah
core  

Biomass Native Structure Into Functional Carbon‐Based Catalysts for Fenton‐Like Reactions

Advanced Functional Materials, EarlyView.
This study indicates that eight biomasses with 2D flaky and 1D acicular structures influence surface O types, morphology, defects, N doping, sp2 C, and Co nanoparticles loading in three series of carbon, N‐doped carbon, and cobalt/graphitic carbon. This work identifies how these structural factors impact catalytic pathways, enhancing selective electron
Wenjie Tian, Jingkai Lin, Zhihao Tian, Selusiwe Ncube, Huayang Zhang, Emiliano Cortés, Hongqi Sun, Shaobin Wang   +7 more
wiley   +1 more source

MOFs and COFs in Electronics: Bridging the Gap between Intrinsic Properties and Measured Performance

Advanced Functional Materials, EarlyView.
Metal‐organic frameworks (MOFs) and covalent organic frameworks (COFs) hold promise for advanced electronics. However, discrepancies in reported electrical conductivities highlight the importance of measurement methodologies. This review explores intrinsic charge transport mechanisms and extrinsic factors influencing performance, and critically ...
Jonas F. Pöhls, R. Thomas Weitz
wiley   +1 more source

Circulating Levels of PAI-1 and SERPINE1 4G/4G Polymorphism Are Predictive of Poor Prognosis in HCC Patients Undergoing TACE

Translational Oncology, 2015
Although several molecular markers have been proposed as prognostic of disease progression in Hepatocellular carcinoma (HCC), predictive markers of response to treatment are still unsatisfactory.
Rosa Divella, Antonella Daniele, Ines Abbate, Eufemia Savino, Porzia Casamassima, Giancarlo Sciortino, Giovanni Simone, Gennaro Gadaleta-Caldarola, Vito Fazio, Cosimo Damiano Gadaleta, Carlo Sabbà, Antonio Mazzocca   +11 more
doaj   +1 more source

Creep rupture behavior of Stirling engine materials [PDF]

The automotive Stirling engine, being investigated jointly by the Department of Energy and NASA Lewis as an alternate to the internal combustion engine, uses high-pressure hydrogen as the working fluid.
Scheuerman, C. M., Stephens, J. R., Titran, R. H.   +2 more
core   +1 more source