Results 51 to 60 of about 302,140 (281)

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Intelligent Computational Model for Energy Efficiency and AI Automation of Network Devices in 5G Communication Environment

Tsinghua Science and Technology
Currently, the 4G network service has caused massive digital growth in high use. Video calling has become the go-to Internet application for many people, downloading even huge files in minutes.
Ashish Bagwari, Jaganathan Logeshwaran, M. Raja, P. Devisivasankari, Jyotshana Bagwari, Vikas Rathi, Asma Mohammed Elbashir Saad   +6 more
doaj   +1 more source

Plasminogen activator inhibitor-1 4G/5G polymorphism and retinopathy risk in type 2 diabetes: a meta-analysis

BMC Medicine, 2013
Background Mounting evidence has suggested that plasminogen activator inhibitor-1 (PAI-1) is a candidate for increased risk of diabetic retinopathy. Studies have reported that insertion/deletion polymorphism in the PAI-1 gene may influence the risk of ...
Zhang Tengyue, Pang Chong, Li Ningdong, Zhou Elaine, Zhao Kanxing   +4 more
doaj   +1 more source

Funnel plot of PAI-1 (−675 4G/4G) genotype and pre-eclampsia.

, 2013
Funnel plot of PAI-1 (−675 4G/4G) genotype and pre-eclampsia.
Sarah Bombell (282593), William McGuire (109277), Jessie A. Morgan (282592)   +2 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Meta-analysis of PAI-1 (−675 4G/4G) genotype and pre-eclampsia: recessive model.

, 2013
Meta-analysis of PAI-1 (−675 4G/4G) genotype and pre-eclampsia: recessive model.
Sarah Bombell (282593), William McGuire (109277), Jessie A. Morgan (282592)   +2 more
core   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Wireless myths, realities, and futures: from 3G/4G to optical and quantum wireless

, 2012
This paper evaluates both the operational third-generation (3G) as well as the emerging fourth-generation (4G) wireless systems and investigates new technologies that might transpire and change things in the future.
O'Brien, D., Gyongyosi, L., Haas, H., Hanzo, L., Imre, S., Rupp, M.   +5 more
core   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

4G: Expectativas, Aplicaciones y Retos Existentes en su Implementación

Prisma Tecnológico, 2016
Cada vez son mayores los requerimientos de los sistemas inalámbricos por la creciente necesidad de información diversa por parte de los usuarios. Nos encontramos actualmente en le punto de transición entre una generación de tecnología y otra. Y si bien
Francisco Tello
doaj