Results 51 to 60 of about 51,192 (201)

The Natural Product Esculetin as an Efficient Photoacid for the Visible‐Light‐Mediated Acetalization/Ketalization Reaction

ChemSusChem, Volume 19, Issue 19, 14 October 2026.
Esculetin: an efficient photoacid catalyzing acetalization/ketalization reactions. The development of photochemical protocols for the production of fine chemicals and industrially interesting products, employing sustainable catalysts under mild conditions, is of high interest.
Maria A. Theodoropoulou, E. Alexandros Routsi, Christiana Mantzourani, Olga G. Mountanea, Demeter Tzeli, Christoforos G. Kokotos, George Kokotos   +6 more
wiley   +1 more source

4H-yrittäjyys nuorten työelämätaitoja edistämässä: 4H-yrittäjien kokemukset Jyvässeudun 4H-yhdistyksen toiminnassa [PDF]

, 2019
Opinnäytetyössäni tutkin Jyvässeudun 4H-yhdityksen toimintaan kuuluvaa 4H-yrittäjyyttä. 4H-yrittäjyyden kohderyhmänä ovat 13-28-vuotiaat nuoret ja toimintaa toteuttavat 4H-yhdistykset eri puolilla Suomea.
Jokinen, Kaisa
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Metabolomics Analysis Revealed That SXZ Ameliorates Cognitive Impairment in Naturally Aged Rats by Promoting Glutathione Metabolism and Inhibiting the Ferroptosis Pathway

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
In aged rats, 6‐month SXZ treatment reversed spatial memory deficits and preserved hippocampal integrity. Mechanistic assays show that SXZ promotes glutathione metabolism and inhibits ferroptosis via p53/SLC7A11/GPX4 and Keap1/Nrf2/HO‐1 pathways. SXZ is a novel neuroprotective agent against age‐related cognitive decline.
Mengya Liu, Shunyi Li, Yonglin Liang, Yugui Zhang, Xutong Jia, Yongqiang Duan, Min Bai   +6 more
wiley   +1 more source

Magnetic Graphitic Carbon Nitride-Catalyzed Highly Efficient Construction of Functionalized 4H-Pyrans

, 2018
A high-yielding, practical, efficient, and environmentally benign one-pot multicomponent synthesis of functionalized 2-amino-4H-pyrans from β-dicarbonyl compounds, malononitrile, and aldehydes is presented.
Najmedin Azizi, Tahereh Ahooie, Mohammad Hashemi, Issa Yavari   +3 more
core   +1 more source

Asymmetric Synthesis of Tertiary α‐Aryl Stereocentres in Tetrahydro‐4H‐pyran‐4‐ones Using Pd‐Catalyzed Decarboxylative Asymmetric Protonation

European Journal of Organic Chemistry, Volume 29, Issue 36, 24 September 2026.
The Pd‐catalyzed decarboxylative asymmetric protonation (DAP) has been developed for sterically hindered tetrahydro‐4H‐pyran‐4‐one derived α‐aryl‐β‐keto esters. A substrate scope of nine examples of DAP showed that substrates containing a di‐ortho methoxy substitution pattern on the aryl ring gave rise to the highest enantioselectivities of up to 85 ...
Fionn McNeill, Joffrey Scriven, Fritz Bahns, Anugam V. Krishna, Julia Bruno‐Colmenarez, Patrick J. Guiry   +5 more
wiley   +1 more source

Cytotoxic Activity of Some Spirooxindole-4H-pyran Derivatives

Journal of Pharmaceutical Research International, 2019
Aims: Isatin is a honored scaffold and one of the most favorable class of heterocyclic systems that possesses many interesting biological activities and well-tolerated in humans. Here a series of fifteen spirooxindole-4H-pyran derivatives containing both isatin and pyran moieties (ICa-ICo) will be examine for their anti-cancer activity. Study ...
Soghra Khabnadideh, Masoomeh Divar, Zahra Faghih, Zeinab Faghih   +3 more
openaire   +2 more sources

Deciphering the Medicinal Chemistry Aspects of Akt Inhibitors for the Management of Cancer: Structure–Activity Relationship Frameworks, Landscapes, and Optimization Approaches

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
This review majorly describes the systematic development of Akt inhibitors involving numerous heterocyclic scaffolds along with their structure activity relationships to explore anticancer therapeutic strategies. ABSTRACT The Akt pathway is dysregulated in cancer, leading to proliferation, decreased apoptosis, and metastasis, and hence is a major ...
Mayur S. Dhangar, Mahesh B. Palkar
wiley   +1 more source

Strategian kehittäminen paikalliseen nuorisojärjestöön. Hankasalmen 4H-yhdistyksen strategian kehittäminen [PDF]

, 2020
Paikallisiin 4H-yhdistyksiin ei ole Suomen 4H-liiton järjestöpäällikön tiedon mukaan tehty viimeisten vuosien aikana kuin kaksi strategiaa. 4H-yhdistyksessä työskennellessäni näin kuitenkin kuinka konkreettisen strategian olemassaolo helpottaisi ...
Nyyssönen, Sampsa
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Endophytic Fungi Natural Factories of Novel Bioactive Compounds

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
This review provides a systematic analysis of 242 natural products isolated from 42 genera of endophytic fungi, highlighting their remarkable structural diversity and broad spectrum of biological activities . ABSTRACT Endophytic fungi represent a prolific and chemically diverse source of novel specialized metabolites with significant pharmacological ...
Dilmurod Murodullayev, Jakhongir Movlanov, Liu Wei, Wei Liu, Maksud Isokov, Santosh Kumar Bose, Fazliddin Kobilov, Zamira Djumayeva, Buston Islamov, Jamila Sherkulova, Zafar Matyakubov, Muniskhon Meylieva, Munisa Ergasheva, Diyor Abduraxmanov, Guozheng Huang, Hongchen Jiang, Kakhramon Davranov, Guohui Pan, Nigora Rustamova   +18 more
wiley   +1 more source

Kuopion 4H-yhdistys ry:n verkostoyhteistyön kehittäminen: Case Puijo [PDF]

, 2021
Tämä opinnäytetyö käsittelee aihetta yhdistyksen verkostoyhteistyön kehittäminen. Tässä opinnäytetyössä pohdin ja esitän Kuopion 4H-yhdistyksen verkostoyhteistyön kehittämistä, esimerkkitoiminnan kautta.
Korhonen, Heini
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