Results 71 to 80 of about 29,486 (260)

The Functional Logic of Cytosolic 5’-Nucleotidases. [PDF]

open access: yesCurrent Medicinal Chemistry, 2013
Adenosine- and uridine-cytidine kinases, purine-nucleoside phosphorylase, hypoxanthine-guanine phosphoribosyl transferase, and several related enzymes, are components of the salvage pathways which reduce the loss of intracellular purine and pyrimidine rings.
P L, Ipata, F, Balestri
openaire   +2 more sources

Intrahepatic Cholangiocarcinoma: Epidemiological Trends, Risk Factors, Diagnostic Challenges, and Advances in Personalized Therapy—A Comprehensive Review

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Intrahepatic cholangiocarcinoma (iCCA) ranks as the second most common primary liver cancer, compared to about 20% of cases. Its global incidence has climbed over the past four decades, yet early detection remains indefinable due to its asymptomatic nature. Five‐year survival rate of approximately is under 10%.
Yaqoob Muhammad   +10 more
wiley   +1 more source

INFLUENCE OF ANTHELMINTIC DRUGS ON ACTIVITIES OF 5'-NUCLEOTIDASE Bothriocephalus scorpii (Cestoda: Bothriocephalidae)

open access: yesРоссийский паразитологический журнал, 2016
Activities and properties of 5'-nucleotidase in the subcellular fractions of Bothriocephalus scorpii are studied with the use of adenosine monophosphate, inosine monophosphate and cytidine monophosphate as substrates. The high activity of 5'-nucleotidase
E. A. BURENINA
doaj  

Activity an enzyme 5`-nucleotidase in patients with chronic hepatitis C [PDF]

open access: yesТерапевтический архив, 2019
Aim of the study. To determine the activity of enzyme 5`-nucleotidase depending on the of disseminated intravascular coagulation syndrome phases and duration of infection period in patients with chronic hepatitis C. Materials and methods.
N V Galeeva, I Kh Valeeva
doaj   +1 more source

Exacerbated ATP transmission in the carotid body is linked to glomus cell expansion in spontaneously hypertensive rats

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Exacerbated ATP signalling in the carotid body (CB) of spontaneously hypertensive rats (SHRs) arises from expansion of the chemosensory glomus cell compartment and reduced extracellular ATP metabolism, leading to increased purinergic drive.
Igor S. A. Felippe   +11 more
wiley   +1 more source

Brain ischemia alters platelet ATP diphosphohydrolase and 5'-nucleotidase activities in naive and preconditioned rats

open access: yesBrazilian Journal of Medical and Biological Research, 2000
The effects of transient forebrain ischemia, reperfusion and ischemic preconditioning on rat blood platelet ATP diphosphohydrolase and 5'-nucleotidase activities were evaluated. Adult Wistar rats were submitted to 2 or 10 min of single ischemic episodes,
S.S. Frassetto   +8 more
doaj   +1 more source

Effect of tenofovir on nucleotidases and cytokines in HIV-1 target cells. [PDF]

open access: yesPLoS ONE, 2013
Tenofovir (TFV) has been widely used for pre-exposure prophylaxis of HIV-1 infection with mixed results. While the use of TFV in uninfected individuals for prevention of HIV-1 acquisition is actively being investigated, the possible consequences of TFV ...
Nabanita Biswas   +6 more
doaj   +1 more source

Deregulation of ocular nucleotide homeostasis in patients with diabetic retinopathy [PDF]

open access: yes, 2016
Clear signaling roles for ATP and adenosine have been established in all tissues, including the eye. The magnitude of signaling responses is governed by networks of enzymes; however, little is known about the regulatory mechanisms of purinergic signaling
Aalto, Kristiina   +5 more
core   +1 more source

Efficient Gene Expression System in Medaka Embryos Enables Functional Characterization of nt5c1a Paralogs Involved in Inosine Monophosphate Metabolism

open access: yesgenesis, Volume 64, Issue 3, June 2026.
ABSTRACT Optimizing transient expression systems in fish embryos is crucial for rapid gene function analysis. Here, we established an efficient system in medaka (Oryzias latipes) embryos by evaluating nucleic acid type and injection site. Our results revealed that injecting the elongation factor 1αA (ef1αA) promoter‐driven plasmid into the yolk yielded
Yu Murakami   +3 more
wiley   +1 more source

A review on laboratory liver function tests [PDF]

open access: yesThe Pan African Medical Journal, 2009
Laboratory liver tests are broadly defined as tests useful in the evaluation and treatment of patients with hepatic dysfunction. The liver carries out metabolism of carbohydrate, protein and fats. Some of the enzymes and the end products of the metabolic
Shruthi Kulkarni   +5 more
doaj  

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