Results 51 to 60 of about 14,806 (151)
Background Female sex hormones used in feminizing hormone therapy (FHT) may influence activation and persistence of HIV pre‐exposure prophylaxis (PrEP) medications. The clinical relevance of this interaction remains unclear, particularly for transgender and cisgender women (TGW and CGW).
Elizabeth Hastie +10 more
wiley +1 more source
Activities and properties of 5'-nucleotidase in the subcellular fractions of Bothriocephalus scorpii are studied with the use of adenosine monophosphate, inosine monophosphate and cytidine monophosphate as substrates. The high activity of 5'-nucleotidase
E. A. BURENINA
doaj
The effects of transient forebrain ischemia, reperfusion and ischemic preconditioning on rat blood platelet ATP diphosphohydrolase and 5'-nucleotidase activities were evaluated. Adult Wistar rats were submitted to 2 or 10 min of single ischemic episodes,
S.S. Frassetto +8 more
doaj +1 more source
The Functional Logic of Cytosolic 5’-Nucleotidases. [PDF]
Adenosine- and uridine-cytidine kinases, purine-nucleoside phosphorylase, hypoxanthine-guanine phosphoribosyl transferase, and several related enzymes, are components of the salvage pathways which reduce the loss of intracellular purine and pyrimidine rings.
P L, Ipata, F, Balestri
openaire +2 more sources
ABSTRACT Purpose To investigate the expression profile of IL‐6 in patients with acute promyelocytic leukemia (APL) and its role in modulating the ability of hPMSCs to regulate the differentiation of NB4 cells. Methods Peripheral blood samples were obtained from newly diagnosed APL patients and healthy controls.
Rong Qi +4 more
wiley +1 more source
Activity an enzyme 5`-nucleotidase in patients with chronic hepatitis C [PDF]
Aim of the study. To determine the activity of enzyme 5`-nucleotidase depending on the of disseminated intravascular coagulation syndrome phases and duration of infection period in patients with chronic hepatitis C. Materials and methods.
N V Galeeva, I Kh Valeeva
doaj +1 more source
Hypoxia, oncogenic signaling, transcriptional and epigenetic remodeling, and H. pylori–microbiota interactions drive the Warburg effect in gastric cancer. Enhanced glycolysis and lactate export support biosynthesis, remodel the tumor microenvironment, promote stromal activation and immune suppression, and reveal actionable biomarkers and therapeutic ...
Guanmo Liu +7 more
wiley +1 more source
Nucleotide Metabolism in Health and Disease
Nucleotide metabolism, including de novo synthesis, salvage pathways, and catabolism, when dysregulated contributes to cancer, immune disorders, metabolic and urological diseases, and radiation injury. Metabolites such as adenosine, cGAMP, NAD, and cAMP and enzymes like RNR are promising therapeutic targets and biomarkers.
Xiaoying Zhao +7 more
wiley +1 more source
A review on laboratory liver function tests [PDF]
Laboratory liver tests are broadly defined as tests useful in the evaluation and treatment of patients with hepatic dysfunction. The liver carries out metabolism of carbohydrate, protein and fats. Some of the enzymes and the end products of the metabolic
Shruthi Kulkarni +5 more
doaj
Abstract Bladder cancer is one of the leading causes of cancer‐related mortality worldwide. Long‐term survival is particularly poor in patients with muscle‐invasive bladder cancer (MIBC). Modulation of purinergic signaling through the ectonucleotidases CD39 and CD73 has emerged as a promising therapeutic strategy in cancer medicine.
Stephan Ledderose +5 more
wiley +1 more source

