Results 41 to 50 of about 14,806 (151)

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Mechanism of nitrogen metabolism-related parameters and enzyme activities in the pathophysiology of autism

Journal of Neurodevelopmental Disorders, 2012
Background There is evidence that impaired metabolism play an important role in the etiology of many neuropsychiatric disorders. Although this has not been investigated to date, several recent studies proposed that nitrogen metabolism-related parameters ...
Abu Shmais Ghada A, Al-Ayadhi Laila Y, Al-Dbass Abeer M, El-Ansary Afaf K   +3 more
doaj   +1 more source

COMPARATIVE STUDY ON THE ACTIVITY OF 5'-NUCLEOTIDASE 5-NT AND GAMMA GLUTAMYL TRANSFERASE (GGT) IN SOME TISSUES OF DONKEYS, CALVES AND GOATS (THE EFFECT OF FREEZING AND THAWING) (With One Table and 2 Figures) [PDF]

Assiut Veterinary Medical Journal, 2006
5'-nucleotidase (5'-NT) and Gamma glutamyl transferase (GGT) activity was measured in the tissues of four 2-6 years old donkeys; four 6-9 month old castrated male goats and four 6-9 month old male calves.
S.E.M. BARAKAT, I.M.T. FADLALLA, AMEL O. BAKHIET   +2 more
doaj   +1 more source

From biology to biotechnology: Host‐regulation factors from parasitoid wasps are a source of bioactive molecules with translational potential

Insect Molecular Biology, EarlyView.
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto, Andrew A. Walker, Glenn F. King   +2 more
wiley   +1 more source

Adenine nucleotide content and activity of AMP catabolism enzymes in the kidney of rats fed on diets with different protein and sucrose content

Біологічні студії
Background. Excessive consumption of sucrose or protein deficiency in the diet can induce metabolic disorders in the kidney, whose functioning requires significant ATP energy expenditure.
Halyna Kopylchuk, Oksana Voloshchuk
doaj   +1 more source

Impact of Zinc‐Dependent Enzymes on Zinc Deficiency and Inflammatory Response in Ulcerative Colitis

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aim Zinc (Zn) deficiency occurs in 40% of patients with ulcerative colitis (UC). Although Zn‐dependent enzymes are involved in intestinal immune regulation, their relationships with Zn deficiency and mucosal inflammation remain unclear.
Yuki Murakami, Taiho Kambe, Yu Kobayashi, Aki Sakatani, Katsuyoshi Ando, Nobuhiro Ueno, Kentaro Moriichi, Mikihiro Fujiya   +7 more
wiley   +1 more source

Efn1 and Efn2 are extracellular 5'-nucleotidases induced during the fission yeast response to phosphate starvation

mBio
The fission yeast PHO regulon genes pho1, pho84, and tgp1—encoding a cell surface-associated acid phosphatase (Pho1), a plasma membrane inorganic phosphate transporter (Pho84), and a plasma membrane glycerophosphocholine transporter (Tgp1)—are strongly ...
Aleksei Innokentev, Ana M. Sanchez, Mara Monetti, Beate Schwer, Stewart Shuman   +4 more
doaj   +1 more source

High‐altitude headache: Insights into pathophysiology and potential treatment implications

The Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude headache occurs during prolonged exposure to low oxygen, such as during ascent to high altitude. Several risk factors increase its likelihood, with the degree of hypoxia, often driven by rapid ascent to greater altitudes, being the most prominent factor.
Marika Falla, Florian Frank, Giacomo Strapazzon, Justin Lawley   +3 more
wiley   +1 more source

A nucleotide metabolite controls stress-responsive gene expression and plant development.

PLoS ONE, 2011
Abiotic stress, such as drought and high salinity, activates a network of signaling cascades that lead to the expression of many stress-responsive genes in plants. The Arabidopsis FIERY1 (FRY1) protein is a negative regulator of stress and abscisic acid (
Hao Chen, Baichen Zhang, Leslie M Hicks, Liming Xiong   +3 more
doaj   +1 more source

Autoimmunity in CD73/Ecto-5'-nucleotidase deficient mice induces renal injury. [PDF]

PLoS ONE, 2012
Extracellular adenosine formed by 5'-ectonucleotidase (CD73) is involved in tubulo-glomerular feedback in the kidney but is also known to be an important immune modulator.
Cornelia Blume, Agnieszka Felix, Nelli Shushakova, Faikah Gueler, Christine Susanne Falk, Hermann Haller, Juergen Schrader   +6 more
doaj   +1 more source