Results 21 to 30 of about 29,486 (260)
Comparative Study of 5’- Nucleotidase Test in Various Liver Diseases [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: The liver regulates many important metabolic functions. The 5’-nucleotidase activity is increased in obstructive jaundice, parenchymal liver disease, and hepatic metastases. Aim: This study was conducted to assess the serum levels of 5’-
Mohd Azam Hyder +2 more
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Tikrit Journal of Pure Science, 2023 One of the hydrolytic enzymes that catalyzes the hydrolysis of 5' -nucleotides into ribonucleosides and phosphate is the 5'nucleotidase, which is found in several organs.
Sameer M. Al-Gorany +1 more
doaj +1 more source
Nature, 1952 REIS1–4 has demonstrated the presence of a phosphatase in various tissues specifically hydrolysing 5-nucleotides, for example, adenosine-5-phosphate. One of us has previously reported5 that normal blood serum has a low 5-nucleotidase activity corresponding to about 1/10 of its non-specific alkaline phosphatase activity towards glycerophosphate. In bone
T F, DIXON, M, PURDON
openaire +3 more sources
Hepatology, EarlyView., 2022 Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong +9 more
wiley +1 more source
Effects of physical exercise on the functionality of human nucleotidases: A systematic review
Physiological Reports, 2022 Nucleotidases contribute to the regulation of inflammation, coagulation, and cardiovascular activity. Exercise promotes biological adaptations, but its effects on nucleotidase activities and expression are unclear.
Cesar Eduardo Jacintho Moritz +5 more
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Toxins, 2022 Snake venoms are complex cocktails of non-toxic and toxic molecules that work synergistically for the envenoming outcome. Alongside the immediate consequences, chronic manifestations and long-term sequelae can occur. Recently, extracellular vesicles (EVs)
Larissa Gonçalves-Machado +7 more
doaj +1 more source
Evidence for coordinated induction and repression of ecto-5'-nucleotidase (CD73) and the A2a adenosine receptor in a human B cell line [PDF]
, 2003 In the human B cell line P493-6 two mitogenic signals, the EpsteinBarr virus nuclear antigen 2 (EBNA2) and myc, can be independently regulated by means of an estrogen receptor fusion construct or an inducible expression vector, respectively.
Burgemeister R. +6 more
core +1 more source
Estradiol regulation of nucleotidases in female reproductive tract epithelial cells and fibroblasts. [PDF]
PLoS ONE, 2013 The use of topical and oral adenosine derivatives in HIV prevention that need to be maintained in tissues and cells at effective levels to prevent transmission prompted us to ask whether estradiol could influence the regulation of catabolic nucleotidase ...
Zheng Shen +7 more
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Activity-dependent release of Adenosine: a critical re-evaluation of mechanism [PDF]
, 2008 Adenosine is perhaps the most important and universal modulator in the brain. The current consensus is that it is primarily produced in the extracellular space from the breakdown of previously released ATP.
Wall, Mark J., Dale, Nicholas
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Expression of major ectonucleotidases after cortical stab brain injury in rats: A real-time PCR study [PDF]
Archives of Biological Sciences, 2014 Ectonucleotidases are cell surface-located enzymes responsible for the extracellular degradation of nucleotides. They are comprised of several protein families: ectonucleoside triphosphate diphosphohydrolases (E-NTPDase), ectonucleotide ...
Parabucki Ana +6 more
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