Results 111 to 120 of about 5,174,697 (237)

Heme deficiency in skeletal muscle exacerbates sarcopenia and impairs autophagy by reducing AMPK signaling

Scientific Reports
Heme serves as a prosthetic group in hemoproteins, including subunits of the mammalian mitochondrial electron transfer chain. The first enzyme in vertebrate heme biosynthesis, 5-aminolevulinic acid synthase 1 (ALAS1), is ubiquitously expressed and ...
Takeru Akabane, Hiromori Sagae, Koen van Wijk, Shinichi Saitoh, Tomohiro Kimura, Satoshi Okano, Ken Kodama, Kiwamu Takahashi, Motowo Nakajima, Tohru Tanaka, Michiaki Takagi, Osamu Nakajima   +11 more
doaj   +1 more source

Time‐series multi‐omics analysis of micronutrient stress in Sorghum bicolor reveals iron and zinc crosstalk and regulatory network conservation

Plant Biology, EarlyView.
Overlap between Fe and Zn responsive gene regulatory networks (GRNs) were found, indicative of micronutrient crosstalk, and conservation of root and leaf GRNs and genes suggests strong constraint on homeostasis networks in plants. Abstract Micronutrient stress impacts growth, biomass production, and grain yield in crops.
A. Mishra, A. Bhat, S. Kumari, R. Sharma, J. Braynen, D. Tadesse, S. El Alaoui, S. Seaver, N. Grosjean, D. Ware, M. Xie, T. Paape   +11 more
wiley   +1 more source

Mitigating drought stress and enhancing quinoa productivity using iron and zinc nanoparticles

Agrosystems, Geosciences &Environment, Volume 9, Issue 1, March 2026.
Abstract In recent years, the cultivation area and consumption of quinoa (Chenopodium quinoa Willd) have increased in the country due to its nutritional properties and ability to grow in adverse conditions. Based on climate change scenarios, long periods of drought are expected, which emphasizes the need for planting and developing new plants that are ...
Nasim Pakbaz, Heshmat Omidi, Mohammad Hosein Bijeh Keshavarzi   +2 more
wiley   +1 more source

Monitoring the accumulation and dissipation of the photosensitizer protoporphyrin IX during standard dermatological methyl-aminolevulinate photodynamic therapy utilizing non-invasive fluorescence imaging and quantification [PDF]

, 2016
Author's post-print is subject to a Creative Commons Attribution Non-Commercial No Derivatives LicenseBACKGROUND: Dermatological methyl-aminolevulinate photodynamic therapy (MAL-PDT) is utilized to successfully treat dermatological conditions. This study
Campbell, Sandra M., Curnow, Alison, Tyrrell, Jessica S.   +2 more
core   +1 more source

RNA‐Based Therapies for Inherited Metabolic Disorders

Journal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Inherited metabolic disorders (IMDs) are a diverse and complex group of genetic conditions resulting from deficiencies in enzymes, transporters, or cofactors. These deficiencies lead to metabolic dysfunction and severe clinical consequences. Despite significant progress in understanding their molecular basis, treatment options remain limited ...
Reddy Sreekanth Vootukuri, Sonam Gurung, Roopkatha Ghosh, Philippa B. Mills, Julien Baruteau, Haiyan Zhou   +5 more
wiley   +1 more source

Determination of delta aminolevulinic acid levels in urine; a sensitive indicator of lead exposure in construction workers [PDF]

Al Ameen Journal of Medical Sciences, 2020
Background: Occupational exposure is a major source for lead poisoning in adults. Lead toxicity disrupts the functions of the digestive system, nervous system, respiratory system, reproductive system, etc.
Neelam J. Patil, Pooja V. Bhatt, Sachin A. Patharkar, Alka V. Nerurkar, Pradeep N. Surve, Kapil Bhatia   +5 more
doaj  

Photodynamic therapy: A promising new modality for the treatment of cancer [PDF]

, 1996
The first reports on photodynamic therapy (PDT) date back to the 1970s. Since then, several thousands of patients, both with early stage and advanced stage solid tumours, have been treated with PDT and many claims have been made regarding its efficacy ...
Baas, P. (Paul), Leengoed, H.L.L.M. (H. L L M) van, Meulen, F.W. (Freerk) van der, Schuitmaker, J.J. (J.), Star, W.M. (W.), Zandwijk, N. (Nico) van   +5 more
core   +1 more source

Surface‐Coated Inorganic Nanomaterials for Drug Delivery: Chemical Design, Biomedical Applications, and Mechanistic Insights

Advanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
This review explores how surface‐coated inorganic nanomaterials are chemically engineered for advanced drug delivery. It highlights design principles, coating strategies, and biomedical applications, emphasizing how surface chemistry governs biocompatibility, targeting, and controlled release.
Hossein Daneshgar, Sepideh Ahmadi, Nikzad Abbariki, Navid Rabiee, Sidi A. Bencherif   +4 more
wiley   +1 more source

Non‐Operable Squamous Cell Carcinoma of the Infraorbital Region Treated With Electrochemotherapy: A Case Report

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Cutaneous squamous cell carcinoma (cSCC) is a malignant epithelial tumor of the skin, classified as a nonmelanoma skin cancer. It may develop from precancerous conditions such as chronic inflammatory dermatoses, actinic keratosis, or actinic cheilitis, but can also arise de novo.
Gianluca Nicolai, Francesco Campanella, Sergio Alexandre Gehrke, Antonio Scarano   +3 more
wiley   +1 more source

Recent Progressions in Applications of Bioactive Polysaccharides in Food and Health Sciences: A Comprehensive Review

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Polysaccharides play a pivotal role in the development of safe and healthy foods. They ameliorate fatigue, preserve the microflora of the gastrointestinal tract, and provide health for the gut in living organisms. These biopolymers are applied for the fabrication of breakthrough drug delivery systems and potential platforms in regenerative medicine ...
M V N L Chaitanya, Bahjat Alhasso, Wadhah Hasan Alkhazali, Ashok Kumar Bishoyi, Rami Oweis, S. Renuka Jyothi, Rishiv Kalia, Laxmidhar Maharana, Ashish Singh Chauhan, Hayder Naji Sameer, Ahmed Yaseen, Zainab H. Athab, Mohaned Adil, Asghar Narmani, Bagher Farhood   +14 more
wiley   +1 more source