Results 1 to 10 of about 34,813 (257)

Growth-coupled selection of 5-aminolevulinic acid synthetase mutants for 5-aminolevulinic acid biosynthesis in Corynebacterium glutamicum [PDF]

Frontiers in Microbiology
Introduction5-Aminolevulinic acid (5-ALA) is a nonprotein amino acid with broad applications in agriculture, medicine, and the food industry. In recent years, substantial efforts have been devoted to enhancing its biosynthesis.
Peng Yang, Peng Yang, Peng Yang, Yutian Fan, Yajuan Zhao, Yan Yu, Xinping Yan, Lu Han, Xinqiang Song, An-dong Gong, An-dong Gong, An-dong Gong   +11 more
doaj   +5 more sources

5-Aminolevulinic acid improves chicken sperm motility [PDF]

Animal Bioscience, 2021
Objective This study investigated the effects of 5-aminolevulinic acid (5-ALA) on the motility parameters, mitochondrial membrane depolarization, and ATP levels in chicken sperm. Methods The pooled semen from Barred Plymouth Rock males was used.
Shin Taniguchi, Zhendong Zhu, Mei Matsuzaki, Masaoki Tsudzuki, Teruo Maeda   +4 more
doaj   +4 more sources

Derivatives of 5-aminolevulinic Acid for photodynamic therapy.

Perspectives in Medicinal Chemistry, 2007
Photodynamic therapy (PDT) is a clinical treatment that combines the effects of visible light irradiation with subsequent biochemical events that arise from the presence of a photosensitising drug (possessing no dark toxicity) to cause destruction of selected cells. Today, the most common agent used in dermatological PDT is 5-aminolevulinic acid (ALA).
Ryan F. Donnelly, Paul A. McCarron, A. David Woolfson   +2 more
openalex   +3 more sources

Effect of 5-aminolevulinic Acid on Mitochondrial Activity

Frontiers in Bioscience-Scholar, 2023
Background: Mitochondrial dysfunction is considered an important mechanism in the pathogenesis of various diseases. Therefore, mitochondria are currently being considered as subjects for targeted therapies, particularly, phototherapy using 5 ...
Yuliya V. Markina, Alexander M. Markin, Tatiana V. Kirichenko, Taisiya V. Tolstik, Vadim R. Cherednichenko, Diana G. Kiseleva, Alexander N. Orekhov   +6 more
doaj   +3 more sources

A case in which bladder cancer invaded the ureteral orifice and was resected via photodynamic diagnosis‐assisted transurethral resection involving orally administered 5‐aminolevulinic acid [PDF]

IJU Case Reports, 2019
Introduction Transurethral resection of bladder tumor is widely used in combination with photodynamic diagnosis to treat non‐muscle invasive bladder cancer.
Keitaro Watanabe, Suguru Shirotake, Yuta Umezawa, Takayuki Takahashi, Takeshi Yamanaka, Noriaki LSanto, Takashi Okabe, Gou Kaneko, Katsuhiro Sano, Masanori Yasuda, Kent Kanao, Masafumi Oyama, Koshiro Nishimoto   +12 more
doaj   +2 more sources

Identification of risk factors for post-induction hypotension in patients receiving 5-aminolevulinic acid: a single-center retrospective study [PDF]

JA Clinical Reports, 2020
Background 5-Aminolevulinic acid (5-ALA) is useful as a photodynamic agent, but its use commonly leads to hypotension. Although avoiding a mean arterial pressure (MAP) < 60 mmHg is important, the incidence of MAP < 60 mmHg when using 5-ALA is unclear ...
Tomoaki Yatabe, Takashi Karashima, Motohiko Kume, Yu Kawanishi, Hideo Fukuhara, Tetsuya Ueba, Keiji Inoue, Yoshiyasu Okuhara, Masataka Yokoyama   +8 more
doaj   +2 more sources

Photodynamic inactivation of Klebsiella pneumoniae biofilms and planktonic cells by 5-aminolevulinic acid and 5-aminolevulinic acid methyl ester [PDF]

Lasers in Medical Science, 2016
The treatment of Klebsiella pneumoniae, particularly extended-spectrum β-lactamase (ESBL)-producing K. pneumoniae, is currently a great challenge. Photodynamic antimicrobial chemotherapy is a promising approach for killing antibiotic-resistant bacteria ...
Han, L, Ishaq, HM, Lei, J, Liu, C, Nair, SP, Wang, L, Xu, J, Zhou, Y   +7 more
core   +5 more sources

Supplementation of 5-Aminolevulinic Acid Suppressed Body Weight Loss and Reduced Disease Severity During Eimeria tenella Infection in Broiler Chickens [PDF]

The Journal of Poultry Science
This study aimed to evaluate the effects of 5-aminolevulinic acid (5-ALA) supplementation in broiler chickens infected with Eimeria tenella. To assess these effects, chickens supplemented with 20 ppm 5-ALA (5-ALA group) were compared ...
Taqi Ahmad Hanif, Makoto Matsubayashi, Toshimitsu Hatabu   +2 more
doaj   +2 more sources

Case Report: Lack of Response to Givosiran in a Case of ALAD Porphyria

Frontiers in Genetics, 2022
Introduction: 5-Aminolevulinic acid dehydratase (ALAD) porphyria (ADP) is an autosomal recessive disease characterized by a profound deficiency in ALAD, the second enzyme in the heme biosynthetic pathway, and acute neurovisceral attacks with abdominal ...
Erica Graff, Karl E. Anderson, Cynthia Levy, Cynthia Levy   +3 more
doaj   +1 more source

Photodynamic therapy of acne

Biomedical Photonics, 2023
Acne is one of the most common skin conditions in the world. A number of studies have shown that photodynamic therapy (PDT) is safe and effective for both inflammatory and non-inflammatory acne and can significantly improve skin conditions in this ...
E. V. Filonenko, V. I. Ivanova-Radkevich
doaj   +1 more source