Zn protoporphyrin IX is formed not from heme but from protoporphyrin IX [PDF]
We examined the effects of exogenous myoglobin, a bivalent chelator, and nitrite on Zn protoporphyrin IX (ZPP) formation by using model systems. ZPP was formed in a model solution without addition of exogenous myoglobin. After incubation, the amount of ZPP in a model solution was increased but that of heme was not decreased compared with the amounts ...
Takanori Nsihimura, Jun-Ichi Wakamatsu
exaly +5 more sources
Effects of Mono- and Dicapsaicinoid Functionalization on the Physicochemical Properties and Antimicrobial Photodynamic Activity of Protoporphyrin IX. [PDF]
Capsaicin functionalization of Protoporphyrin IX influences aggregation behavior, lipophilicity, and photodynamic activity. A monosubstituted derivative exhibits enhanced antimicrobial photoinactivation of Staphylococcus aureus, whereas increased functionalization does not improve efficacy.
Cunha IVD +10 more
europepmc +2 more sources
Piperazine and Morpholine Protoporphyrin IX Derivatives Intensify Biomolecules Oxidation and Phototoxicity in Triple-Negative Breast Cancer. [PDF]
Protoporphyrin IX derivatives bearing piperazine or morpholine substituents exhibit enhanced cellular retention and photodynamic activity in triple‐negative breast cancer cells. Structural modification promotes oxidative stress, alters mitochondrial membrane potential, and increases caspase‐3 activity, providing new structure–activity relationship ...
Franco MDS +11 more
europepmc +2 more sources
Simultaneous determination of protoporphyrin IX and magnesium protoporphyrin IX in Arabidopsis thaliana and Camellia sinensis using UPLC-MS/MS [PDF]
Backgrounds Insertion of Mg2+ into protoporphyrin IX (PPIX) to produce magnesium-protoporphyrin IX (Mg-PPIX) was the first step toward chlorophyll biosynthesis, which not only imparts plants green pigmentation but underpins photosynthesis.
Chenyu Zhang +3 more
doaj +2 more sources
The nitrosyl–heme complex is considered the pigment responsible for the development of reddish colour in cooked hams. However, the same reddish colour was observed in a nitrite-free product elaborated with polyphenols, suggesting the presence of other ...
Claudia Giménez-Campillo +6 more
doaj +3 more sources
Synthetic biology-instructed transdermal microneedle patch for traceable photodynamic therapy
5-Aminolevulinic acid-based photodynamic therapy heavily depends on the biological transformation efficiency of 5-aminolevulinic acid to protoporphyrin IX, while the lack of an effective delivery system and imaging navigation are major hurdles in ...
Gang He +7 more
doaj +1 more source
Gold Nanoparticles/Nanographene-Based 3D Sensors Integrated in Mini-Platforms for Thiamine Detection
Vitamins are essential for sustaining daily activities and perform crucial roles in metabolism, such as preventing vascular events and delaying the development of diabetic nephropathy.
Damaris-Cristina Gheorghe +3 more
doaj +1 more source
Eggshell colour is the unique appearance and economically valuable trait of eggs, whereas the colour is often short of uniformity, especially in the blue-shelled breeds, hence, their pigment differences and molecular mechanism need clarity.
Huanhuan Wang +6 more
doaj +1 more source
A photosensitizing fusion protein with targeting capabilities
The photodynamic treatment for antimicrobial applications or anticancer therapy relies on reactive oxygen species generated by photosensitizing molecules after absorption of visible or near-infrared light.
Bruno Stefano +8 more
doaj +1 more source
Mechanisms associated with the depigmentation of brown eggshells: a review
: Eggshell color is an important shell quality trait that influences consumer preference. It is also of particular importance with respect to sexual signaling and the physiological and mechanical properties of shell pigment.
Ming-Yuan Lu +6 more
doaj +1 more source

