Results 21 to 30 of about 13,793 (186)
Total Synthesis of Hematoporphyrin and Protoporphyrin; a Conceptually New Approach
CHIMIA, 2013 The total synthesis of protoporphyrin IX and its disodium salt using a new alternative method to the classical MacDonald condensation is reported.
Pierre Martin +4 more
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Frontiers in Medicine, 2021 Introduction: Subjects with erythropoietic protoporphyria rely on broad-spectrum sunscreens with high sun protection factor, which is not informative on efficacy in the absorption spectrum of protoporphyrin IX, spanning visible radiation and peaking ...
Alvise Sernicola +7 more
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BMC Oral Health, 2020 Background The primary aim of this study was to observe the effect of 5-ALA-mediated photodynamic therapy on oral squamous cell carcinoma in vitro. Methods SCC25 cells were divided into the observation group and the blank control group.
Ying Ma +4 more
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Molecular Dynamics of Cobalt Protoporphyrin Antagonism of the Cancer Suppressor REV-ERBβ
Molecules, 2021 Nuclear receptor REV-ERBβ is an overexpressed oncoprotein that has been used as a target for cancer treatment. The metal-complex nature of its ligand, iron protoporphyrin IX (Heme), enables the REV-ERBβ to be used for multiple therapeutic modalities as a
Taufik Muhammad Fakih +4 more
doaj +1 more source
Fluorescence‐based discrimination of breast cancer cells by direct exposure to 5‐aminolevulinic acid
Cancer Medicine, 2019 Protoporphyrin IX‐fluorescence measurement is a powerful in situ approach for cancer detection after oral/topical administration of 5‐aminolevulinic acid.
Midori Morita +8 more
doaj +1 more source
Synthesis of Two Compounds with Self-Assembled Monolayer Properties: Riboflavin 2', 3', 4' , 5' Tetra Octadecanoate & Bis (Phosphatidyl Ethanol) Protoporphyrin IX Amide [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2011 Riboflavin and protoporphyrin IX are two molecules that participate in oxidation and reduction reactions in the living cell. Changing some functional groups of riboflavin and protoporphyrin IX can provide compounds with self-assembled monolayer ...
Mohammad Mirzaei Salehabady +4 more
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Antimicrobial Photodynamic Therapy in the Control of COVID-19
Antibiotics, 2020 Antimicrobial photodynamic therapy (aPDT), using well known, safe and cost-effective photosensitizers, such as phenothiazines, e.g., methylene blue (MB), or porphyrins, e.g., protoporphyrin-IX (PP-IX), might help to mitigate the COVID-19 either to ...
Adelaide Almeida +2 more
doaj +1 more source
Protoporphyrin IX: the Good, the Bad, and the Ugly [PDF]
The Journal of Pharmacology and Experimental Therapeutics, 2016 Protoporphyrin IX (PPIX) is ubiquitously present in all living cells in small amounts as a precursor of heme. PPIX has some biologic functions of its own, and PPIX-based strategies have been used for cancer diagnosis and treatment (the good). PPIX serves as the substrate for ferrochelatase, the final enzyme in heme biosynthesis, and its homeostasis is ...
Madhav, Sachar +2 more
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Inactivation of Dengue and Yellow Fever viruses by heme, cobalt-protoporphyrin IX and tin-protoporphyrin IX [PDF]
Journal of Applied Microbiology, 2016 To investigate the effect of heme, cobalt-protoporphyrin IX and tin-protoporphyrin IX (CoPPIX and SnPPIX), macrocyclic structures composed by a tetrapyrrole ring with a central metallic ion, on Dengue Virus (DENV) and Yellow Fever Virus (YFV) infection.Treatment of HepG2 cells with heme, CoPPIX and SnPPIX after DENV infection reduced infectious ...
I, Assunção-Miranda +8 more
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Association of iron‐protoporphyrin‐IX (hemin) with myosins [PDF]
FEBS Letters, 1990 Addition of myosins isolated from guinea pig heart and rabbit skeletal muscle to hemin solutions resulted in the appearance of new absorption spectra indicating association of hemin and the myosins. Binding stoichiometry based on absorption changes was found to be two hemin sites per myosin molecule.
Bhoite-Solomon, V. +2 more
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