Results 21 to 30 of about 13,836,709 (221)

Synthetic biology-instructed transdermal microneedle patch for traceable photodynamic therapy

Nature Communications, 2022
5-Aminolevulinic acid-based photodynamic therapy heavily depends on the biological transformation efficiency of 5-aminolevulinic acid to protoporphyrin IX, while the lack of an effective delivery system and imaging navigation are major hurdles in ...
Gang He, Yashi Li, Muhammad Rizwan Younis, Lian-Hua Fu, Ting He, Shan Lei, Jing Lin, Peng Huang   +7 more
doaj   +1 more source

5-Aminolevulinic Acid and Red Led in Endodontics: A Narrative Review and Case Report

Gels, 2022
The present study aims to discuss the main factors involving the use of 5-aminolevulinic acid together with red LED light and its application in endodontic treatment through a narrative review and a case report. Persistence of microorganisms remaining on
Simonetta D’Ercole, Teocrito Carlesi, Tatiane Cristina Dotta, Tania Vanessa Pierfelice, Emira D’Amico, Domenico Tripodi, Giovanna Iezzi, Adriano Piattelli, Morena Petrini   +8 more
doaj   +1 more source

5‐Aminolevulinic Acid Dehydratase [PDF]

European Journal of Biochemistry, 1981
The thiophilic reagent 5,5′‐dithiobis(2‐nitrobenzoic acid) (Nbs2) reacts with four sulphydryl groups in native 5‐aminolevulinic acid dehydratase from bovine liver (groups I, II, III and IV). All four of these groups exhibit various degrees of half‐site reactivity.
J S, Seehra, M G, Gore, A G, Chaudhry, P M, Jordan   +3 more
openaire   +2 more sources

Photodynamic therapy in the treatment of extramammary paget’s disease

Biomedical Photonics, 2022
Extramammary Paget’s disease (EMPD) is a rare tumor that predominantly affects the skin containing apocrine glands. Due to insufficient data on the effectiveness of different methods, there is no single therapeutic approach to the treatment of patients ...
E. V. Filonenko, V. Ivanova-Radkevich
doaj   +1 more source

Transurethral resection and surveillance of bladder cancer supported by 5-aminolevulinic acid-induced fluorescence endoscopy [PDF]

, 1999
Purpose: We determined whether neoplastic disease, which was missed under white light can be found during transurethral resection of bladder cancer by 5-aminolevulinic acid-induced porphyrin fluorescence.
Kriegmair, Martin, Knüchel, Ruth, Stepp, Helmut, Zaak, Dirk, Stepp, Herbert, Hofstetter, Alfons, Baumgartner, Reinhold, Dirk Zaak, Helmut Stepp, Reinhold Baumgartner, Martin Kriegmair, Alfons Hofstetter, Herbert Stepp, Ruth Knuechel   +13 more
core   +1 more source

Kinetics of 5-aminolevulinic acid-induced fluorescence in organ cultures of bronchial epithelium and tumor [PDF]

, 2002
Background: 5-Aminolevulinic acid (5-ALA)-induced protoporphyrin IX (PPIX) fluorescence improves the differentiation of tumor and normal tissue in the bladder, skin and brain. Objective: The kinetics of 5-ALA-induced protoporphyrin IX (PPIX) fluorescence
Bergner, Albrecht, Maier, Irmgard, Gamarra, Fernando, Al-Batran, Salah, Baumgartner, Reinhold, Wagner, Simon, Castro, Mirna, Hautmann, Hubert, Huber, Rudolf M.   +8 more
core   +1 more source

Effects on Gram-Negative and Gram-Positive Bacteria Mediated by 5-Aminolevulinic Acid and 5-Aminolevulinic Acid Derivatives [PDF]

Antimicrobial Agents and Chemotherapy, 2008
ABSTRACT Due mainly to the extensive use of antibiotics, the spread of multiresistant bacterial strains is one of the most worrying threats to public health. One strategy that can be used to overcome potential shortcomings might be the inactivation of these microorganisms by 5-aminolevulinic acid (5-ALA) or 5-ALA derivative ...
Fotinos, Nicolas, Convert, Maruska, Piffaretti, Jean-Claude, Gurny, Robert, Lange, Norbert   +4 more
openaire   +4 more sources

Photodynamic therapy of prostate cancer by means of 5-aminolevulinic acid-induced protoporphyrin IX - In vivo experiments on the dunning rat tumor model [PDF]

, 2004
Objective: In order to expand the use of photodynamic therapy (PDT) in the treatment of prostate carcinoma (PCA), the aim of this study was to evaluate PDT by means of 5-aminolevulinic acid (5-ALA)-induced protoporphyrin IX ( PPIX) in an in vivo tumor ...
Schneede, Peter, Lein, Michael, Bise, Karl, Zaak, Dirk, Baumgartner, Reinhold, Stocker, Susanne, Höppner, Michael, Kriegmair, Martin, Knüchel, Ruth, Hofstetter, Alfons, Frimberger, Dominic, Sroka, Ronald, Reich, Oliver   +12 more
core   +1 more source

Identification of risk factors for post-induction hypotension in patients receiving 5-aminolevulinic acid: a single-center retrospective study

JA Clinical Reports, 2020
Background 5-Aminolevulinic acid (5-ALA) is useful as a photodynamic agent, but its use commonly leads to hypotension. Although avoiding a mean arterial pressure (MAP) < 60 mmHg is important, the incidence of MAP < 60 mmHg when using 5-ALA is unclear ...
Tomoaki Yatabe, Takashi Karashima, Motohiko Kume, Yu Kawanishi, Hideo Fukuhara, Tetsuya Ueba, Keiji Inoue, Yoshiyasu Okuhara, Masataka Yokoyama   +8 more
doaj   +1 more source

A New Synthesis of 5-Aminolevulinic Acid.

Agricultural and Biological Chemistry, 1991
(1991). A New Synthesis of 5-Aminolevulinic Acid. Agricultural and Biological Chemistry: Vol. 55, No. 6, pp. 1687-1688.
KAWAKAMI, Hiroshi, EBATA, Takashi, MATSUSHITA, Hajime   +2 more
openaire   +2 more sources